Am J Transplant, Volume 18, Suppl 3 Archives - Page 16 of 211 - ATC Abstracts

2018 American Transplant Congress
Living Donor Liver Transplant (LDLT) at a Single Center- Intraoperative Technical Modifications and Optimization of Flow Dynamics to Improve Outcomes
A. Humar, S. Ganesh, A. Tevar, M. Molinari, C. Hughes.
Surgery, University of Pittsburgh, Pittsburgh.
Objectives: While LDLT represents the dominant method of LTx in the East, it remains an underutilized procedure in the US, accounting for <5% of all…
2018 American Transplant Congress
Complications and QoL after Living Donor Hepatectomy: Analysis of 176 Cases at a Single Center
S. Chinnakotla, V. Kirchner, S. Mongin, D. Berglund, O. Serrano, T. Pruett.
Department of Surgery, University of Minnesota, Minneapolis.
Background: Living liver donation is one of the most selfless and humane acts a person can perform. Few single-center reports have been published specifically evaluating…
2018 American Transplant Congress
Postoperative Renal Function Predicts Length of Stay for Incisional Hernia Repair after Liver Transplantation
J. Butler, D. O'Brien, J. Kays, C. Kubal, B. Ekser, J. Fridell, R. Mangus, J. Powelson.
Transplant Surgery, Indiana University, Indianapolis, IN.
Background: Incisional hernia repair (IHR) is the most frequently performed general surgery procedure after orthotopic liver transplantation (OLT). Although enhanced recovery protocols for general surgery…
2018 American Transplant Congress
Living Donor Liver Transplantation for Hepatocellular Carcinoma beyond UCSF Criteria: Can We Achieve a Modest Long-Term Survival? A Single Center Retrospective Analysis of Using Extended Criteria
A. Thorat, L.-B. Jeng, S.-C. Hsu, C.-C. Yeh, T.-H. Chen, H.-R. Yang, K.-S. Poon, P.-C. Li.
Organ Transplantation Center, China Medical University Hospital, Taichung, Taiwan.
Milan's criteria were universally validated for LT in HCC patients and, were accepted as allocation criteria of UNOS in 2001 & Eurotransplantation in 2006. However,…
2018 American Transplant Congress
Delivery of Culturally-Competent Transplant Care among Hmong Kidney Transplant Recipients: Outcomes from a Single Institution
M. Odegard,¹ O. Serrano,¹ K. Peterson,¹ S. Mongin,² D. Berglund,³ D. Vock,⁴ S. Chinnakotla,¹ T. Dunn,¹ E. Finger,¹ R. Kandaswamy,¹ T. Pruett,¹ A. Matas.¹
¹Division of Transplantation, Division of Surgery, University of Minnesota, Minneapolis, MN; ²Biostatistical Design and Analysis Center, Clinical and Translational Science Institute, University of Minnesota, Minneapolis, MN; ³Informatics Services for Research and Reporting, Fairview, University of Minnesota, Minneapolis, MN; ⁴Division of Biostatistics, School of Public Health, University of Minnesota, Minneapolis, MN.
OBJECTIVE: Kidney transplantation (KT) entails delivery of complex, well-coordinated, multidisciplinary care. Cultural and linguistic discordance among transplant providers and patients can lead to healthcare disparities.…
2018 American Transplant Congress
How Early is Too Early for a Preemptive Kidney Transplant? A Markov Decision Process-Based Retrospective Analysis
M. Kurt,¹ A. Khojandi,² M. Barah,² B. Tanriover.³
¹Economic and Data Sciences, Merck Research Labs, North Wales, PA; ²Industrial and Systems Engineering, University of Tennessee, Knoxville, TN; ³Division of Nephrology, UT Southwestern Medical Center, Dallas, TX.
Purpose: Living-donor preemptive kidney transplantation (PKT) provides survival and financial benefits. However there is no guidelines to assist with PKT timing.Method: We considered the transplant…
2018 American Transplant Congress
Designing Novel Selective Immunoproteasome Inhibitors Reveals a Critical Role of the Immunoproteasome in Protecting Antibody Secreting B Cells from Apoptosis
J. Assaker,¹ N. Murakami,¹ S. Eskandari,¹ M. Uehara,¹ C. Nathan,² H. Li,³ G. Lin,² J. Azzi.¹
¹Transplantation Renal Center, Harvard Medical School, Boston; ²Microbiology and Immunology, Weill Cornell Medicine, New York; ³Cryo-EM Structural Biology Laboratory, Van Andel Research Institute, Grand Rapids.
Constitutive proteasomes (c-20S) are ubiquitously-expressed cellular proteases that degrade polyubiquitinated proteins and regulate cell functions. Its inhibitor, bortezomib, is a plasma cell-targeted therapy used in…
2018 American Transplant Congress
Improvement of Metabolic Function after Intra-Portal Allogeneic Islet Transplantation by Induction Treatment of the Non-Hematopoetic Erytropoetin Analogue Cibinetide in a Mouse Model
M. Yao,¹ M. Watanabe,^1,2 S. Sun,¹ B. Ericzon,¹ T. Lundgren,¹ M. Kumagai-Braesch.¹
¹Department of Transplantation Surgery, Karolinska University Hospital, Stockholm, Sweden; ²Department of Gastroenterological Surgery I, Hokkaido University Graduate School of Medicine, Sapporo, Japan.
IntroductionRecently, we have demonstrated that cibinetide, a non-hematopoetic erytropoetin analogue, protected pancreatic islets from cytokine-induced damage and apoptosis and ameliorated the early inflammatory response following…
2018 American Transplant Congress
The TRANSFORM Study: Infection Outcomes with Everolimus Plus Reduced Calcineurin Inhibitor and Mycophenolate Plus Standard Calcineurin Inhibitor Regimens in De Novo Kidney Transplant Recipients
F. Vincenti, J. Cruzado, S. Mulgaonkar, V. Garcia, D. Kuypers, M. Buchler, F. Citterio, U. Huynh-Do, W-.L. Luo, P. Bernhardt, C. Sommerer.
TRANSFORM Study Group, Novartis Pharma AG, Basel, Switzerland.
Purpose: Post-transplant (Tx) bacterial and viral infections are known to affect graft and patient survival. Accumulating evidence supports the protective effect of everolimus (EVR) against…
2018 American Transplant Congress
Renal Function, Blood Pressure, and Histologic Changes in Living Kidney Transplant Recipients from Hypertensive Donors
T. Dienemann, J. Schellenberg, K. Amann, K. Heller, A. Weidemann.
Nephrology and Hypertension University Hospital Erlangen, University of Erlangen-Nuremberg, Erlangen, Germany.
Little is known if a kidney from a hypertensive donor performs equally compared to a kidney from a non-hypertensive donor. The present study examines the…