ATC Abstracts

American Transplant Congress abstracts

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  • 2018 American Transplant Congress

    HIV-Positive Donors to HIV-Positive Transplant Recipients: The Italian Experience

    P. Grossi,1 D. Dalla Gasperina,1 A. Petrolo,1 D. Lombardi,1 M. Balsamo,1 M. Moioli,2 G. Travi,2 M. Merli,2 F. Ferla,2 M. Tozzi,1 L. De Carlis,2 G. Carcano,1 M. Puoti,2 A. Nanni Costa.3

    1Medicine and Surgery, University of Insubria-ASST Sette Laghi, Varese, Italy; 2ASST Grande Ospedale Metropolitano Niguarda, Milano, Italy; 3Centro Nazionale Trapianti-ISS, Roma, Italy.

    In order to expand the availability of organs for HIV-positive patients, successful transplantation of kidneys and livers from HIV-positive donors into selected HIV-positive recipients was…
  • 2018 American Transplant Congress

    Safety and Tolerability of Therapy for Latent Tuberculosis Infection: A 16-Year Review

    Y. AlJishi, M. Bosaeed, S. Husain, C. Rotstein, A. Humar, D. Kumar.

    Transplant Infectious Diseases, UHN, Toronto, ON, Canada.

    Introduction:Screening and therapy of latent tuberculosis infection (LTBI) is recommended in transplant candidates. However, data on therapy of LTBI with fluoroquinolones are limited. We aimed…
  • 2018 American Transplant Congress

    Strongyloides Pre-Transplant Screening in Solid Organ Transplantation (SOT): Single Center Analysis

    M. Al-Obaidi,1 K. Vigil,1 R. Hasbun,1 A. De Golovine,2 V. Machicao,3 L. Ostrosky,1 S. Bynon,4 M. Nigo.1

    1Division of Infectious Diseases, UT McGovern Medical School, Houston; 2Division of Renal Disease and Hypertension, UT McGovern Medical School, Houston; 3Division of Gastroenterology, Hepatology and Nutrition, UT McGovern Medical School, Houston; 4Division of Immunology and Organ Transplantation, UT McGovern Medical School, Houston.

    Background: Strongyloides stercoralis infects about 100 million persons worldwide. In SOT, the optimal pre-transplant (Tsp) screening method (universal versus targeted) is yet to be determined.…
  • 2018 American Transplant Congress

    Preemptive B Cell Depletion Modulates Pathogenic Alloimmunity Associated with Selective Non-Activating CD28 Blockade

    N. O'Neill,1 T. Zhang,1 W. Sun,1 G. Braileanu,1 X. Cheng,1 I. Tatarov,1 W. Hassanein,1 Z. Habibabady,1 B. Cerel,1 K. Reimann,2 A. Azimzadeh,1 R. Pierson.1

    1Surgery, University of Maryland School of Medicine, Baltimore, MD; 2University of Massachusetts Medical School, Boston, MA.

    Purpose: Because anti-donor alloantibody (alloAb) elaboration is associated with chronic allograft rejection, peri-transplant B cell depletion is being explored to modulate pathogenic alloimmunity. Here, we…
  • 2018 American Transplant Congress

    Graft Perfusion with Alvespimycin, an HSP90 Inhibitor, Suppresses Acute Allograft Rejection and Prolongs Graft Survival in Murine Heart Transplantation

    T. Tanaka, T. Maehana, N. Masumori.

    Department of Urology, Sapporo Medical University, Sapporo, Japan.

    Purpose: We have previously demonstrated that administration of a heat shock protein 90 (HSP90) inhibitor to recipients prolonged the allograft survival in murine skin and…
  • 2018 American Transplant Congress

    Biliary pH, Bicarbonate and Glucose Are Suitable Biomarkers of Bile Duct Viability during Normothermic Machine Perfusion of Human Donor Livers

    A. Matton,1,2 Y. de Vries,1,2 L. Burlage,1,2 R. van Rijn,1,2 A. Gouw,3 V. de Meijer,1 T. Lisman,2 R. Porte.1

    1Department of Surgery, Section Hepatopancreatobiliary Surgery & Liver Transplantation, University Medical Center Groningen, University of Groningen, Groningen, Netherlands; 2Surgical Research Laboratory, University Medical Center Groningen, University of Groningen, Groningen, Netherlands; 3Department of Pathology, University Medical Center Groningen, University of Groningen, Groningen, Netherlands.

    Background: Normothermic machine perfusion (NMP) is rapidly making its way into the clinic and can be used for viability assessment of human donor livers prior…
  • 2018 American Transplant Congress

    Protective Effect of Ceria-Nanoparticle on Renal Ischemia Reperfusion Injury in Rats

    S-.I. Min,1 S. Kim,2 S. Kim,3 J. Ha.1

    1Surgery, Seoul National University College of Medicine, Seoul, Korea; 2Surgery, Kangwon National University Hospital, Seoul, Korea; 3Surgery, Myongji Hospital, Goyang, Korea.

    Introduction: Ischemia-reperfusion injury (IRI) is a commonly encountered problem in organ transplantation. IRI is associated with delayed graft function and acute rejection; therefore IRI adversely…
  • 2018 American Transplant Congress

    Impact of Aberrant Post-Transplant Laboratory and Blood Pressure Values on Graft Survival and Racial Disparities in Kidney Transplant

    D. Taber, Z. Su, J. Fleming, N. Pilch, A. Posadas, V. Rao, P. Mauldin, D. Dubay.

    MUSC, Charleston, SC.

    Objective: The aim of this study was to assess the impact of post-transplant lab and blood pressure (BP) clinical data on graft survival and racial…
  • 2018 American Transplant Congress

    The Value of Serum Dilution on DSA Outcome Analysis in Renal Transplantation

    W. Huang,1 L. Rebellato,2 K. Briley,2 P. Bolin,2 S. Kendrick,3 A. Maldonado,4 D. Leeser,2 C. Haisch,2 M. Everly.1

    1Terasaki Research Institute, Los Angeles, CA; 2East Carolina University, Greenville, NC; 3Eastern Nephrology Associates, Greenville, NC; 4Vidant Medical Center, Greenville, NC.

    Background: Recently, transplant centers have discussed the potential value of sera dilutions in assessment of donor specific anti-HLA antibodies (DSA). However, to date, no data…
  • 2018 American Transplant Congress

    Pilot Study of Health IT Feasibility and Impact on Quality of Life for Young Adult Kidney Transplant Recipients

    C. Blosser, R. Katz, J. Himmelfarb, N. Bansal.

    Nephrology, University of Washington, Seattle, WA.

    Background: Young adult kidney transplant recipients (KTRs) are an at-risk population and long-term survival rates are significantly lower than expected. A large majority of young…
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