Am J Transplant, Volume 18, Suppl 3 Archives - Page 147 of 211 - ATC Abstracts

2018 American Transplant Congress
Clinical and Pathological Findings in Hepatitis C Positive Renal Transplant Recipients Following Alemtuzumab Induction
S. Jonchhe, J. Husson, A. Haririan, B. Ravichandran.
University of Maryland Medical Center, Baltimore.
BackgroundHistorically, renal transplant recipients (RTRs) with chronic hepatitis C (HCV) have worse long-term outcomes. Induction with alemtuzumab (ALM) in HCV positive RTRs has been postulated…
2018 American Transplant Congress
Assessment and Outcomes of Medication Nonadherence in Pediatric Kidney Transplant Recipients: Results from the IMPACT Study
A. Dokras,¹ M. Pearl,¹ J. Peipert,¹ P. Grimm,⁴ B. Warshaw,² E. Chambers,³ A. Kirk,³ R. Ettenger.¹
¹University of California, Los Angeles, Los Angeles, CA; ²Children's Healthcare of Atlanta and Emory University, Atlanta, GA; ³Duke University, Durham, NC; ⁴Stanford University, Palo Alto, CA.
OBJECTIVE: Medication nonadherence (MNA) plays a key role in transplant (Tx) survival in pediatric kidney patients (pts). However, identification of MNA is challenging and tools…
2018 American Transplant Congress
Impact of Direct Acting Antivirals of Hepatitis C Virus Therapy on Tacrolimus Dosing Post-Liver Transplant
A. Bixby, L. Fitzgerald, R. Leek, J. Mellinger, S. Tischer.
Michigan Medicine, Ann Arbor, MI.
Background: Direct acting antivirals (DAA) have transformed hepatitis C virus (HCV) management post-liver transplant (LT). As HCV clears, hepatic metabolism improves, resulting in decreased tacrolimus…
2018 American Transplant Congress
Inflammation in Fibrotic Areas (i-IF/TA) Identifies a T Cell-Mediated Rejection Component of IF/TA with Poor Kidney Allograft Outcome
D. Viglietti, O. Aubert, J-.P. Duong Van Huyen, A. Loupy, C. Lefaucheur.
Paris Translational Research Center for Organ Transplantation, Paris, France.
Addressing the etiological heterogeneity of interstitial fibrosis in kidney allografts represents an important challenge to improve long-term transplant outcomes. We investigated the determinants, clinical and…
2018 American Transplant Congress
Genomic Modifications Associated with Epstein Barr Virus+ Post-Transplant Lymphoproliferative Disorder
M. McPherson,¹ Y. Balachandran,¹ S. Boyd,² H. Zimmermann,³ R. Trappe,³ C. Esquivel,¹ S. Krams,¹ O. Martinez.¹
¹Department of Surgery, Stanford University School of Medicine, Stanford, CA; ²Department of Pathology, Stanford University School of Medicine, Stanford, CA; ³Department of Haematology and Oncology, DIAKO Ev. Diakonie-Krankenhaus Bremen, Bremen, Germany.
Epstein Barr Virus (EBV) is nearly ubiquitous in the human population, yet EBV infection is typically asymptomatic. Nevertheless, immunosuppressed transplant recipients are susceptible to EBV+…
2018 American Transplant Congress
T-bet and STAT6 Double Deficiency Favors IL-17 Immunity after Lung Transplantation
F. Liang,¹ R. Chen,¹ Q. Chen,² J. Ochando,³ Y. Ding,¹ J. Xu.¹
¹Department of Immunology, Capital Medical University, Beijing, China; ²Department of Thoracic Surgery, Chaoyang Hospital, Beijing, China; ³Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY.
Background: The long-term success of lung transplantation is mainly limited by the development of obliterative bronchiolitis (OB) in which IL-17 plays a critical role. Direct…
2018 American Transplant Congress
Outcomes of Organ Transplantation from Donors with Cancer History
Z. Guo,¹ X. He,¹ S. Huang.¹
¹Organ Transplant Center, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China; ²Guangdong Provincial Key Laboratory of Organ Donation and Transplant Immunology, Sun Yat-sen University, Guangzhou, China; ³Guangdong Provincial International Cooperation Base of Science and Technology, Sun Yat-sen University, Guangzhou, China.
Purpose: The inherent challenges of selecting an acceptable donor for each of the increasing numbers and acuity of recipients has led programs to take increased…
2018 American Transplant Congress
First Birth after Uterus Transplant in the US
L. Johannesson, R. Gunby, Jr., T. Anthony, G. McKenna, E. Koon, A. Warren, G. dePrisco, J. Mitchell, J. Putman, K. Wallis, G. Klintmalm, G. Testa.
Baylor University Medical Center, Dallas, TX.
Introduction - Uterus Transplantation (UTx) is the first available treatment for women with Absolute Uterine Infertility (AUI). It allows the affected female to carry her…
2018 American Transplant Congress
Recombinant Thrombomodulin alpha Attenuates Kidney Graft Damage after Long Cold Ischemia Time in a Rat Kidney Transplant Model
S. Tamaki,¹ K. Shinoda,¹ M. Shimoda,² S. Morita,¹ H. Asanuma,¹ M. Oya.¹
¹Urology, Keio University School of Medicine, Tokyo, Japan; ²Pathology, Keio University School of Medicine, Tokyo, Japan.
Objectives: Thrombomodulin (TM) extensively expresses on the endothelial cells in the steady state and is known to prevent hypercoagulation via combining with thrombin and inactivating…
2018 American Transplant Congress
Long-Term Kidney Transplant Survival after Deceased-Donor Acute Kidney Injury
I. Hall, E. Akalin, J. Bromberg, M. Doshi, M. Harhay, Y. Jia, S. Mansour, S. Mohan, T. Muthumkumar, P. Reese, B. Schröppel, P. Singh, H. Thiessen-Philbrook, F. Weng, C. Parikh.
Deceased Donor Study Consortium, New Haven, CT.
Purpose: Acute kidney injury (AKI) occurs frequently in deceased donors and is associated with organ discard. Prior studies indicate an association between donor AKI and…