ATC Abstracts

American Transplant Congress abstracts

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  • 2018 American Transplant Congress

    CMV Mismatch Still Negatively Affects Patient and Graft Survival in the Era of CMV Prophylactic and Preemptive Therapy: A Paired Kidney Analysis

    N. Leeaphorn,1 N. Garg,2 N. Thamcharoen,1 E. Khankin,1 F. Cardarelli,1 M. Pavlakis.1

    1Transplant Institute, Beth Israel Deaconess Medical Center, Boston, MA; 2Department of Medicine, Nephrology Division, University of Wisconsin School of Medicine, Madison, WI.

    Background: The impact of CMV serostatus on kidney transplant outcomes in an era when CMV prophylactic and preemptive strategies are used routinely is not clearly…
  • 2018 American Transplant Congress

    Tocilizumab Stabilizes Renal Function in Kidney Transplant Recipients with Chronic Active Antibody Mediated Rejection (CAAMR)

    S. Patel, S. Mohan, H. Fernandez, I. Batal, L. Ratner, J. Crew.

    Columbia University, New York.

    INTRO: CAAMR after kidney transplantation (KTx) is associated with rates of allograft failure approaching 50% at 2 years from injury involving T cells, B cells,…
  • 2018 American Transplant Congress

    Donor Hypothermia Outcomes in Living Kidney Transplantation

    J. Buggs,1 J. Wei,2 E. Rogers,3 R. Liu,2 V. Bowers.1

    1Transplant Surgery, Tampa General Medical Group, Tampa General Hospital, Tampa, FL; 2Molecular Pharmacology and Physiology, University of South Florida Morsani College of Medicine, Tampa, FL; 3Transplant Research, Tampa General Hospital, Tampa, FL.

    Background: The effect of donor hypothermia is known to significantly reduce the rate of delayed graft function (DGF) in cadaveric donor kidney transplantation. The effect…
  • 2018 American Transplant Congress

    Improved Renal Allograft Survival for Pre-Emptive Paediatric Renal Transplant Recipients in the United Kingdom

    M. Marlais,1 K. Martin,2 S. Marks.1

    1Paediatric Nephrology, Great Ormond Street Hospital for Children NHS Foundation Trust, London, United Kingdom; 2NHS Blood and Transplant, Bristol, United Kingdom.

    OBJECTIVESThe aim of this study was to investigate whether being on dialysis at the time of renal transplantation affected renal allograft survival in paediatric renal…
  • 2018 American Transplant Congress

    Impact of Pre-Transplant Dialysis on ESRD-Free and Patient Survival in Heart Transplant Alone and in Simultaneous Heart/Kidney Transplant Recipients: UNOS Data Analysis

    S. Akkina, A. Desai, J. Yoo, S. Hou, R. Parasuraman.

    Medicine, Loyola University, Maywood, IL.

    It is well known that chronic kidney disease has significant negative impact on post-transplant survival in heart transplant (HTx) recipients. Here we wanted to evaluate…
  • 2018 American Transplant Congress

    A Protocol for the Management of Alemtuzumab Induced Leukopenia in Kidney Transplant Recipients

    S. Hammad, B. Ravichandran, M. Crist, B. Masters.

    University of Maryland Medical Center, Baltimore.

    Purpose: Leukopenia is a common complication following alemtuzumab induction in kidney transplant recipients (KTR), often limiting its use. Our institution developed a protocol to manage…
  • 2018 American Transplant Congress

    Burden of Infectious Complications after Upper Extremity Allotransplantation: A Matched Cohort Study

    A. Conrad,1,2,3 P. Petruzzo,4,5 J. Kanitakis,6 A. Gazarian,7 L. Badet,3,8 P. Vanhems,3,9 O. Thaunat,1,3,10 E. Morelon,1,3,10 A. Sicard.1,3

    1Department of Transplantation, Nephrology and Clinical Immunology, Hospices Civils de Lyon (HCL), Lyon, France; 2Department of Infectious Diseases and Tropical Medicine, HCL, Lyon, France; 3Claude Bernard Lyon 1 University, Lyon, France; 4Department of Transplantation, HCL, Lyon, France; 5Department of Surgery, University of Cagliari, Cagliari, Italy; 6Department of Dermatology, HCL, Lyon, France; 7Clinique du Parc, Lyon, France; 8Department of Urology and Transplantation, HCL, Lyon, France; 9Infection Control and Epidemiology Unit, HCL, Lyon, France; 10INSERM U1111, International Center for Infectiology Research, Lyon, France.

    This study aimed to assess the infectious risk after upper extremity allotransplantation (UEA), a non-vital transplantation procedure requiring lifelong immunosuppression. A matched cohort study was…
  • 2018 American Transplant Congress

    Solid Organ Transplantation and Data Mining: Risk Factors for Invasive Fungal Disease in Heart Transplant Recipients

    N. Barros, D. Xie, C. Yek, T. Liu, X. Li, B. Adams-Huet, J. Martinez, S. Garg, J. Grodin, R. Morelend, A. Amin, F. Aras, J. Thibodeau, P. Mammen, M. Peltz, M. Drazner, W. Ring, R. Haley, R. La Hoz.

    UT Southwestern, Dallas, TX.

    We created a database of solid organ transplant (SOT) recipients using innovative data mining tools. This study describing the epidemiology of invasive fungal disease (IFD)…
  • 2018 American Transplant Congress

    Detection of Different Gene Expression Profiles in CD8+ T Cells from Chronic High EBV Load Carriers after Pediatric Heart and Liver Transplantation

    M. Yamada,1,2 C. Macedo,2 X. Gu,2 M. Michaels,1,2 M. Green,1,2 C. Nguyen,1,2 U. Chandran,3 B. Feingold,1,2 G. Mazariegos,1,2 D. Metes.1,2

    1Children's Hospital of Pittsburgh of UPMC, Pittsburgh, PA; 2Thomas E. Starzl Transplantation Institute, Pittsburgh, PA; 3Biomedical Informatics, University of Pittsburgh, Pittsburgh, PA.

    Background: EBV infection and post-transplant lymphoproliferative disorders (PTLD) are life-threatening complications of pediatric solid organ transplantation (Tx). The risk for PTLD varies by transplanted organ,…
  • 2018 American Transplant Congress

    Containment of Carbapenem-Resistant Enterobacteriaceae (CRE) Infections at a Solid Organ Transplant Centre

    A. Mularoni,1 G. Martucci,1 S. Gruttadauria,1 M. Campanella,1 F. Tuzzolino,1 G. Arena,1 A. Arcadipane,1 U. Palazzo,1 A. Luca,1 B. Gridelli,1 P. Grossi.2

    1ISMETT-IRCCS, Palermo, Italy; 2University of Insubria, Varese, Italy.

    Objectives The aim is to describe epidemiology and analyze the effectiveness of the intervention in CRE containment in SOT patients (pts).Methods In 2012 a taskforce…
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