2018 American Transplant Congress
Risk Factors for Chronic Opioid Use after Kidney Transplantation
Opioid use is associated with increased complications, graft loss, and mortality in the kidney transplant (KTX) population. The aim of our study was to identify…2018 American Transplant Congress
Secular Trends in the Medical Complexity and Outcomes of Medicare-Insured Patients Undergoing Kidney Transplant
1Stanford University, Palo Alto, CA; 2Baylor College of Medicine, Houston, TX.
Graft and patient survival following kidney transplant (KT) are improving. The reasons for this trend are unclear. We set out to examine concurrent changes in…2018 American Transplant Congress
Anti-TIRC7 Antibody Acts Synergistically with Tacrolimus in Promoting Graft Survival in a Rat Kidney Transplant Model
Background: Induction of T cell immune response c-DNA (TIRC7) is restricted to activated lymphocytes. Modulation of TIRC7 signalling prevents immune activation specifically at the site…2018 American Transplant Congress
Outcomes after HIV+ Kidney Transplant: A HOPE in Action Study
The HIV Organ Policy Equity (HOPE) Act allows HIV-infected donor (HIV D+) organs to be transplanted into HIV+ recipients (HIV R+) under research protocols. We…2018 American Transplant Congress
Extra-Renal Effects of Estrogen Receptor-Alpha Mediate Protection from Renal Ischemia-Reperfusion Injury
Introduction: Females exhibit protection from renal ischemia-reperfusion injury (IRI) compared to males in animal models and in human kidneys transplants. Previous experiments have shown that…2018 American Transplant Congress
Class II Anti-HLA IgG2 and IgG3 DSAs Predict Poorer Outcomes in Chronic Antibody Mediated Rejection of Renal Allografts
Introduction: whilst the development of IgG3 and C1q binding de novo [dn] HLA DSAs are associated with a poor outcome in acute antibody mediated rejection,…2018 American Transplant Congress
Effects of a Multimodal Pain Control Regimen in Living Donor Laparoscopic Nephrectomies
Department of Surgery, University of Florida, Gainesville, FL.
Purpose: Evaluate the effects of a multimodal pain control regimen on length of stay (LOS), opioid consumption, pain control, and opioid/NSAID related adverse events in…2018 American Transplant Congress
Clinical Implications of Positive Crossmatch in Liver Retransplants
Surgery, University of Cincinnati, Cincinnati, OH.
BackgroundLiver transplant has been performed successfully regardless of a positive crossmatch. However, the clinical implications of a positive crossmatch in liver retransplants have not been…2018 American Transplant Congress
Geographic Variation in the Survival Benefit of Heart Transplantation
1University of Chicago, Chicago, IL; 2Northwestern University, Chicago, IL.
Purpose: Heart transplant candidate selection and treatment practices vary substantially across the US. We aimed to determine if transplant center practices modify the survival benefit…2018 American Transplant Congress
Impact of Single Nucleotide Polymorphisms on P450 Oxidoreductase and Peroxisome Proliferator-Activated Receptor alpha on Tacrolimus Pharmacokinetics in Renal Transplant Recipients
Urology, The First Affiliated Hospital with Nanjing Medical University, Nanjing, China.
The P450 oxidoreductase (POR) and peroxisome proliferator-activated receptor alpha (PPARA) genes have been reported to be associated with the activity of cytochrome P450 enzymes in…
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