Am J Transplant, Volume 18, Suppl 3 Archives - Page 117 of 211 - ATC Abstracts

2018 American Transplant Congress
Modification of Macrophage Phenotype by the Magnetic Field
M. Kloc,¹ W. Chen,¹ J. Kubiak,^2,3 X. Li,¹ R. Ghobrial,¹ J. Wosik.⁴
¹Houston Methodist Research Institute, Houston, TX; ²WIHE, Warsaw, Poland; ³University of Rennes, Rennes, France; ⁴University of Houston, Houston.
Objective. Macrophages play a crucial role in health, disease and chronic rejection of transplanted organs. Chronic rejection of transplanted organs remains unresolved issue in organ…
2018 American Transplant Congress
Analyzing Transplant Medication Myths
R. Krislock, J. Brandenberger, P. Stracener, A. Weiss, K. Wipperling, C. Kuhr.
Division of Transplant, Virginia Mason Medical Center, Seattle, WA.
Patients may misconstrue the amount of medications required for transplantation, expecting to take “handfuls” of medications for life. This study aims to determine the change…
2018 American Transplant Congress
HIV-Positive Donors to HIV-Positive Transplant Recipients: The Italian Experience
P. Grossi,¹ D. Dalla Gasperina,¹ A. Petrolo,¹ D. Lombardi,¹ M. Balsamo,¹ M. Moioli,² G. Travi,² M. Merli,² F. Ferla,² M. Tozzi,¹ L. De Carlis,² G. Carcano,¹ M. Puoti,² A. Nanni Costa.³
¹Medicine and Surgery, University of Insubria-ASST Sette Laghi, Varese, Italy; ²ASST Grande Ospedale Metropolitano Niguarda, Milano, Italy; ³Centro Nazionale Trapianti-ISS, Roma, Italy.
In order to expand the availability of organs for HIV-positive patients, successful transplantation of kidneys and livers from HIV-positive donors into selected HIV-positive recipients was…
2018 American Transplant Congress
Safety and Tolerability of Therapy for Latent Tuberculosis Infection: A 16-Year Review
Y. AlJishi, M. Bosaeed, S. Husain, C. Rotstein, A. Humar, D. Kumar.
Transplant Infectious Diseases, UHN, Toronto, ON, Canada.
Introduction:Screening and therapy of latent tuberculosis infection (LTBI) is recommended in transplant candidates. However, data on therapy of LTBI with fluoroquinolones are limited. We aimed…
2018 American Transplant Congress
Strongyloides Pre-Transplant Screening in Solid Organ Transplantation (SOT): Single Center Analysis
M. Al-Obaidi,¹ K. Vigil,¹ R. Hasbun,¹ A. De Golovine,² V. Machicao,³ L. Ostrosky,¹ S. Bynon,⁴ M. Nigo.¹
¹Division of Infectious Diseases, UT McGovern Medical School, Houston; ²Division of Renal Disease and Hypertension, UT McGovern Medical School, Houston; ³Division of Gastroenterology, Hepatology and Nutrition, UT McGovern Medical School, Houston; ⁴Division of Immunology and Organ Transplantation, UT McGovern Medical School, Houston.
Background: Strongyloides stercoralis infects about 100 million persons worldwide. In SOT, the optimal pre-transplant (Tsp) screening method (universal versus targeted) is yet to be determined.…
2018 American Transplant Congress
Preemptive B Cell Depletion Modulates Pathogenic Alloimmunity Associated with Selective Non-Activating CD28 Blockade
N. O'Neill,¹ T. Zhang,¹ W. Sun,¹ G. Braileanu,¹ X. Cheng,¹ I. Tatarov,¹ W. Hassanein,¹ Z. Habibabady,¹ B. Cerel,¹ K. Reimann,² A. Azimzadeh,¹ R. Pierson.¹
¹Surgery, University of Maryland School of Medicine, Baltimore, MD; ²University of Massachusetts Medical School, Boston, MA.
Purpose: Because anti-donor alloantibody (alloAb) elaboration is associated with chronic allograft rejection, peri-transplant B cell depletion is being explored to modulate pathogenic alloimmunity. Here, we…
2018 American Transplant Congress
Graft Perfusion with Alvespimycin, an HSP90 Inhibitor, Suppresses Acute Allograft Rejection and Prolongs Graft Survival in Murine Heart Transplantation
T. Tanaka, T. Maehana, N. Masumori.
Department of Urology, Sapporo Medical University, Sapporo, Japan.
Purpose: We have previously demonstrated that administration of a heat shock protein 90 (HSP90) inhibitor to recipients prolonged the allograft survival in murine skin and…
2018 American Transplant Congress
Biliary pH, Bicarbonate and Glucose Are Suitable Biomarkers of Bile Duct Viability during Normothermic Machine Perfusion of Human Donor Livers
A. Matton,^1,2 Y. de Vries,^1,2 L. Burlage,^1,2 R. van Rijn,^1,2 A. Gouw,³ V. de Meijer,¹ T. Lisman,² R. Porte.¹
¹Department of Surgery, Section Hepatopancreatobiliary Surgery & Liver Transplantation, University Medical Center Groningen, University of Groningen, Groningen, Netherlands; ²Surgical Research Laboratory, University Medical Center Groningen, University of Groningen, Groningen, Netherlands; ³Department of Pathology, University Medical Center Groningen, University of Groningen, Groningen, Netherlands.
Background: Normothermic machine perfusion (NMP) is rapidly making its way into the clinic and can be used for viability assessment of human donor livers prior…
2018 American Transplant Congress
Protective Effect of Ceria-Nanoparticle on Renal Ischemia Reperfusion Injury in Rats
S-.I. Min,¹ S. Kim,² S. Kim,³ J. Ha.¹
¹Surgery, Seoul National University College of Medicine, Seoul, Korea; ²Surgery, Kangwon National University Hospital, Seoul, Korea; ³Surgery, Myongji Hospital, Goyang, Korea.
Introduction: Ischemia-reperfusion injury (IRI) is a commonly encountered problem in organ transplantation. IRI is associated with delayed graft function and acute rejection; therefore IRI adversely…
2018 American Transplant Congress
Impact of Aberrant Post-Transplant Laboratory and Blood Pressure Values on Graft Survival and Racial Disparities in Kidney Transplant
D. Taber, Z. Su, J. Fleming, N. Pilch, A. Posadas, V. Rao, P. Mauldin, D. Dubay.
MUSC, Charleston, SC.
Objective: The aim of this study was to assess the impact of post-transplant lab and blood pressure (BP) clinical data on graft survival and racial…