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  • 2018 American Transplant Congress

    The Preclinical Application of the Tactile Discrimination Task in Rat Models

    S-.H. Wu,1,2 C-.J. Wen,1,2 J-.J. Huang,1,2,3 Y-.C. Pei,1,2,3 C-.H. Lin,1,2,4,5 H. Cheng,1 Z-.L. Peng,1,4,5 H-.I. Yang,6 F-.C. Wei.1,2,5

    1Center for Vascularized Composite Allotransplantation, Linkou Chang Gung Memorial Hospital, Taoyuan, Taiwan; 2College of Medicine, Chang Gung University, Taoyuan, Taiwan; 3Department of Physical Medicine & Rehabilitation, Taoyuan Chang Gung Memorial Hospital, Taoyuan, Taiwan; 4Division of Trauma and Emergency Plastic Surgery, Linkou Chang Gung Memorial Hospital, Taoyuan, Taiwan; 5Division of Plastic Reconstructive Microsurgery, Linkou Chang Gung Memorial Hospital, Taoyuan, Taiwan; 6Department of Electronic Engineering, National Taipei University of Technology, Taipei, Taiwan.

    Nerve reinnervation is an important issue in the field of vascularized composite allotransplantation (VCA). However, nowadays the effective treatment for enhancing the reinnervation after the…
  • 2018 American Transplant Congress

    Screening Coccidioides Serology in Kidney Transplant Recipients: A 10-Year Cross-Sectional Analysis

    K. Phonphok,1 T. Duong,1 N. Datta,1 O. Beaird,2 J. Shaenman,2 S. Bunnapradist.1

    1Medicine-Nephrology, UCLA, Los Angeles, CA; 2Medicine-Infectious Diseases, UCLA, Los Angeles, CA.

    Introduction: Southern California is one of the endemic areas of coccidioidomycosis and patients receiving immunosuppression including kidney transplant recipients are at higher risk for dissemination…
  • 2018 American Transplant Congress

    Transplant Surgeon Perspectives on General Surgery in Transplant Recipients

    S. DiBrito, M. Bowring, S. Rasmussen, C. Haugen, C. Holscher, N. Zonnenberg, M. Henderson, D. Segev, J. Garonzik-Wang.

    Johns Hopkins, Baltimore.

    Transplant recipients (TR) often require other general surgical procedures; however, it is controversial who should provide surgical and peri-operative care for this unique population. While…
  • 2018 American Transplant Congress

    A Multi-Center Analysis of Risk Factors for Pneumocystis Pneumonia (PCP) in Solid Organ Transplant Recipients

    S. Hosseini-Moghaddam, M. Shokoohi, G. Singh, S. Dufresne, A. Jevnikar, D. Kabbani, H. Cardinal, I. Houde, M-.J. Hebert, A. Shoker, G. Prasad, A. Humar, D. Kumar.

    Medicine, London Health Sciences Centre (LHSC), London, ON, Canada.

    Introduction: Pneumocystis pneumonia (PCP) is associated with morbidity and mortality in solid organ transplant patients (SOTs). There are increasing reports of late PCP in SOT…
  • 2018 American Transplant Congress

    Factor Analysis (FA) Identifies 5 Major Axes of Kidney Transplant Biopsy (KTxBx) Pathology

    L. Hunsicker,1 J. Grande,2 J. Cecka,3 A. Matas,4 The DeKaf Consortium.

    1Int. Med., U. Iowa, Iowa City, IA; 2Pathology, Mayo Clinic, Rochester, MN; 3Immunogenetics, UCLA, Los Angeles, CA; 4Surgery, U. Minnesota, Minneapolis, MN.

    Definitions for acute rejection (ACR) and antibody mediated rejection (AMR) in KTxBx exist, but no data driven methods exist for quantitative analysis of all Banff,…
  • 2018 American Transplant Congress

    Preformed Donor-Reactive T-Cells That Persist after ABO Desensitization Independently Predict Severe Acute Cellular Rejection after Living Donor Kidney Transplantation

    T. Schachtner,1,2,3 M. Stein,2 P. Reinke.1,2

    1Nephrology and Internal Intensive Care, Charite Campus Virchow Clinic, Berlin, Germany; 2Berlin-Brandenburg Center for Regenerative Therapie (BCRT), Charite Campus Virchow Clinic, Berlin, Germany; 3Berlin Institute of Health (BIH), Charite and Max Delbrueck Center, Berlin, Germany.

    Donor-reactive T-cells have been suggested to impact allograft outcome due to a higher incidence of acute celluar rejection. These donor-reactive memory T-cells rapidly acquire effector…
  • 2018 American Transplant Congress

    Robotic Assisted Live Donor Kidney Transplantation – Technique and Outcomes

    H. Pahari,1 B. Waldman,2 J. Stracke,1 L. Malinzak,1 J. Denny,1 D. Kim,1 W. Jeong,3 M. Menon,3 A. Yoshida.1

    1Transplant Surgery, Henry Ford Hospital, Detroit, MI; 2Wayne State University, Detroit, MI; 3Urology, Henry Ford Hospital, Detroit, MI.

    Background: Robotic assisted kidney transplantation (RAKT) is now a feasible minimally invasive option in place of open living donor kidney transplant (OKT). Here, we briefly…
  • 2018 American Transplant Congress

    Frequency of Whole-Organ in Lieu of Split-Liver Transplantation over the Last Decade: Children Experienced Increased Wait Time and Death

    P. Valentino,1 S. Emre,2 L. Li,3 Y. Deng,3 G. Gan,3 D. Mulligan,2 U. Ekong,1 M. Rodriguez-Davalos.4

    1Pediatrics, Hepatology, Yale University, New Haven, CT; 2Surgery, Transplant, Yale University, New Haven, CT; 3Yale Center for Analytical Sciences, Yale University, New Haven, CT; 4Surgery, Transplant, Primary Children's Hospital, Salt Lake City, UT.

    Background: Organ shortage is a barrier in liver transplantation (LT). Split liver transplantation (SLT) increases organ utilization where a donor provides segmental grafts to 2…
  • 2018 American Transplant Congress

    Pancreas Transplant in the Elderly Patient – Should It Be Done?

    A. Gruessner,1 M. Laftavi,2 O. Pankewycz,2 R. Gruessner.1

    1SUNY Downstate Medical Center, Brooklyn, NY; 2SUNY Upstate Medical University, Syracuse, NY.

    Introduction: While kidney transplantation in the elderly diabetic patient is an accepted treatment of the secondary complication, pancreas transplants are controversial. Many centers have an…
  • 2018 American Transplant Congress

    Ablation of IRF4 Induces Transplant Tolerance by Driving Intrinsic T Cell Dysfunction

    J. Wu,1,2 H. Zhang,1 X. Shi,1 X. Xiao,1 Y. Fan,1 J. Xia,2 R. Sciammas,1,3 X. Li,1,3 W. Chen.1,3

    1Center for Immunobiology & Transplant Science, Houston Methodist Research Institute, Houston, TX; 2Department of Cardiovascular Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China; 3Department of Surgery, Weill Cornell Medical College of Cornell University, New York, NY.

    How transplant rejection is regulated on a transcriptional level remains unclear. We found that T cell-specific conditional knockout (cKO) of the transcription factor IRF4 in…
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