Am J Transplant, Volume 18, Suppl 3 Archives - Page 16 of 211 - ATC Abstracts

2018 American Transplant Congress
Organ Transplantation Associated with High Incidence of Anal Cancer and Pre-Cancer Lesions among HIV-Infected Women and Men
P. Chin-Hong,¹ B. Barin,² M. Berry,¹ M. DaCosta,¹ T. Darragh,¹ L. Rosenthal,³ S. Bartlett,⁴ D. Dieterich,⁵ F. Poordad,⁶ N. Nissen,⁶ M. Wong,⁷ P. Stock,¹ J. Palefsky.¹
¹University of California, San Francisco, San Francisco; ²EMMES, Rockville; ³Columbia University, New York; ⁴University of Maryland, Baltimore; ⁵Icahn School of Medicine at Mount Sinai, New York; ⁶Cedars-Sinai Medical Center, Los Angeles; ⁷Beth Israel Deaconess Medical Center, Boston.
Objective: HIV-infected women and men and transplant recipients are two populations at increased risk of HPV-associated anal cancer but there is little published data. We…
2018 American Transplant Congress
Unsupervised Analysis of the Alloimmune Response in a Novel Model of Vascularized Composite Allotransplantation
J. Harden, A. Sang, X. Qu, C. Esquivel, O. Martinez, S. Krams.
Department of Surgery/Division of Abdominal Transplantation, Stanford University, Stanford, CA.
Vascularized composite allografts consists of skin, muscle, bone, and other tissues, and is more immunogenic than solid-organ allografts. Our laboratory developed a murine model to…
2018 American Transplant Congress
Dual Inhibition of PI3K and mTORC2 Causes ERK Hyperactivation Induced by HLA-II Antibody in Human Endothelium
Y-.P. Jin, E. Reed.
Pathology and Laboratory Medicine, David Geffen School of Medicine, UCLA, Los Angeles, CA.
Background: Endothelial cells (EC) line the inner surface of blood vessels and serve as the interface between recipient circulating blood and the donor allograft. Transplant…
2018 American Transplant Congress
A Follow-Up Report on the Use of IVIG+Rituximab to Reduce Donor Specific Antibodies and Improve Transplant Rates in Highly-Sensitized Patients Awaiting Deceased Donor Kidney Transplantation
R. Najjar, E. Huang, A. Vo, J. Choi, K. Lim, S. Louie, A. Peng, S. Sethi, M. Toyoda, X. Zhang, S. Jordan.
Medicine/Nephrology, Cedars Sinai Medical Center, Los Angeles, CA.
Introduction: Desensitization (DES) with IVIG/rituximab is associated with a reduction in donor specific antibodies (DSA), improved transplant rates and outcomes in highly-sensitized (HS) patients. We…
2018 American Transplant Congress
Kidney Transplantation and Progression of Peripheral Arterial Disease in the Ipsilateral Lower Extremity
A. Rasmussen,¹ R. Moore,¹ T. Schuler,¹ G. Todd,¹ K. Wen.²
¹Division of Urology, Department of Surgery, University of Alberta, Edmonton, AB, Canada; ²Division of Nephrology and Transplant Immunology, Department of Medicine, University of Alberta, Edmonton, AB, Canada.
Objectives:We aimed to investigate whether receiving a kidney transplant allograft graft increases the risk of ipsilateral lower limb amputation in patients with pre-existing peripheral arterial…
2018 American Transplant Congress
Estimation of Mortality on the Wait List
S. Asrani, L. Jennings, J. Trotter, G. Klintmalm.
Baylor University Medical Center, Dallas, TX.
Background: Since the introduction of MELD and MELDNa, the waitlist population has changed. Further, serum creatinine is a poor surrogate of renal dysfunction in patients…
2018 American Transplant Congress
Consequences of Being Listed at a Small Pancreas Program
S. Niederhaus,¹ M. Curry,² A. Fox,² J. Fridell,³ J. Odorico.⁴
¹Surgery, University of Maryland, Baltimore, MD; ²UNOS, Richmond, VA; ³Surgery, Indiana University, Indianapolis, IN; ⁴Surgery, University of Wisconsin, Madison, WI.
How pancreas transplant center (PTC) volume affects patient outcomes after listing is unclear. Low volumes may lengthen waiting times or limit access to transplantation. We…
2018 American Transplant Congress
Living Liver Donor Follow-Up: Fewer Than Half of Centers Meet Follow-Up Requirements in the US
A. Thomas, C. Holscher, A. Shaffer, J. Garonzik-Wang, A. Massie, D. Segev, M. Henderson.
JHU, Baltimore.
OPTN/UNOS began requiring 1-year living donor follow-up (LDF) for living liver donors (LLDs) in 2014. Compliance with a similar policy for living kidney donors was…
2018 American Transplant Congress
T Cell Exhaustion in Kidney Transplant Patients
M. Fribourg,¹ C. Fischman,² L. Anderson,² B. Burrell,³ P. Heeger,² P. Cravedi.²
¹Department of Neurology, Icahn School of Medicine, New York; ²Department of Medicine, Icahn School of Medicine, New York; ³Immune Tolerance Network, Bethesda.
Background: T cell exhaustion is a dysfunctional state that arises during chronic infection and cancer in response to persistence of high antigenic load. Whether chronic…
2018 American Transplant Congress
Donor Liver Apoptosis is Associated with Early Allograft Dysfunction and Short-Time Graft Survival after Liver Transplantation
Z. Guo, Z. Zhu, Y. Tang, S. Huang, Z. Zhang, X. He, G. Chen.
Organ Transplant Center, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China.
Aims The aim of the study was to determine whether donor liver apoptosis is predictive for early allograft dysfunction (EAD) and graft survival after liver…