ATC Abstracts

American Transplant Congress abstracts

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  • 2018 American Transplant Congress

    Normothermic Ex-Vivo Kidney Perfusion Restores the Genetic Profile of Marginal Kidney Grafts Subjected to Warm Ischemia

    P. Urbanellis,1 M. Hamar,1 I. Linares,1 D. Kollmann,1 S. Ganesh,1 R. John,1 P. Yip,1 I. Mucsi,1 A. Ghanekar,1 D. Bagli,2 A. Konvalinka,1 D. Grant,1 L. Robinson,2 M. Selzner.1

    1University Health Network, Toronto, ON, Canada; 2SickKids Hospital, Toronto, ON, Canada.

    Background: Increasing evidence demonstrates the superiority of normothermic ex-vivo kidney perfusion (NEVKP) over cold storage (CS) for marginal renal grafts. To account for this improvement,…
  • 2018 American Transplant Congress

    The Overriding Importance of HLA-DR Donor-Specific Antibody That is Correlated to CAV after Heart Transplant

    E. Kransdorf, J. Patel, M. Kittleson, S. Dimbil, R. Levine, D. Geft, D. Chang, L. Czer, J. Kobashigawa.

    Cedars Sinai Medical Center, Los Angeles.

    Purpose: Class II donor specific anti-HLA antibodies (DSA) have been correlated to subsequent CAV development. More specifically, HLA-DQ has been most reported for CAV development.…
  • 2018 American Transplant Congress

    Congestive Hepatic Fibrosis: Correlation with Cardiac Hemodynamics and Changes after VAD or Cardiac Transplant

    S. Dhingra,1 A. Segura,3 N. Cortes-Santiago,1 M. Schwartz,5 S. Mittal,4 P. Jalal,2 G. Sood.2

    1Pathology and Immunology, Baylor College of Medicine, Houston, TX; 2Surgery, Division of Abdominal Transplantation, Baylor College of Medicine, Houston, TX; 3Cardiovasular Pathology, Texas Heart Institute, Houston, TX; 4Gastroenterology, Kelsey Seybold Clinic, Houston, TX; 5Pathology, Houston Methodist Hospital, Houston, TX.

    Background: Chronic heart failure causes chronic passive congestion of liver that can progress to advanced fibrosis. Liver biopsy is performed for assessment of fibrosis to…
  • 2018 American Transplant Congress

    Heart Transplantation in Patients with Complex Congenital Heart Disease

    M. Kittleson, J. Patel, E. Kransdorf, S. Dimbil, R. Levine, D. Geft, D. Chang, L. Czer, J. Kobashigawa, R. Garg, E. Zahn.

    Cedars Sinai Medical Center, Los Angeles.

    Purpose: As medical and surgical management of complex congenital heart disease (CCHD) improves, patients may survive into adulthood to suffer from end-stage heart failure and…
  • 2018 American Transplant Congress

    Evanescent Antibodies: A Report on the Natural History of Anti-Blood Group A2 Antibodies and Their Rapid Resolution in Patients Awaiting A2 to B Transplantation

    S. Radomski, S. Rosen-Bronson, D. Li, M. Awwad, G. Vranic, B. Javaid, P. Abrams, S. Yi, M. Cooper, A. Gilbert.

    Medstar Georgetown Transplant Institute, Medstar Georgetown University Hospital, Washington, DC.

    Introduction: Despite the benefits of A2 to B transplants, centers have been reluctant to adopt such a program due to unanswered questions including whether elevation…
  • 2018 American Transplant Congress

    Kidney Transplantation in Older Recipients: Preemptive High KDPI Kidney vs. Lower KDPI Kidney after Varying Dialysis Vintage

    B. Chopra, S. Hussain, K. Sureshkumar.

    Nephrology and Hypertension, Allegheny General Hospital, Pittsburgh, PA.

    Dialysis vintage is an independent predictor of adverse long-term kidney transplant outcomes. Transplantation of "marginal" kidneys also results in inferior outcomes. We sought to analyze…
  • 2018 American Transplant Congress

    Generation of Calculated Panel-Reactive Antibody Values Using a Reference Panel of Bone Marrow Donors

    E. Kransdorf,1 L. Gragert,2,4 M. Pando,3 N. Kaur,2 J. Patel,1 I. Kim,1 X. Zhang,1 M. Maiers,4 J. Kobashigawa.1

    1Cedars-Sinai Medical Center, Los Angeles, CA; 2Tulane University School of Medicine, New Orleans, LA; 3Baylor Scott & White, Temple, TX; 4National Marrow Donor Program, Minneapolis, MN.

    Introduction: Calculated panel-reactive antibody (CPRA) is the official metric of sensitization used by the United Network for Organ Sharing (UNOS) for kidney allocation. The reference…
  • 2018 American Transplant Congress

    Optimal Protocol for ABO Incompatible Kidney Transplantations: Analysis of 400 Cases in a Single Center Experience

    H. Kwon, Y. Kim, J. Choi, S. Shin, J. Jung, M. Cho, J. Kim, D. Han.

    Asan Medical Center, Seoul, Korea.

    This study describes the single center experience and long-term results of ABOincompatible kidney transplantation (ABO i KT).Four hundred patientswhoreceived an ABOi KT in the period…
  • 2018 American Transplant Congress

    Obesity is Associated with Increased Risk of Mortality among Living Kidney Donors

    R. Reed,1 A. Massie,2 D. Sawinski,3 P. MacLennan,1 B. Shelton,1 M. Mustian,1 D. McWilliams,1 V. Kumar,1 R. Mannon,1 R. Gaston,1 D. Segev,2 C. Lewis,1 J. Locke.1

    1University of Alabama at Birmingham, Birmingham; 2Johns Hopkins University, Baltimore; 3University of Pennsylvania, Philadelphia.

    Background: Living kidney donor (LKD) demographics have changed, and transplant centers have relaxed selection criteria to include LKDs with obesity. Recently, it has been shown…
  • 2018 American Transplant Congress

    Investigating the Variability of Fluid Resuscitation during Laparoscopic Donor Nephrectomy

    A. Williams,1 S. Kumar,2 R. Sung,1 K. Woodside,1 M. Englesbe,1 M. Alameddine,1 S. Waits.1

    1Department of Surgery, Section of Transplantation, University of Michigan, Ann Arbor, MI; 2Department of Anesthesia, University of Michigan, Ann Arbor, MI.

    Background: Under or over resuscitation during laparoscopic donor nephrectomy may have a significant effect on donor and graft outcomes. Despite the importance, no guidelines exist…
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