Am J Transplant, Volume 18, Suppl 3 Archives - Page 12 of 211 - ATC Abstracts

2018 American Transplant Congress
In Vivo Allograft Exposure to Mitochondrial DAMPs Prior to Organ Procurement Increases Graft Rejection in Mice
L. Lin, J. Wang, L. Cendales, A. Kirk, T. Brennan.
Surgery, Duke University, Durham, NC.
Mitochondria released in the setting of tissue injury are a source of damage associated molecular patterns (DAMPs) that initiate innate immune responses. We hypothesized that…
2018 American Transplant Congress
CXCR4 Inhibition Improves Donor Leukocyte Depletion during Ex Vivo Lung Perfusion
R. Davis, Q. Gao, J. Yerxa, M. Daneshmand, J. Haney, J. Klapper, M. Hartwig, A. Barbas.
Surgery, Duke University, Durham, NC.
Background: Ex vivo lung perfusion (EVLP) has emerged as a modern preservation technique, developed to evaluate candidate donor lungs in a normothermic and metabolically active…
2018 American Transplant Congress
Molecular Monitoring for Kidney Allograft Injury Following HLA Incompatible Transplantation
A. Jackson,¹ B. Iglehart,¹ S. Bagnasco,³ N. Desai.²
¹Medicine, Johns Hopkins University, Baltimore, MD; ²Surgery, Johns Hopkins University, Baltimore, MD; ³Pathology, Johns Hopkins University, Baltimore, MD.
Elevated donor derived cell free DNA (ddcfDNA) has been shown to correlate with allograft rejection following heart, lung, and kidney transplantation. We investigated whether sequential…
2018 American Transplant Congress
Diagnostic Usefulness of Medullary C4d Staining in Renal Allografts
J. Von Visger,¹ C. Von Visger, A. Satoskar,² T. Nadasdy,² J. Hemminger,² S. Brodsky.²
¹Medicine, The Ohio State University Wexner Medical Center, Columbus, OH; ²Pathology, The Ohio State University Wexner Medical Center, Columbus, OH.
Background: Detection of peritubular capillary (PTC) complement C4d on renal allograft biopsy is a histologic marker (along with serum anti-donor antibody, PTC inflammatory cells and…
2018 American Transplant Congress
Noninvasive Detection of Infection and Rejection in Renal Transplant Patients
Y. Zhou,¹ Y. Cheng,¹ T. Chiang,² G. Yang,² X. Li,² F. Zeng,² X. Wang,¹ J. Ge,² X. Hu,² H. Shi,¹ T. Wang,² L. Liu.³
¹Laboratory of Transplant Genomics, Jiangsu University Institute of Life Science, ZhenJiang, JingSu, China; ²Reasearch and Development Dpartment, SuZhou RRGene.Co.Ltd., SuZhou, JiangSu, China; ³Department of Urological Organ Transplantation, The Second XiangYa Hospital of Center South University, ChangSha, Hunan, China.
About 35% of patients would suffer actue rejection or infectionin in two years after reanl trandplantation.Cell-free DNA (cfDNA) is a new biomarker to evluate health…
2018 American Transplant Congress
The Results of Plasmapheresis and Anti-CD20 Based Desensitization without Intravenous Immunoglobulin in Positive Crossmatch Kidney Transplants
H. Kwon, Y. KIm, J. Choi, S. Shin, J. Jung, M. Cho, J. Kim, D. Han.
Asan Medical Center, Seoul, Korea.
This study examined the mid-term clinical outcomes in positive crossmatch kidney transplants (XMKT) for patients who received desensitization with plasmapheresis (PP) and anti-CD20 based regimens…
2018 American Transplant Congress
Fosfomycin vs Other Antibiotics for UTI after Kidney Transplant
O. Mgbako,¹ J-.E. Ha,¹ N. Topilow,² E. Min,¹ D. Taupin,¹ V. Tatapudi,¹ B. Gelb,¹ S. Hochman.¹
¹NYU Langone Health, New York; ²Mt Sinai West, New York.
Urinary tract infection (UTI) is a frequent infectious complication in kidney transplant recipients (KTRs). Antibiotic resistance is common among urine bacterial isolates in this population.…
2018 American Transplant Congress
Opportunistic Infections after Kidney Transplantation Are Independent Risk Factor of Kidney Allograft Loss: A Retrospective Cohort Study
P. Attias,¹ G. Melica,² E. Audureau,³ D. Boutboul,⁵ N. De Castro,⁴ S. Gallien,² P. Grimbert,¹ M. Matignon.¹
¹Nephrology Transplantation, APHP Henri Mondor, Créteil, France; ²Infectious Diseases, APHP Henri Mondor, Créteil, France; ³Public Health, APHP Henri Mondor, Créteil, France; ⁴Infectious Diseases, APHP Saint-Louis, Paris, France; ⁵Immunology, APHP Saint-Louis, Paris, France.
BackgroundCurrently, kidney allograft survival improved, use of depleting antibodies increased anddonor and recipient became older. In this context, no recent study reported epidemiology of opportunistic…
2018 American Transplant Congress
Proteinuria is Associated with Increased Risk for Cardiovascular Disease after Kidney Transplantation
R. Rahamimov,^1,2,3 M. Molcho,³ I. Vahav,³ A. Chagnac,^1,3 E. Mor,^2,3 B. Rozen-Zvi.^1,3
¹Nephrology and Hypertension, Rabin Medical Center, Petach Tikva, Israel; ²Transplantation, Rabin Medical Center, Petach Tikva, Israel; ³Sackler Faculty of Medicine, Tel- Aviv University, Tel- Aviv, Israel.
Introduction: Proteinuria is a risk factor for cardiovascular (CV) disease in the general population and occurs commonly after kidney transplantation. The association between proteinuria and…
2018 American Transplant Congress
Improved Cardiac Risk Stratification Method in Kidney Transplant Candidates.
L. Punnoose, N. Fonseka, M. Lashner, G. Mythili, S. Rao.
Cardiology, Temple University Hospital, Philadelphia.
There is a high prevalence of left ventricular systolic dysfunction (LVSD) in patient with ESRD being evaluated for kidney transplant (KT). Assessing cardiovascular reserve (CR)…