Am J Transplant, Volume 18, Suppl 3 Archives - Page 157 of 211 - ATC Abstracts

2018 American Transplant Congress
Mitochondrial Quality Control through PGC-1α in Syngenic Mouse Heart Transplant
A. Cherry,¹ K. Porter,¹ H. Suliman,¹ J. Wang,² M. Mulvihill,² A. Kirk.²
¹Anesthesiology, Duke University, Durham, NC; ²Surgery, Duke University, Durham, NC.
Intro: Impaired mitochondrial function plays a role in graft dysfunction after transplant, and recovery is facilitated by mitochondrial quality control (MQC). Two key elements of…
2018 American Transplant Congress
Noninvasive Quantization of Intra-Renal Allograft C4d Deposition with Targeted Ultrasound Imaging
T. Liao,¹ Y. Zhang,¹ J. Ren,² H. Zheng,¹ H. Zhang,² X. Liu,¹ T. Yin,² Q. Sun.¹
¹Organ Transplantation Research Institute, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China; ²Department of Medical Ultrasound, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China.
Antibody-mediated rejection (AMR) has emerged as the major cause of renal allograft dysfunction. C4d, a specific marker of AMR diagnosis, was strongly recommended for routine…
2018 American Transplant Congress
Building a Third-Party VST Bank from Scratch- The Cincinnati Experience
A. S. Nelson,¹ D. Heyenbruch,² X. Zhu,³ S. M. Davies,¹ C. Lutzko,³ C. Bollard,⁴ P. Hanley,⁴ T. Leemhuis,² L. Danziger-Isakov,⁵ M. S. Grimley.¹
¹Bone Marrow Transplant & Immune Deficiency, Cincinnati Children's Hospital Medical Center, Cincinnati, OH; ²Hoxworth Blood Center, Univeristy of Cincinnati, Cincinnati, OH; ³Experimental Hematology & Cancer Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH; ⁴Proram for Cell Enhancement and Technologies for Immunotherapy, Children's National Health System, Washington, DC; ⁵Depatment of Infectious Diseases, Cincinnati Children's Hospital Medical Center, Cincinnati, OH.
BackgroundViral infections remain a challenge to treat and significantly contribute to morbidity and mortality. Virus specific T cells (VSTs) have shown clinical efficacy, with minimal…
2018 American Transplant Congress
Precision (re)Phenotyping of Histologically Stable Kidney Transplants
D. Rychkov,¹ T. Sigdel,² M. Sirota,¹ M. Sarwal.²
¹Institute for Computational Health Sciences, UCSF, San Francisco, CA; ²Department of Surgery, UCSF, San Francisco, CA.
Background: Acute Rejection (AR) is the main cause of the renal failure within one year after transplantation (tx). Its earlier diagnosis is crucial for a…
2018 American Transplant Congress
Ischemia-Free Liver Transplantation for Fatty Liver Grafts in Human
W. Ju, S. Huang, Z. Guo, G. Chen, X. He.
Organ Transplant Center, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
BACKGROUND&AIMS: Fatty liver diseases have led to a continuous increase of available donor livers containing fat. Fatty liver grafts were identified as an independent risk…
2018 American Transplant Congress
Human Pancreatic ECM Scaffolds for Islet Culture and Transplantation
D. Tremmel, S. Sackett, A. Feeney, R. Maguire, J. Odorico.
Univ of Wisconsin, Madison.
Extracellular matrix (ECM) plays an important role through structural and biochemical interaction with cells. Tissue-specific ECM, attained through decellularization (decel), has been proposed in many…
2018 American Transplant Congress
Geographic Variation in Deceased Donor Kidney Waitlist Deaths after Declining an Organ Offer
F. Winterhalter,¹ S. Husain,¹ R. Patzer,² S. Pastan,² S. Mohan.¹
¹Department of Medicine/Nephrology, Columbia University, New York, NY; ²Department of Surgery, Emory University, Atlanta, GA; ³Department of Medicine, Emory University, Atlanta, GA.
Introduction: Despite the severe organ shortage, nearly 20% of all deceased donor kidneys procured in the United States are discarded annually. Wait times for kidney…
2018 American Transplant Congress
Landscape of Living Donor Kidney Transplantation with International Donors in the United States
A. Thomas,¹ M. Henderson,¹ A. Shaffer,¹ A. Massie,¹ B. Koons,² K. Lentine,³ D. Segev,¹ F. Al Ammary.¹
¹JHU, Baltimore; ²Villanova University, Villanova; ³SLU, St. Louis.
International living kidney donors (LKDs) can donate to candidates listed in the US. Recently, concerns were raised that international LKD organ-recipients might not achieve the…
2018 American Transplant Congress
Assessment of a Discharge Transplant Knowledge Quiz and Its Impact on Outcomes in Liver Transplant Recipients
H. Corbo, N. Patel, N. Pilch, C. Perez, J. Fleming, T. Harrison, J. Hardcopf, H. Meadows, B. O'Brien, J. McGillicuddy, P. Baliga, D. Taber.
Medical University of South Carolina, Charleston, SC.
The aim of this study is to determine if transplant quiz scores given prior to discharge were predictive of known patient risk factors and if…
2018 American Transplant Congress
A Propensity Matched Survival Analysis: Do Simultaneous Liver-Lung Transplant Recipients Need a Liver?
K. Freischlag,¹ B. Ezekian,² P. Schroder,² M. Mulvihill,² S. Knechtle.²
¹School of Medicine, Duke University, Durham, NC; ²Surgery, Duke University, Durham, NC.
Objective: There is debate whether simultaneous lung-liver transplant (LLT) long-term outcomes warrant allocation of two organs to a single recipient. We hypothesized that LLT recipients…