Am J Transplant, Volume 18, Suppl 3 Archives - Page 144 of 211 - ATC Abstracts

2018 American Transplant Congress
Ultrastructural Changes in Lung Allografts: Endothelial Changes Correlate with Donor Specific Antibody & Antibody Mediated Rejection
M. Alexander, A. Bentall, P. Abell Aleff, J. Scott, A. Roden.
Mayo Clinic, Rochester, MN.
Introduction: Antibody mediated rejection (AMR) causes lung allograft (LA) injury. Challenges with C4d interpretation & lack of specific histological criteria account for difficulty in diagnosing…
2018 American Transplant Congress
Risk Factors for Postoperative Bleeding after Lung Transplantation
D. Adelmann,^1,2 S. Koch,¹ J. Menger,¹ P. Jaksch,³ M. Kurz,¹ M. Mouhieddine,¹ W. Klepetko,³ B. Steinlechner.¹
¹Department of Anesthesia, General Intensive Care and Pain Control, Medical University of Vienna, Vienna, Austria; ²Department of Anesthesia and Perioperative Care, University of California, San Francisco, San Francisco, CA; ³Medical University of Vienna, Vienna, Austria.
Bleeding complications after lung transplantation (LuTX) are associated with increased morbidity. Risk factors for postoperative bleeding complications after LuTX have not yet been reported. In…
2018 American Transplant Congress
Exploring Immunosuppressant Medication Adherence in Kidney Transplant Recipients
D. Goodall, M. Willicombe, A. McLean, D. Taube.
Imperial College Renal and Transplant Centre, London, United Kingdom.
IntroductionNonadherence to immunosuppressive medication is associated with poor outcomes following kidney transplantation. The aim of this study was to describe the beliefs, understanding and experience…
2018 American Transplant Congress
HOPE Act Deceased Organ Donors: True and False Positive Donors
C. Durand,¹ S. Seaman,¹ M. Bowring,¹ B. Doby,¹ D. Ostrander,¹ A. Redd,¹ M. Waldram,¹ S. Huprikar,² B. Haydel,² S. Lerner,² S. Florman,² N. Turgeon,³ R. Friedman-Moraco,³ A. Massie,¹ D. Segev.¹
¹JHU, Baltimore; ²Mount Sinai, New York; ³Emory, Atlanta.
HOPE in Action is a multicenter trial designed to evaluate the safety of HIV+ to HIV+ transplantation (NCT02602262). In this trial, organs from donors with…
2018 American Transplant Congress
Nontuberculous Mycobacteria in Lung Transplant Recipients: Prevalence, Risk Factors and Impact on Survival and Graft Function
D. Friedman, C. Cervera, K. Halloran, G. Tyrrell, K. Doucette.
University of Alberta, Edmonton, Canada.
BACKGROUND. Nontuberculous mycobacteria (NTM) may colonize or infect lung transplant patients. Due to differences in populations studied and geographical diversity of NTM, risk factors for…
2018 American Transplant Congress
Micafungin Prophylaxis in Liver Transplant Recipients at High Risk for Invasive Fungal Infections
A. Nolan, N. Harriott, K. Startsman.
Medstar Georgetown University Hospital, Department of Pharmacy, Washington, DC.
Purpose: This study was conducted to determine the incidence of proven or probable invasive fungal infections in the first 90 days after transplant in high…
2018 American Transplant Congress
Increase on Regulatory Cells in Kidney Transplanted Patients Presenting Donor-Specific Antibodies
G. Maciel,¹ M. Fernandes,^1,2 E. Barbosa,² H. Rodrigues,¹ N. Panajotopolus,¹ F. Agena,² E. David-Neto,² V. Coelho,¹ M. Castro.²
¹Laboratory of Immunology, São Paulo University, São Paulo, Brazil; ²Renal Transplantation Service, Clinical Hospital, São Paulo, Brazil.
The role of anti-HLA donor specific antibodies (DSA) in increasing the risk of graft rejection is known. Nevertheless, not all patients with DSA develop rejection…
2018 American Transplant Congress
Ex Vivo Bloodless Oxygen Carrier for Perfusion of DCD Kidneys during Subnormothermic Storage
P. Luke,^1,2 M. Richard-Mohamed,² A. Haig,³ R. Mayer,² S. Aquil,² A. Sener,² A. Jevnikar,^1,2 R. Bhattacharjee.^1,2
¹Matthew Mailing Centre for Translational Transplant Studies, London, ON, Canada; ²Multi-Organ Transplant Program, London Health Sciences Centre, London, ON, Canada; ³Pathology and Laboratory Medicine, London Health Sciences Centre, London, ON, Canada.
Background: Non-oxygenated static or machine perfusion in cold (4[deg]C) remains the gold standard in transplantation and an optimal method of oxygen delivery to ischemic kidneys…
2018 American Transplant Congress
Immune Modulatory Effect of Thalidomide and Dexamethasone Co-Treatment on Murine Splenocytes
E. Kim,^1,2 J. Kim,¹ K. Huh,^1,3 Y. Cho,¹ M. Kim,^1,3 Y. Kim,^1,3 B. Kim.^1,4
¹The Research Institute for Transplantation, Yonsei University College of Medicine, Seoul, Korea; ²Brain Korea 21 PLUS Project for Medical Science, Yonsei University, Seoul, Korea; ³Department of Transplantation Surgery, Yonsei University College of Medicine, Seoul, Korea; ⁴Department of Internal Medicine, Nephrology, Yonsei University College of Medicine, Seoul, Korea.
Thalidomide (TM) is known to have anti-inflammatory effects and dexamethasone (DX) is also well known to reduce inflammation and inhibit inflammatory cytokine production. Clinically, combinatorial…
2018 American Transplant Congress
Pumping Donor Kidneys Reduces DGF and Improves Allograft Survival without Affecting Rejection Rates
M. Samoylova, A. Nash, T. Brennan.
Surgery, Duke University, Durham, NC.
Recent evidence suggests that hypothermic machine perfusion of donor kidneys reduces delayed graft function (DGF), but data is sparse on its effect on allograft rejection.…