2018 American Transplant Congress
C5aR Regulates Myeloid Derived Suppressor Cells (MDSCs) in Transplantation
Medicine, Icahn School of Medicine at Mount Sinai, New York, NY.
Prolonged survival of anti-CD154-(MR1)-treated murine heart transplant recipients is dependent on regulatory T cells (Treg) and MDSC. Based on studies in the tumor literature suggesting…2018 American Transplant Congress
Molecular Analysis of Acute Cellular Rejection in Clinical Face Transplants
Brigham and Women's Hospital, Boston.
Although monitoring and immunosuppression of vascularized composite allografts (VCA) draw experience from solid organ transplantation, VCAs pose unique challenges. A deeper understanding of mechanisms underlying…2018 American Transplant Congress
p16INK4a Deletion in Vascular Endothelium Improves Kidney Regeneration Post Ischemia Reperfusion Injury
Background: Ischemia Reperfusion injury (IRI) mediated cellular senescence in kidney allografts has been linked to a loss in regenerative potential and delayed graft function. Injured…2018 American Transplant Congress
Improving Prediction of Post-Transplant Death and Graft Loss with Expanded Clinical Data Collection
US transplant centers are graded for patient and graft survival of their recipients based on comparison to risk-adjusted expectations using elements captured in the national…2018 American Transplant Congress
Post‐Donation eGFR Levels Predicts New‐Onset Antihypertensive Medication Use after Living Kidney Donation
Limited data are available on the outcome implications of renal function after living kidney donation.We constructed a novel database linking SRTR registry identifiers, serum creatinine…2018 American Transplant Congress
The Predictive Power of MELD is Decreasing in the Era of Older, Sicker Patients
PurposeThe field of liver transplantation has shifted considerably in the MELD era. Liver allocation, immunosuppression, and etiologies of liver failure have changed over time, and…2018 American Transplant Congress
Economic Evaluation of Contemporary Kidney Transplant Practice
Kidney transplantation (KTx) has been established as the optimal therapy for medically suitable patients with end-stage renal disease, prolonging survival and reducing health care spending.…2018 American Transplant Congress
Information Needs of Adolescent Transplant Recipients Transitioning to Adult Care
Background: As adolescent and young adult (AYA) tx recipients transition to adulthood, a parallel transition in care is essential. The AYA should achieve skills for…2018 American Transplant Congress
Activity Nanosensors for Early and Noninvasive Detection of Acute Organ Transplant Rejection
Purpose: We engineered activity nanosensors that sense anti-allograft T cell activity in vivo to noninvasively detect the onset of acute cellular rejection from urine.Methods: Granzyme…2018 American Transplant Congress
IL-21 Regulates Creation of Tertiary Lymphoid Organs in Chronic Allograft Rejection
Background: IL-21 is a cytokine expressed almost exclusively by cells of the adaptive immune system, making it an attractive target for reducing chronic allograft rejection…
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