ATC Abstracts

American Transplant Congress abstracts

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  • 2018 American Transplant Congress

    Vascular Allografts in Renal Transplantation

    D. Reino, G. Schnickel, E. Ale, S. Ebaid, N. Agrawal, S. Rhazouani, S. Gebreselassie, A. Tzakis.

    Solid Organ Transplantation, Cleveland Clinic Florida, Weston, FL.

    Vascular allografts are used routinely in pancreas, intestine and occasionally in liver transplantation. We propose that selective use of vascular allografts may increase utilization of…
  • 2018 American Transplant Congress

    Prospective Study of Switching from Tacrolimus to Low-Dose Cyclosporine A Preserving Allograft Function in BK Virus-Associated Nephropathy

    G. Huang, X. Chen, S. Yang, C. Wang.

    Organ Transplant Center/Department of Pathology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.

    Background: Tacrolimus(Tac) -mycophenolic acid compared to cyclosporine is an independent risk factor for BK virus-associated nephropathy (BKVAN). Cyclosporine A (CsA) can inhibit BKV replication in…
  • 2018 American Transplant Congress

    Increased Gene Expression of TGF-b in Renal Transplant Patients with Polyomavirus BK Viremia

    W. Yin.

    SURGERY, Dalin Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Chia I, Taiwan; School of Medicine, Tzu Chi University, Hualien, Taiwan.

    Objective: We aimed to investigate the roles of cytokines during polyomavirus BK (BKV) reactivation in renal transplant patients.Materials and Methods: Fortyeight renal allograft recipients were…
  • 2018 American Transplant Congress

    Ethnic and Age Disparities in Outcomes among Liver Transplant Waitlist Candidates

    M. Mustian,1 S. Gray,1 B. Shelton,1 R. Reed,1 P. MacLennan,1 J. White,1 D. Eckhoff,1 R. Allman,2 J. Locke.1

    1University of Alabama at Birmingham, Birmingham; 2Department of Veterans Affairs, Washington DC.

    Background: Despite the increasing prevalence of end-stage liver disease (ESLD) in older adults, there is no consensus to determine suitability for liver transplantation (LT) in…
  • 2018 American Transplant Congress

    Hospitalization and Life Support before Liver Transplantation – Easily Available Predictors for Post-Transplant Patient Survival

    L. Wiering, P. Ritschl, M. Hippler-Benscheidt, F. Aigner, M. Biebl, D. Eurich, M. Schmelzle, I. Sauer, K. Kotsch, J. Pratschke, R. Öllinger.

    Chirurgische Klinik Campus Charité Mitte / Campus Virchow-Klinikum, Charité - Universitätsmedizin Berlin, Berlin, Germany.

    IntroductionCurrently liver allocation -in contrast to allocation of other organs- is based on urgency in many countries and survival benefit is not included. Aim of…
  • 2018 American Transplant Congress

    Clinical Utility of CMV-Specific CD8+ T-Cell Immune Competence Score in Lung and Heart-Lung Transplant Recipients at Risk of Cytomegalovirus Infection

    A. Meesing,1 R. Abraham,2 R. Razonable.1

    1Division of Infectious Diseases, Mayo Clinic, Rochester, MN; 2Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN.

    Introduction: Cytomegalovirus (CMV) is a common infection that causes significant morbidity among lung and heart-lung (LHL) transplant recipients. We determined the clinical utility of global…
  • 2018 American Transplant Congress

    Successful Desensitization with Carfilzomib-Based Regimen to Facilitate Lung Transplantation: Initial Experience

    C. Ensor,1 A. Zeevi,1 M. Mangiola,1 C. Iasella,1 M. Marrari,1 M. Morrell,1 E. Lendermon,1 S. Kilaru,1 N. Shigemura,2 J. DCunha,1 J. McDyer.1

    1University of Pittsburgh, Pittsburgh, PA; 2Temple University, Philadelphia, PA.

    Purpose:We describe the successful desensitization of highly sensitized lung transplant candidates (LTCs) using plasma exchange (PLEX),intravenous immunoglobulin G(IVIg),and carfilzomib.Methods:5-patient case series of successful desensitization of…
  • 2018 American Transplant Congress

    Preventing of Rejection of Vascularized Composite Allografts by Targeting T Cell Metabolism

    B. Oh,1 C. Cheng,2 G. Furtmüller,1 K. Donovan,1 W. Lee,1 J. Powell,2 G. Brandacher.1

    1Plastic and Reconstructive Surgery, Johns Hopkins SOM, Baltimore; 2Oncology, Johns Hopkins SOM, Baltimore.

    [Background] Upon antigen recognition and co-stimulation, T lymphocytes upregulate the metabolic machinery necessary to proliferate and sustain effector function. This metabolic reprogramming in T cells…
  • 2018 American Transplant Congress

    Evaluation of the Use of Oral Valganciclovir for the Treatment of Cytomegalovirus Infections in Pediatric Intestinal Transplant Recipients: A Single Center Review

    M. Henry, M. Vacha, M. Keck, D. Florescu.

    Nebraska Medicine, Omaha, NE.

    Purpose: To evaluate the safety and efficacy of oral valganciclovir in treating cytomegalovirus (CMV) infections in pediatric intestinal transplant recipients (pITR).Methods: This retrospective review included…
  • 2018 American Transplant Congress

    Impact of Influenza Vaccine Implementation by Transplant Pharmacy in Solid Organ Transplant Recipients

    S. Gattis,1 I. Yildirim,1,2 S. Serluco,1 C. McCracken,2 R. Liverman.1

    1Children's Healthcare of Atlanta, Atlanta, GA; 2Emory University School of Medicine, Atlanta, GA.

    Background: In solid organ transplant (SOT) recipients, influenza infection can lead to subsequent graft dysfunction and mortality. In an effort to increase vaccination rates, transplant…
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