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American Transplant Congress abstracts

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  • 2018 American Transplant Congress

    High Grade Cytomegalovirus Viremia Events in Solid Organ Transplant Recipients: Description and Quality Improvement

    M. Spinner,1 V. Athans,1 C. Koval.2

    1Dept. of Pharmacy, Cleveland Clinic, Cleveland, OH; 2Dept. of Infectious Diseases, Cleveland Clinic, Cleveland, OH.

    Background: High grade cytomegalovirus viremia (HGCMVV) often results in symptomatic disease requiring IV antiviral therapy and is associated with CMV recurrence and resistance. We postulated…
  • 2018 American Transplant Congress

    Hospital Readmission Patterns in the First Year after Kidney Transplantation: A Twelve-Year, Single-Center Experience

    M. Nguyen, C. Avila, J. Benedict, A. El-Hinnawi, A. Rajab, R. Pelletier, M. Henry, G. Bumgardner.

    Transplant Surgery, The Ohio State University Wexner Medical Center, Columbus, OH.

    Purpose: The majority of studies examining hospital readmissions (HR) after kidney transplantation (KT) focus on 30-day HR rates using multi-institutional data with non-uniform clinical protocols.…
  • 2018 American Transplant Congress

    Treatment Patterns and Burden among Chronic Graft versus Host Disease Patients on Second-Line Systemic Treatments Including Extracorporeal Photopheresis

    X. Huang,2 N. Joshi,1 L. Luo,1 G. Mitri,3 B. Lovelace,2 A. Pham,3 X. Gao.1

    1Pharmerit International, Bethesda, MD; 2Mallinckrodt Pharmaceuticals, Bedminster, NJ; 3Formerly of Mallinckrodt Pharmaceuticals, Bedminster, NJ.

    Extracorporeal Photopheresis (ECP) is a cell-based immunomodulatory therapeutic procedure reimbursable by the Centers for Medicare and Medicaid Services for patients with chronic Graft versus Host…
  • 2018 American Transplant Congress

    Reported Effects of the SRTR 5-Tier Rating System on US Transplant Centers

    S. Rasmussen,1 A. Thomas,1 J. Garonzik-Wang,1 M. Henderson,1 S. Stith,2 D. Segev,1 L. Hersch Nicholas.1

    1JHU, Baltimore; 2UNM, Albuquerque.

    Background: The SRTR informs patients and payers about transplant center performance. Historically, transplant programs were rated on a 3-tier scale. In 2016, the SRTR introduced…
  • 2018 American Transplant Congress

    Facial Allotransplantation: An Early Look at OPTN Data

    J. Wainright,1 L. Levin,2 L. Cendales,3 C. Wholley,1 W. Cherikh,1 D. Klassen,1 B. Pomahac.4

    1United Network for Organ Sharing, Richmond, VA; 2University of Pennsylvania, Philadelphia, PA; 3Duke University School of Medicine, Durham, NC; 4Brigham and Women's Hospital, Boston, MA.

    Craniofacial Vascularized Composite Allograft (VCA) transplantation is a developing area in the field of transplantation. Thirteen craniofacial transplants have been performed in the US since…
  • 2018 American Transplant Congress

    Experience in the Development of a Life-Supporting Large Animal Orthotopic Cardiac Xenotransplant Model

    L. DiChiacchio,1 A. Singh,1 B. Lewis,1 E. Strauss,1 P. Odonkor,1 B. Williams,1 D. Ayares,2 K. Deatrick,1 Z. Kon,1 M. Mohiuddin.1

    1Cardiac Surgery, University of Maryland Medical Center, Baltimore, MD; 2Chief Scientific Office, Revivicor, Inc., Blacksburg, VA.

    Advances in clinical immunosuppression and characterization of optimal donor genetics continue to move the field of xenotransplantation toward a clinical reality with extremely long-term survival…
  • 2018 American Transplant Congress

    MICA/B Polymorphisms and the Relationship of the Matching Degree between MICA/B and HLA of Related Donor-Recipient Pairs in Allo-HSCT

    Y. Sun, Y. Hao, J. Jin, L. Ding, F. Liang, N. Liu, J. Long, X. Zhao, Y. Xi.

    Beijing 307 Hospital, Beijing, China.

    Objective: To explore the distribution characteristics of MICA/B gene polymorphism in the Han Chinese and the relationship of the matching degree between MICA/MICB and HLA…
  • 2018 American Transplant Congress

    Patients with C-aABMR and V-Lesions in Their Renal Transplant Biopsy Have a Superior Response to Treatment

    K. Sablik, M. Clahsen-van Groningen, C. Looman, M. Betjes.

    Erasmus Medical Center, Rotterdam, Netherlands.

    Introduction Chronic active antibody mediated rejection (c-aABMR) in the renal allograft may occur with isolated arteritis. Isolated v-lesions have been associated with an inferior graft…
  • 2018 American Transplant Congress

    A Machine Learning Approach for Prediction of Delayed Graft Function in Deceased Donor Kidney Transplant Recipients

    S. Kawakita,1 A. Waterman,1,2 M. Everly.1

    1Terasaki Research Institute, Los Angeles, CA; 2Division of Nephrology, David Geffen School of Medicine at UCLA, Los Angeles, CA.

    Introduction:Delayed graft function (DGF) is an early signal of graft injury that is common in deceased donor kidney transplant (DDKT) recipients. Although we have predictive…
  • 2018 American Transplant Congress

    Sirolimus-Based, Prednisone-Free Regimen in Kidney Transplantation: Long Term Results of an Open-Label, Randomized Controlled Trial

    A. Shetty,1 B. Ho,1 V. Mas,2 Y. Kassis,1 S. Park,1 J. Leventhal,1 D. Chhabra,3 L. Gallon.1

    1Northwestern University, Chicago; 2University of Virginia, Charlottesville; 3Advocate Christ Medical Center, Chicago.

    Background: Calcineurin (CNI) nephrotoxicity is implicated in chronic allograft dysfunction and presents an argument for CNI minimizing immunosuppression. We assessed the long-term effects of CNI…
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