2018 American Transplant Congress
Liver Transplantation Post Gastric Bypass: Surgical Complications and Outcomes
Transplant Surgery, Medstar Georgetown Transplant Institute, Washington, DC.
Introduction: Liver transplantation in patients with prior gastric bypass poses a unique challenge and may increase the risk of complications.Aim: To characterize surgical complications in…2018 American Transplant Congress
Identifying Patients with CPRA>99.95% Likely to Be Offered Deceased Donor Kidneys
Emory Transplant Center, Atlanta, GA.
The implementation of the new kidney allocation system and priority of kidneys for cPRA=100% subjects revealed a hierarchy difference in allocation to patients with cPRA=99.45%-100%.…2018 American Transplant Congress
GDF15 Preventing Renal Ischemia Reperfusion Injury
1University of Western Ontario, London, ON, Canada; 2Jilin University, ChangChun, China.
Rationale: Ischemia reperfusion (I/R) injury still remains one of main causes of early renal dysfunction in kidney transplantation. There are no effective treatments for preventing…2018 American Transplant Congress
mTORC2 Deficiency in CD11c+ dendritic Cells Promotes Acute Kidney Injury
Introduction: The role of the mammalian/mechanistic target of rapamycin (mTOR) in the pathophysiology of renal ischemia-reperfusion injury (IRI) is poorly characterized; furthermore, the influence of…2018 American Transplant Congress
Five-Year Outcomes after Randomized Treatment by Rituximab in Early Acute Antibody-Mediated Rejection in Renal Transplantation: Long Term Outcomes of the RITUX ERAH Study
Background The place of rituximab in the treatment of acute antibody-mediated rejection (ABMR) is still controversial. The French multicenter double-blind, placebo-controlled RITUX ERAH study included…2018 American Transplant Congress
The ATHENA Study: 12 Months Safety and Efficacy Data from Everolimus Combined with Tacrolimus or Cyclosporine Compared to a Standard Tacrolimus-Mycophenolate Regimen in De Novo Kidney Transplant Patients
1Athena Study Group, Germany; 2Athena Study Group, France; 3Novartis, Pharma, Germany.
The ATHENA study was set up to compare efficacy and safety of everolimus [EVR] combined with tacrolimus [TAC] or cyclosporine A [CyA] vs. a mycophenolic…2018 American Transplant Congress
Factors Related to Suboptimal Recovery of Renal Function after Living Donor Nephrectomy
Japanease Red Cross Kumamoto Hospital, Kidney Center, Kumamoto, Japan.
Introduction:Renal function of the living donor usually recovers to 60~70 percent of baseline function by compensatory hypertrophy mechanism. However, the degree of this compensatory hypertrophy…2018 American Transplant Congress
Opiate Use Trends after Liver Transplantation and the Factors Associated with Post-Transplant Opiate Dependence
1Henry Ford Hospital, Detroit, MI; 2Wayne State University SOM, Detroit, MI.
AimsOur study aims to determine predictive factors leading to post-liver transplant (LT) opioid dependence.MethodsA retrospective chart review was conducted including LT recipients from July 2013-June…2018 American Transplant Congress
CD8+ Tissue Resident Memory T Cells Are Key Effector Cells in Intestinal Transplantation Patients with GvHD
Medstar Georgetown Transplant Institute, Medstar Georgetown University Hospital, Washington, DC.
A. As the pathophysiologic role of Tissue Resident Memory T Cells (TRM) in intestinal transplantation (ITx) is unknown, this study aims to test the hypothesis…2018 American Transplant Congress
VLA-4 Blockade Inhibits Early Endogenous Memory CD8 T Cell Infiltration into Higher Risk Cardiac Allografts and Donor-Reactive T Cell Priming
Endogenous memory CD8 T cells infiltrate MHC-mismatched cardiac allografts within 24 hrs after graft reperfusion in mice. Our recent studies indicate that prolonged cold ischemic…
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