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American Transplant Congress abstracts

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  • 2018 American Transplant Congress

    Pharmacogenetics of CYP3A4, CYP3A5, CYP2C8 and CYP2C19 and Their Influence on Tacrolimus Pharmacokinetics in Renal Transplant Recipients

    Z. Wang, Z. Han, J. Tao, H. Chen, L. Sun, R. Tan, M. Gu.

    Urology, The First Affiliated Hospital with Nanjing Medical University, Nanjing, Jiangsu, China.

    Tacrolimus (TAC) is an established essential immunosuppressive agent for renal transplant recipients. Our study aims to investigate the pharmacogenetics of CYP3A4, CYP3A5, CYP2C8 and CYP2C19…
  • 2018 American Transplant Congress

    Once-Daily versus Twice-Daily Tacrolimus in De Novo Living Kidney Transplantation Patients: A Multicenter, Parallel Group, Open-Label, 5-Year Randomized Noninferiority Trial

    Y. Kakuta,1 M. Okumi,1 K. Unagami,2 M. Furusawa,1 H. Ishida,1 K. Tanabe.1

    1Urology, Tokyo Women's Medical University, Tokyo, Japan; 2Nephrology, Tokyo Women's Medical University, Tokyo, Japan.

    BackgroundTacrolimus is available as twice-daily (TAC-BID) and once-daily (TAC-QD) formulations. Findings from pharmacokinetic and short-term trials are available. However, results from long-term trials are limited.We…
  • 2018 American Transplant Congress

    Long-Term Effect of BMI on Renal Function in Asian Living Kidney Donors

    J. Na,1 J. Park,1 M-.G. Yoon,1 H. Lee,2 Y. Yoon,3 K. Huh,4 M. Kim,4 S. Kim,4 Y. Kim,4 W. Han.1

    1Department of Urology, Yonsei University College of Medicine, Urological Science Institute, Seoul, Korea; 2Department of Urology, National Health Insurance Service Ilsan Hospital, Goyang-si, Korea; 3Department of Urology, Hanyang University Medical Center, Seoul, Korea; 4Department of Surgery-Transplantation, Yonsei University College of Medicine, Seoul, Korea.

    One of the targets of expanding criteria for kidney donation is BMI. As the impact of BMI differs in Asians, we studied the long-term effect…
  • 2018 American Transplant Congress

    Graft Failure in Recurrent IgA Nephropathy Following Living Kidney Transplantation: Predictive Factors Analysis of 102 Biopsies

    J. Zhang, J. Qiu, G. Chen, C. Wang, L. Chen.

    Organ Transplant Unit, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China.

    Aim To investigate the predictive factors related to graft failure in recurrentIgA nephropathy (IgAN) following living kidney transplantation. Methods We identified a series of 102…
  • 2018 American Transplant Congress

    Benefit of Patient Portal Usage in Non-High Risk Kidney Transplant Recipients

    A. Osband, J. Machan, P. Morrissey.

    Surgery, Alpert Medical School of Brown University, Providence, RI.

    Background: With widespread adoption of EHR (electronic health record), patients have access to a patient portal where they can view and thereby help monitor their…
  • 2018 American Transplant Congress

    Long-Term Follow-Up of Pediatric Kidney Recipients Who Received Alemtuzumab Induction

    D. Harriman, A. Chen, J. Rogers, R. Stratta, G. Orlando, A. South, J-.J. Lin, A. Farney.

    Surgery, Pediatrics, Cardiovascular Sciences Center, Wake Forest Baptist Medical Center, Winston-Salem, NC.

    Introduction: Experience with alemtuzumab (alem) depleting antibody induction has rarely been studied in the pediatric population, and reports that exist have limited follow-up. The purpose…
  • 2018 American Transplant Congress

    The Role of Resilience in Healthcare Transitions among Adolescent and Young Adult Kidney Transplant Recipients

    S. Quinn,1 H. Fernandez,2 T. McCorkle,1 F. Barg,3 K. Ginsburg, R. Rogers,1 S. Amaral.

    1Pediatrics, Children's Hospital of Philadelphia, Philadelphia, PA; 2Medicine, Columbia University, New York, NY; 3Family Medicine and Community Health, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA.

    Adolescent and young adult (AYA) kidney transplant (KT) recipients experience high rates of premature allograft loss during healthcare transition (HCT). There is a critical need…
  • 2018 American Transplant Congress

    Adult-Sized Kidneys Transplanted into Infants and Small Children: Outcomes after Implementing Aggressive Fluid Regimen and Medications to Support Post-Transplant Perfusion

    V. Sigurjonsdottir, P. Grimm, A. Chaudhuri.

    Lucile Packard Children's Hospital, Palo Alto, CA.

    Background: Risk of chronic graft ischemia secondary to hypoperfusion increases with greater disparity between donor and recipient size. At our center, the smallest recipients receive…
  • 2018 American Transplant Congress

    Prognostic Value and Biological Significances of Five Long Non-Coding RNAs in Hepatocellular Carcinoma

    Y. Hou,1 Z. Yu,2 N. Tam,1 S. Huang,1 J. Yang,1 L. Wu,1 Y. Ma,1 X. He.1

    1Department of Organ Transplantation, The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, Guangdong, China; 2Laboratory of Surgery, The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, Guangdong, China.

    Objectives Increasing evidence suggests that long non-coding RNA (lncRNA) plays a vital role in metastasis and development in hepatocellular carcinoma (HCC). Tumor progression severely affect…
  • 2018 American Transplant Congress

    Locoregional Treatments before Liver Transplantation for Hepatocellular Carcinoma: A Cohort Study from the European Liver Transplant Registry

    H-.C. Pommergaard, A. Rostved, R. Adam, L. Thygesen, M. Salizzoni, M. Bravo, D. Cherqui, P. De Simone, K. Boudjema, V. Mazzaferro, O. Soubrane, J. García-Valdecasas, J. Prous, A. Pinna, J. O'Grady, V. Karam, C. Duvoux, A. Rasmussen.

    Rigshospitalet, Copenhagen, Denmark; Rigshospitalet, Copenhagen, Denmark; Hôpital Universitaire Paul Brousse, Villejuif, France; National Institute of Public Health, Copenhagen, Denmark; Molinette Hospital, Turin, Italy; Hospital Virgen del Rocio, Seville, Spain; Hôpital Universitaire Paul Brousse, Villejuif, France; University of Pisa Medical School Hospital, Pisa, Italy; Hôpital Pontchaillou, Rennes, France; Istituto Nazionale Tumori, Milan, Italy; Beaujon Hospital, Clichy, France; Hospital Clínic, Barcelona, Spain; Hospital Universitari de Bellvitge, Barcelona, Spain; S. Orsola Hospital, Bologna, Italy; King's College Hospital, London, United Kingdom; Hôpital Universitaire Paul Brousse, Villejuif, France; Henri Mondor Hospital, Créteil, France; Rigshospitalet, Copenhagen, Denmark.

    PurposeLocoregional treatment while on the waiting list for liver transplantation (Ltx) for hepatocellular carcinoma (HCC) has shown to improve survival. However, effect of treatment types…
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