Am J Transplant, Volume 18, Suppl 3 Archives - Page 117 of 211 - ATC Abstracts

2018 American Transplant Congress
Outcomes of Liver Transplant in Sequential Eras in Patients with Polycystic Liver Disease at Various Stages of Disease
C. Desai,¹ J. Shurney,¹ P. Serrano Rodriguez,¹ A. Barritt,¹ D. Gerber,¹ A. Gruessner.²
¹University of North Carolina, Chapel Hill, NC; ²SUNY Downstate Medical Center, Brooklyn, NY.
Patients with polycystic liver disease (PLD) receive liver transplants at various time points in their disease process. Some patients receive liver transplant alone (L), some…
2018 American Transplant Congress
Disparate Risk Factors for Early and Late Death Impact Survival after Lung Transplant
C. Lehr, E. Blackstone, K. McCurry, L. Thuita, W. Tsuang, M. Valapour.
Cleveland Clinic, Cleveland, OH.
Purpose: After implementation of the lung allocation score, there has been improvement in one- and three-year survival but not in five-year survival after lung transplant…
2018 American Transplant Congress
Aquaporin 4 Blockade Alters T Cell Trafficking through a Novel Mechanism of S1PR1 Regulation
M. Nicosia,¹ R. Fan,¹ S. Miyairi,¹ A. Beavers,¹ G. Farr,² P. McGuirk,² M. Pelletier,² A. Valujskikh.¹
¹Immunology, Cleveland Clinic, Cleveland, OH; ²Aeromics LLC, Cleveland, OH.
The ubiquitous water channels aquaporins mediate a variety of immune functions. We previously demonstrated that aquaporin 4 (AQP4) is expressed by CD4 and CD8 T…
2018 American Transplant Congress
An Enhanced Educational Program for Kidney Transplant Candidates and Their Supports: Knowledge Gained but Room for Improvement
E. Clifton, A. Eshelman, D. Kim, A. Patel, P. Williams, D. Nicholson, K. Hogan, E. Rubinstein, D. Ramirez, N. Sadik, M. Jesse.
Henry Ford Health System, Detroit.
Given the complexities of transplantation, success relies on both medical and lifestyle management. Patients and their support systems require extensive education on the requirements of…
2018 American Transplant Congress
Transmission of Rabies through Solid Organ Transplant: A Big Issue in China
J. Zhang, J. Lin, Y. Tian, L. Ma, W. Sun, L. Zhang, Y. Zhu, W. Qiu, L. Zhang.
Urology, Beijing Friendship Hospital, Capital Medical University, Beijing, China.
Purpose To summarize and analyze the clinical characteristic, prophylaxis and treatment of rabies transmitted through solid organ transplant. Methods Four recipients and their donors diagnosed…
2018 American Transplant Congress
Colistin (COL) in Solid Organ Transplant Recipients (SOTR): Friend or Foe?
K. Neyra, C. Huauya Leuyacc, C. Kovacs, V. Athans, E. Cober.
Cleveland Clinic, Cleveland, OH.
Background: Data on COL use in SOTR are lacking. In other populations, high dose (HD) COL (>4.4mg/kg/day) has been associated with clinical and microbiologic cure…
2018 American Transplant Congress
Prevalence and Infection-Related Outcomes Associated with Transplant Tourism
J. Slomovic, S. Humar, D. Kumar, A. Humar.
Transplant Infectious Diseases, Toronto General Hospital, Toronto, ON, Canada.
Background:Patients who receive organ transplants via transplant tourism may have a greater risk of complications. We sought to describe the infectious risks associated with this…
2018 American Transplant Congress
TACI-Ig as a Desensitization Agent in a Rat Model of Antibody Mediated Rejection
N. Wilson,¹ B. Verhoven,² B. Boldt,² N. Bath,² X. Ding,¹ R. Redfield III.²
¹Medicine/Nephrology, University of Wisconsin, Madison, WI; ²Surgery/Transplant, University of Wisconsin, Madison, WI.
We examined the effect of APRIL/BLyS blockade on B cell lineages & donor specific antibody (DSA) in preclinical rodent model as a novel desensitization strategy.…
2018 American Transplant Congress
Klotho Enhances FoxO3-Mediated Manganese Superoxide Dismutase Expression by Negatively Regulating PI3K/AKT Pathway during Tacrolimus-Induced Oxidative Stress
S. Lim,¹ K. Luo,¹ J. Il,¹ Y. Shin,¹ E. Ko,^1,2 B. Chung,^1,2 C. Yang.^1,2
¹Transplant Research Center, The Catholic University of Korea, Seoul, Republic of Korea; ²Seoul St. Mary's Hospital, The Catholic University of Korea, Seoul, Republic of Korea.
Mammalian members of the forkhead box protein O (FoxO) class of transcription factors are implicated in the regulation of oxidative stress, and FoxO proteins are…
2018 American Transplant Congress
Ischemia-Free Liver Transplantation in Pigs: Ischemia Reperfusion Injury is Avoidable?
Z. Guo, X. He, Y. Tang, F. Ji, Z. Zhang, Q. Zhao, S. Huang, Z. Zhu, W. Ju, G. Chen.
Organ Transplant Center, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China.
BACKGROUND&AIMS: In organ transplantation, ischemia and reperfusion injury (IRI) is considered as an inevitable event and the major contributor of graft failure. Great efforts have…