Am J Transplant, Volume 18, Suppl 3 Archives - Page 11 of 211 - ATC Abstracts

2018 American Transplant Congress
Prevalence and Impact of CYP3A5 Genomic Variances on Clinical Outcomes among African-American Kidney Transplant Recipients
A. Maldonado,¹ S. Hudson,² L. Rebellato,² T. Asempa.¹
¹Vidant Medical Center, Greenville, NC; ²East Carolina University, Greenville, NC.
Introduction: Kidney transplantation in African American (AA) recipients continues to demonstrate inferior outcomes when compared with other race/ethnicities. Contributing factors encompass differences in pharmacogenomics, and…
2018 American Transplant Congress
Early Graft Losses in National PKE Programs: Gone, but Lost Forever?
J. Verbesey,¹ A. Waterman,² J. Veale,² S. Flechner,³ B. Javaid,¹ M. Ronin,⁴ G. Hil,⁴ C. Matthew.¹
¹MedStar Georgetown Transplant Institute, Washington, DC; ²UCLA, Los Angeles, CA; ³Cleveland Clinic, Cleveland, OH; ⁴NKR, Babylon, NY.
Background: PKE increases transplants for patients who are highly sensitized or incompatible with intended living donors. Following catastrophes like primary non-function(PNF) or early graft loss,…
2018 American Transplant Congress
Impact of Donor Hepatectomy Time during Organ Procurement in Donation after Circulatory Death Liver Transplantation; The United Kingdom Experience
S. Farid, A. Magdy, D. Vijayanand, V. Upasani, S. Willis, A. Barlow, H. Ernest, A. Niaz.
St James University Hospital, Leeds, United Kingdom.
IntroductionNo data exists to evaluate the impact of hepatectomy time (HT) during donation after cardiac death (DCD) procurement on short and long-term outcomes following liver…
2018 American Transplant Congress
Outcomes of De Novo Donor Specific Antibodies in Pancreas Transplant Recipients
S. Parajuli, S. Alagusundaramoorthy, F. Aziz, N. Garg, R. Redfield, H. Sollinger, D. Kaufman, A. Djamali, J. Odorico, D. Mandelbrot.
University of Wisconsin School of Medicine and Public Health, Madison, WI.
Background: Development of de novo donor-specific antibodies (dnDSA) has detrimental effects on kidney graft survival. But, there is limited information about the relationship of dnDSA…
2018 American Transplant Congress
Unbiased Sequencing of Urine Cell-Free DNA (cfDNA) to Evaluation Urine Virome and Associated Renal Allograft Damage
D. Dadhania,¹ P. Burnham,² J. Lee,¹ C. Snopkowski,¹ C. Li,¹ S. Albakry,¹ H. Yang,¹ T. Muthukumar,¹ I. De Vlaminck,² M. Suthanthiran.¹
¹Transplantation Medicine-Nephrology, Weill Cornell Medicine, NY, NY; ²Biomedical Engineering, Cornell University, Ithaca, NY.
Intro: Virus reactivation leading to graft damage is a frequent post-kidney transplant (KTx) complication. Immunosuppressed individuals are at risk for multiple virus infections simultaneously. Current…
2018 American Transplant Congress
All DQ DSA May Not Be Equal: Comparing Outcomes between De Novo DQ DSA Specificities
M. Everly,¹ K. Briley,² A. Nguyen,¹ V. Jucaud,¹ A. Maldonado,³ C. Haisch,² P. Bolin,² S. Kendrick,⁴ H. Jones,⁴ K. McLawhorn,⁴ D. Leeser,² L. Rebellato.²
¹Terasaki Research Institute, Los Angeles; ²East Carolina University, Greenville, NC; ³Vidant Medical Center, Greenville, NC; ⁴Eastern Nephrology Associates, Greenville, NC.
It is not known if development of de novo DSA (dnDSA) to different HLA-DQ mismatches (serological) are associated with equal risk to a patient's allograft…
2018 American Transplant Congress
National Study of Living Donor Program Protocols, Processes, and Resources within U.S. Transplant Centers
D. Moore,¹ M. Dietrich,¹ P. Buerhaus,² J. Rodrigue,³ A. Minnick.¹
¹Vanderbilt University, Nashville; ²Montana State University, Bonzeman; ³Beth Israel Deaconess MC, Boston.
Purpose: There is limited research that describes living donor (LD) program processes and protocols. This study aimed to describe LD program protocols, processes, and resources…
2018 American Transplant Congress
HLA-DR4 Matching and Hepatocellular Carcinoma Recurrence after Liver Transplantation
M. Xu, S. Garcia-Aroz, N. Vachharajani, Y. Lin, W. Chapman.
Department of Surgery, Section of Abdominal Transplantation, Washington University School of Medicine, St. Louis, MO.
PURPOSE: The phenomenon of graft versus host disease after orthotopic liver transplantation (OLT) is estimated at approximately 1-2%, suggesting that under some circumstances, the graft…
2018 American Transplant Congress
TORC1 Inhibition Protects Activated Human Regulatory T Cells from Self-Inflicted Damage via Granzyme B
B. Al Dulaijan, S. Eskandari, J. Karnyski, J. Assaker, S. Cai, A. Mansouri, M. Mohamed, J. Azzi.
Transplantation Research Center, BWH, Harvard Medical School, Boston, MA.
The safety and efficacy of adoptive transfer of regulatory T cells (Tregs) are being extensively investigated in ongoing clinical trials. However, these trials have been…
2018 American Transplant Congress
Improving the Organ Donation Referral Process through Telemedicine
M. Groveman,¹ M. Perry,² I. Berman,² N. Benavides,¹ A. Friedman.¹
¹LiveOnNY, NY; ²Northwell Health, New Hyde Park.
Development of a Tele-ICU serving multiple institutions within our donor service area stimulated a collaborative performance improvement project. To improve the referral and timeliness rates…