Am J Transplant, Volume 18, Suppl 3 Archives - Page 156 of 211 - ATC Abstracts

2018 American Transplant Congress
Frailty and Liver Transplantation
C. Haugen, H. Ying, C. Holscher, J. Lai, J. Garonzik-Wang, M. McAdams-DeMarco, D. Segev.
Surgery, JHU, Baltimore.
Frailty is a phenotype of decreased physiologic reserve in response to stressors. Fried frailty was developed in community dwelling older adults. Among LT waitlist patients,…
2018 American Transplant Congress
Evaluation of Immunosuppression and Infection after Desensitization in Lung Transplantation
S. Hammad, B. Ravichandran, J. Kim, D. KuKuruga, S. Cipriano, Z. Kon.
University of Maryland Medical Center, Baltimore.
Purpose: To reduce waitlist time for sensitized lung transplant recipients (LTR), our center used peri-operative desensitization for LTR with a positive virtual crossmatch (P-VXM). We…
2018 American Transplant Congress
Characteristics and Outcomes among Patients with Failed Extubation after Lung Transplantation
L. Smith, R. Kanade, L. Mahan, S. Bollineni, J. Mullins, V. Kaza, M. Mohanka, M. Wait, F. Torres, A. Banga.
University of Texas Southwestern Medical Center, Dallas, TX.
Background: Previous studies have reported an association of worse outcomes among critically ill patients with failed extubation. However there is lack of data on characteristics…
2018 American Transplant Congress
Development of a Classification of Immunosuppressant Medication Nonadherence Tool to Enable the Objective Measurement of Immunosuppressant Medication Nonadherence in Kidney Transplant Patients
D. Goodall, M. Willicombe, A. McLean, D. Taube.
Imperial College Renal and Transplant Centre, London.
IntroductionKDIGO define nonadherence to immunosuppression as a 'deviation from the prescribed medication regimen sufficient to adversely influence the regimen's intended effect'. There is however, no…
2018 American Transplant Congress
National Landscape of HIV+ Liver Transplant Candidates
A. Shaffer,¹ A. Thomas,¹ A. Massie,¹ S. Gustafson,² J. Snyder,² B. Shelton,³ R. Reed,³ J. Locke,³ D. Segev,¹ C. Durand.¹
¹JHU, Baltimore; ²SRTR, Minneapolis; ³UAB, Birmingham.
The annual number of HIV+ liver transplant (LT) recipients has increased >10-fold since 2002. However, candidate HIV-status is not collected by UNOS, and the national…
2018 American Transplant Congress
Characterization of Mycobacterium Tuberculosis Memory T Cell Subsets in Solid Organ Transplant Recipients with Previously Treated Active Tuberculosis
S. Nellimarla, Y. Natori, V. Ferreira, S. Husain, A. Humar, D. Kumar.
UHN, Toronto, Canada.
Introduction:Cell-mediated immune (CMI) responses including CD4+ and CD8+ T-cells contribute to control of Mycobacterium tuberculosis (MTb) infection. There are no data on long term TB-specific…
2018 American Transplant Congress
Infection Outcomes in Solid Organ Transplant Recipients Receiving Trimethoprim-Sulfamethoxazole as Opposed to Atovaquone for Prophylaxis
A. Drelick,¹ W. Mowrey,² G. Minamoto.³
¹Medicine, Division of Infectious Diseases, Weill Cornell Medical Center, New York, NY; ²Epidemiology & Population Health, Albert Einstein College of Medicine, Bronx, NY; ³Medicine, Division of Infectious Diseases, Montefiore Medical Center and the Albert Einstein College of Medicine, Bronx, NY.
Background: Pneumocystis jiroveci pneumonia (PJP) is an important illness amongst solid organ transplant (SOT) recipients. Trimethoprim-sulfamethoxazole (TMP-SMX) is the prophylaxis of choice based on efficacy…
2018 American Transplant Congress
Accommodation and Antibody Mediated Rejection Are Associated with Distinct TACI Polymorphisms in Kidney Transplant Recipients
M. Cascalho, M. Barbosa,¹ E. Farkash,² J. Platt.¹
¹Surgery, University of Michigan, Ann Arbor, MI; ²Pathology, University of Michigan, Ann Arbor, MI.
A. Trans-membrane Activator and CAML Interactor (TACI) gene is among the 5% most polymorphic genes in humans, TACI controls B cell differentiation and memory and…
2018 American Transplant Congress
Comparison of Temperatures for Optimal Preservation of Donor Kidneys during Oxygenated Pulsatile Perfusion
R. Bhattacharjee,¹ M. Richard-Mohamed,² A. Ruthirakanthan,³ R. Mayer,² S. Luke,³ H. Sharma,² M. TunAbraham,² B. Alharbi,² A. Haig,² P. Luke.^1,2,3
¹Matthew Mailing Centre for Translational Transplant Studies, London Health Sciences Centre, London, ON, Canada; ²Multi-Organ Transplant Program, London Health Sciences Centre, London, ON, Canada; ³Western University, Canada, London, ON, Canada.
Background. The current methods of preserving DCD renal allografts in either static cold solution or hypothermic pulsatile perfusion are unable to adequately protect the kidney…
2018 American Transplant Congress
The Superiority of Plasma Enriched Perfusate for Assessment of Donor Kidneys in an Ex-Vivo Normothermic Perfusion (EVNP) Setting
J. Palma, I. Palma, Y. Smolin, A. Perry, J. Sageshima, R. Perez.
Surgery, Transplant Division, UC Davis Health System, Sacramento, CA.
EVNP has been used to assess and repair marginal organs prior to transplantation but the optimal perfusate composition is unknown. We hypothesize that EVNP with…