ATC Abstracts

American Transplant Congress abstracts

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  • 2018 American Transplant Congress

    BETA-2 Score is an Excellent Tool for Monitoring of Islet Allograft Function and Early Detection of Transplant Dysfunction

    P. Bachul,1 J. Gołębiewska,2 L. Basto,1 M. Kijek,1 N. Fillman,1 K. Cieply,1 K. Golab,1 L-.J. Wang,1 M. Tibudan,1 C. Thomas,1 A. Dębska-Ślizień,2 J. Fung,1 P. Witkowski.1

    1Surgery, University of Chicago, Chicago; 2Nephrology, Medical University of Gdańsk, Gdańsk, Poland.

    After validation of BETA-2 scores in our cohort of patients in relation to standard stimulation tests, we decided to assess the practical utility of BETA-2…
  • 2018 American Transplant Congress

    Financial Impact of Testing Standardization for Solid Organ Transplant Recipients

    S. Ugolini,2 L. Dranow,1 P. Sadler,2 M. Berry,2 J. Stehlik,1 S. Drakos,1 J. Nativi,1 E. Gilbert,1 S. McKeller,1 A. Koliopoulou,1 M. Yin,1 E. Davis,2 C. Selzman,1 O. Wever-Pinzon.1

    1Division of Cardiology, University of Utah Health, Salt Lake City, UT; 2Transplant Service Line, University of Utah Health, Salt Lake City, UT.

    Background: Infection and bone marrow suppression surveillance is common practice in transplant recipients. Ordering of inappropriate lab tests can lead to repetitive blood draws, higher…
  • 2018 American Transplant Congress

    After Action Review of Emergency Preparedness for “Hurricane Harvey” for LifeGift Houston

    R. Wood, K. Myer.

    LifeGift, Houston, TX.

    ProblemReview and evaluate a Texas based OPO's response to Hurricane Harvey. The storm hit the Texas Coast on Aug. 25, 2017 and flooded the area…
  • 2018 American Transplant Congress

    High Fibre Diet Induces Donor Specific Kidney Allograft Tolerance in Mice

    H. Wu,1,2 T. Kwan,2 Y. Loh,2 C. Wang,2 L. Macia,2 S. Alexander,2,3 S. Chadban.1,2

    1Renal Medicine, Royal Prince Alfred Hospital, Sydney, Australia; 2University of Sydney, Sydney, Australia; 3The Children Hospital at Westmead, Sydney, Australia.

    Aim: To investigate the impact of high fibre (HF) diet or dietary supplementation with the short chain fatty acid sodium acetate (SA) on kidney allograft…
  • 2018 American Transplant Congress

    Vendor-Specific Differences in Identical Strains of Mice Yield Dichotomous Result in Lung Allograft Rejection

    Y. Guo, Q. Wang, O. Onyema, A. Gelman, D. Kreisel, A. Krupnick.

    Surgery, University of Virginina, Charlottesville, VA; Surgery, Washington University in St. Louis, St. Louis, MO.

    Intro: Orthotropic transplantation of murine lung allografts has paved the way for mechanistic studies of pulmonary tolerance and rejection but discrepancies have been reported by…
  • 2018 American Transplant Congress

    Umbilical Cords-Derived Mesenchymal Stem Cells Ameliorates Hepatic Ischemia-Reperfusion Injury via Activating the AMPK-mTOR/ULK1 Signaling Pathway Enhanced Autophagy

    J. Zheng,1,2 J. Cai,1,2 L. Chen,1,2 J. Yao,1,2 K. Zeng,1,2 H. Li,1,2 Y. Zhang,1,2 Y. Yang.1,2

    1Department of Hepatic Surgery and Liver Transplantation Center of the Third Affiliated Hospital, Organ Transplantation Institute, Sun Yat-sen University, Guangzhou, Guangdong, China; 2Guangdong Key Laboratory of Liver Disease Research, Key Laboratory of Liver Disease Biotherapy and Translational Medicine of Guangdong Higher Education Institutes, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, .

    UC-MSCs induction of anti-apoptosis has been indicated to play protective roles in liver ischemia-reperfusion (I/R) model. However, the exact molecular mechanisms of UC-MSCs in hepatic…
  • 2018 American Transplant Congress

    Defining T Cell Subsets Involved in Rejection of Vascularized Composite Allografts

    G. Furtmueller,1 V. Malek,1 B. Oh,1 S. Reddy,1 M. Iglesias,1 G. Raimondi,1 G. Brandacher, D. Cooney.

    1Plastic and Reconstructive Surgery, Johns Hopkins University School of Medicine, Baltimore; 2Molecular and Comparative Pathobiology, Johns Hopkins University School of Medicine, Baltimore.

    BackgroundVascularized Composite Allotransplantation (VCA) is a clinically feasible therapeutic option for complex tissue defects. The highly immunogenic skin component of VCA represents a therapeutic challenge…
  • 2018 American Transplant Congress

    Human Atrial Natriuretic Peptide (hANP) in Cold Storage of Donation after Cardiac Death Livers: A New Tool for Protecting Vascular Endothelia?

    Y. Nigmet,1 K. Hata,1 Y. Okamura,1 I. Tamaki,1 T. Tsuruyama,2 H. Hirao,1 T. Kubota,1 J. Kusakabe,1 J. Yoshikawa,1 T. Goto,1 T. Tajima,1 H. Tanaka,1 S. Uemoto.1

    1Department of Surgery, Division of Hepato-Biliary-Pancreatic Surgery and Transplantation, Kyoto University, Kyoto, Japan; 2Center for Anatomical, Pathological, and Forensic Medical Research, Kyoto University, Kyoto, Japan.

    Aim: Current critical shortage of donor organs has led to acceptance of donation after cardiac death (DCD) livers for transplantation. Human atrial natriuretic peptide (hANP)…
  • 2018 American Transplant Congress

    Increased Length of Stay of the Donor Decreases Heart Transplant Recipient Survival

    H. Copeland,1 R. Talluri,2 A. Panos,1 R. Cochran,1 L. Creswell,1 D. Baran.3

    1Surgery, University of Mississippi Medical Center, Jackson, MS; 2Biostatistics, University of Mississippi Medical Center, Jackson, MS; 3Cardiology, Sentara Heart Hospital, Norfolk, VA.

    Purpose: We hypothesize that the longer the cardiac donor is in the hospital prior to procurement, the worse the heart transplant (tx) recipient outcome for…
  • 2018 American Transplant Congress

    Less Induction Therapy Means Fewer Early Readmissions with No Change in Rejection or Infection

    S. Kush, K. Boyle, J. Gray, S. Rega, I. Feurer, A. Shah, J. Lindenfeld.

    Vanderbilt University Medical Center, Nashville, TN.

    PURPOSE:In heart transplant, induction may allow for delay of calcineurin inhibitor initiation and renal recovery. Literature comparing lymphocyte-depleting and non-depleting induction conflicts in rejection rate…
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