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American Transplant Congress abstracts

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  • 2018 American Transplant Congress

    Transmission of Rabies through Solid Organ Transplant: A Big Issue in China

    J. Zhang, J. Lin, Y. Tian, L. Ma, W. Sun, L. Zhang, Y. Zhu, W. Qiu, L. Zhang.

    Urology, Beijing Friendship Hospital, Capital Medical University, Beijing, China.

    Purpose To summarize and analyze the clinical characteristic, prophylaxis and treatment of rabies transmitted through solid organ transplant. Methods Four recipients and their donors diagnosed…
  • 2018 American Transplant Congress

    Colistin (COL) in Solid Organ Transplant Recipients (SOTR): Friend or Foe?

    K. Neyra, C. Huauya Leuyacc, C. Kovacs, V. Athans, E. Cober.

    Cleveland Clinic, Cleveland, OH.

    Background: Data on COL use in SOTR are lacking. In other populations, high dose (HD) COL (>4.4mg/kg/day) has been associated with clinical and microbiologic cure…
  • 2018 American Transplant Congress

    Prevalence and Infection-Related Outcomes Associated with Transplant Tourism

    J. Slomovic, S. Humar, D. Kumar, A. Humar.

    Transplant Infectious Diseases, Toronto General Hospital, Toronto, ON, Canada.

    Background:Patients who receive organ transplants via transplant tourism may have a greater risk of complications. We sought to describe the infectious risks associated with this…
  • 2018 American Transplant Congress

    TACI-Ig as a Desensitization Agent in a Rat Model of Antibody Mediated Rejection

    N. Wilson,1 B. Verhoven,2 B. Boldt,2 N. Bath,2 X. Ding,1 R. Redfield III.2

    1Medicine/Nephrology, University of Wisconsin, Madison, WI; 2Surgery/Transplant, University of Wisconsin, Madison, WI.

    We examined the effect of APRIL/BLyS blockade on B cell lineages & donor specific antibody (DSA) in preclinical rodent model as a novel desensitization strategy.…
  • 2018 American Transplant Congress

    Klotho Enhances FoxO3-Mediated Manganese Superoxide Dismutase Expression by Negatively Regulating PI3K/AKT Pathway during Tacrolimus-Induced Oxidative Stress

    S. Lim,1 K. Luo,1 J. Il,1 Y. Shin,1 E. Ko,1,2 B. Chung,1,2 C. Yang.1,2

    1Transplant Research Center, The Catholic University of Korea, Seoul, Republic of Korea; 2Seoul St. Mary's Hospital, The Catholic University of Korea, Seoul, Republic of Korea.

    Mammalian members of the forkhead box protein O (FoxO) class of transcription factors are implicated in the regulation of oxidative stress, and FoxO proteins are…
  • 2018 American Transplant Congress

    Ischemia-Free Liver Transplantation in Pigs: Ischemia Reperfusion Injury is Avoidable?

    Z. Guo, X. He, Y. Tang, F. Ji, Z. Zhang, Q. Zhao, S. Huang, Z. Zhu, W. Ju, G. Chen.

    Organ Transplant Center, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China.

    BACKGROUND&AIMS: In organ transplantation, ischemia and reperfusion injury (IRI) is considered as an inevitable event and the major contributor of graft failure. Great efforts have…
  • 2018 American Transplant Congress

    Normothermic Ex Vivo Liver Perfusion Prior to Liver Transplantation Can Prevent Platelet Aggregation and Platelet Induced Sinusoidal Cell Injury

    D. Kollmann,1 I. Linares,1 S. Ganesh,1 R. Rosales,1 N. Tessandier,2 E. Boilard,2 M. Hamar,1 P. Urbanellis,1 P. Yip,3 O. Adeyi,3 M. Selzner,1 N. Selzner.1

    1Multi Organ Transplant, UHN, Toronto, Canada; 2Centre Hospitalier de l'Université Laval (CHUL), Québec, Canada; 3Laboratory Medicine and Pathobiology, UHN, Toronto, Canada.

    Background. Normothermic ex vivo liver perfusion (NEVLP) is a novel method for graft-preservation applied alternatively to static cold storage (SCS). We examined the impact of…
  • 2018 American Transplant Congress

    Malignancies in Kidney Transplant Recipients: A Long-Term Observational Study

    D. Khadzhynov, F. Halleck, F. Froehlich, L. Lehner, E. Schrezenmeyer, K. Budde, O. Staeck.

    Nephrology and Internal Intensive Care, Charite Universitaetsmedizin Berlin, Berlin, Germany.

    Background: Previous studies have shown increased incidence of malignancies in patients after kidney transplantation. However, most of the existing data on post-transplant malignancies is limited…
  • 2018 American Transplant Congress

    Impact of Renal Parenchymal Calcifications in a Cohort of Renal Transplanted Patients and Their Correlations with Long Term Graft Outcome

    C. Alfieri,1 G. Moroni,1 D. Cresseri,1 A. Regalia,1 F. Zanoni,1 V. Binda,1 M. Gandolfo,1 M. Campise,1 M. Meneghini,1 M. Ikehata,1 P. Messa.1,2

    1Nephrology Dialysis and Renal Transplantation, Fondazione IRCCS Ca Granda Ospedale Maggiore Policlinico, Milano, Italy; 2Nephrology Dialysis and Renal Transplantation, University School of Medicinw, Milan, Italy.

    Background: Renal calcifications(RC) have been described in kidney transplantation(KTx), but the aetiologyand significance of this finding are still unclear. Our aim is to evaluate the…
  • 2018 American Transplant Congress

    Proton Pump Inhibitor Use among Kidney Transplant Recipients

    N. Wilson, S. Bala, B. Concepcion.

    Vanderbilt University Medical Center, Nashville, TN.

    Background: Proton Pump Inhibitors (PPIs) have been associated with CKD and other serious adverse effects. PPI use in the transplant population has not been well-described.…
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