ATC Abstracts

American Transplant Congress abstracts

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  • 2018 American Transplant Congress

    Repeat Kidney Transplant Patients with Active Rejection Have Elevated Donor-Derived Cell-Free DNA

    S. Mehta,1 J. Chang,2 T. Hailey,1 D. Hiller,3 M. Grskovic,3 J. Yee,3 R. Mannon.1

    1University of Alabama School of Medicine, Birmingham, AL; 2Columbia University Medical Center, New York, NY; 3CareDx, Brisbane, CA.

    Purpose: Donor-derived cell-free DNA (dd-cfDNA) is an established marker of active rejection in de novo kidney transplant recipients. Here we characterize dd-cfDNA in patients who…
  • 2018 American Transplant Congress

    Serum Treatment with Fetal Bovine Serum Significantly Increases Luminex-Based HLA Antibody Assay Specificity by Reducing Heterophile Antibody Interference

    A. Jaramillo,1 J. House,1 L. Nelson,1 S. Stoll,1 R. Ridgley,1 H. Khamash.2

    1Department of Laboratory Medicine and Pathology, Mayo Clinic, Phoenix, AZ; 2Department of Medicine, Mayo Clinic, Phoenix, AZ.

    Mean fluorescence intensity (MFI) values obtained from Luminex-based HLA antibody assays are used to determine the relative strength of HLA antibodies. However, MFI values can…
  • 2018 American Transplant Congress

    Temporal Variability of IgG Subclasses

    D. Pinelli, M. Gopalakrishnan, A. Joong, P. Thrush, A. Tambur.

    Northwestern University, Chicago; Lurie Children's Hospital, Chicago.

    The temporal model of IgG subclass switching supports sequential IgG conversion; however, the diversity of previously stimulated B cells is known to shape responses in…
  • 2018 American Transplant Congress

    Efficacy of IVIG + Rituximab Desensitization Therapy on HLA Antibodies is Independent of HLA Loci

    X. Zhang,1 S. Jordan.2

    1HLA and Immunogenetics Laboratory, Comprehensive Transplant Center/ Cedars-Sinai Health Systems, Los Angeles, CA; 2Comprehensive Transplant Center, Cedars-Sinai Medical Center, Los Angeles, CA.

    Aim: Desensitization with the intravenous immunoglobulin (IVIG) and Rituximab therapy is commonly used to promote transplant of highly sensitized patients. It is suggested that HLA-DQ…
  • 2018 American Transplant Congress

    Compatible Donor and Recipient Pairs' Perspectives on Participation in Kidney Paired Donation Programs: The Emotional Implications of Indirect Donation and Transplantation

    M. Fortin,1 J. Gill,2 F. Ballesteros,1 J. Gill.2

    1CHUM, Montreal, Canada; 2UBC, Vancouver, Canada.

    The inclusion of compatible pairs in kidney paired donation (KPD) may be a strategy to increase the chance of transplantation for incompatible pairs in KPD…
  • 2018 American Transplant Congress

    Effect of Influenza Vaccine in Patients with Kidney Transplant

    K. Tsujimura,1 M. Ota,1 H. Ishida,2 K. Tanabe.2

    1Surgery, Tomishiro Central Hospital, Tomishiro-shi, Okinawa, Japan; 2Urology, Tokyo Women's Medical University, Shinjuku-ku, Tokyo, Japan.

    Objective: In this study, we aimed to evaluate the effect of influenza vaccine in kidney transplant recipients.Methods: We retrospectively studied 98 participants who underwent kidney…
  • 2018 American Transplant Congress

    Association of Body Mass Index of Kidney Transplant Recipients with Graft Function Post-Transplant

    A. Yaldo, I. Bajjoka, C. Crombez, M. Abouljoud.

    Henry Ford Transplant Institute, Detroit, MI.

    Purpose: Obese kidney transplant recipients (KTR) are known to have a significantly higher risk of delayed graft function; however, there is no data on patients…
  • 2018 American Transplant Congress

    Four Years Follow-Up in Kidney Transplant Patients with Vascular Calcifications

    L. León,1 A. Uriona,1 J. Hidalgo,1 L. Condori,1 O. Guardia,1 E. Chuluyan,2 D. Casadei.1

    1Instituto de Nefrología de Buenos Aires, Nephrology, Buenos Aires, Argentina; 2CEFYBO, UBA, CONICET, Buenos Aires, Argentina.

    Vascular calcification is associated with significant morbidity and mortality in chronic kidney diseases and kidney transplantation improves mineral metabolism. However, it is not known whether…
  • 2018 American Transplant Congress

    Impact of Vitamin D Status on Immune-Mediated Graft Function Following Kidney Transplantation

    C. Pham,1 B. Pierce,1 S. Bapat,2 S. Kuten,1 L. Moore,3 A. Gaber.3

    1Department of Pharmacy, Houston Methodist Hospital, Houston; 2College of Pharmacy, University of Houston, Houston; 3Department of Surgery, Houston Methodist Hospital, Houston.

    Ubiquitous expression of vitamin D receptors on antigen-presenting cells has sparked interest into its immunomodulatory effects. While previous literature has described the effect of vitamin…
  • 2018 American Transplant Congress

    Can Delayed Abdominal Fascia Closure Modify the Short Term Outcome after Adult Liver Transplantation?

    I. Vella,1 M. Pellicciaro,1 G. Ciancio,2 T. Manzia,1 R. Angelico,3 J. Gaynor,2 G. Iaria,1 G. Tisone,1 R. Vianna.2

    1Transplant Unit, University of Rome "Tor Vergata", Rome, Italy; 2Miami Transplant Institute, University of Miami Miller School of Medicine, Miami; 3Ospedale Pediatrico Bambino Ges[ugrave], Rome, Italy.

    BackgroundThe abdominal fascia at the end of adult liver transplantation could often represents a dangerous procedure, complicated by graft size mismatch and post reperfusion hepatic…
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