Am J Transplant, Volume 18, Suppl 3 Archives - Page 108 of 211 - ATC Abstracts

2018 American Transplant Congress
Linking Donor Ischemia Reperfusion Injury (IRI) to Costimulatory Blockade Resistant Murine Heart Graft Rejection through Complement-Initiated Necroptosis
R. Ang, N. Chun, A. Ting, P. Heeger.
Immunology Institute, Translational Transplant Research, Icahn School of Medicine at Mount Sinai, New York, NY.
We previously showed that prolonged cold ischemic storage (CIS) of donor B6 hearts results in complement dependent, CTLA4Ig-resistant rejection in BALB/c recipients. In this system,…
2018 American Transplant Congress
How Safe is Crossing the ABO Blood Group Barrier? A Meta-Analysis to Determine the Additive Risk of ABO-Incompatible Kidney Transplantation
A. de Weerd, M. Betjes.
Nephrology and Kidney Transplantation, Erasmus Medical Center, Rotterdam, Netherlands.
Background ABO blood group-incompatible (ABOi) kidney transplantation is considered a safe procedure, with non-inferior outcomes in large cohort studies. Its contribution to living kidney transplantation…
2018 American Transplant Congress
Frailty Assessment Pilot Study in Older Kidney Transplant Recipients
B. Abdalla, B. Hale-Durbin, J. Schaenman, C. Lee, G. Danovitch.
UCLA, Los Angeles, CA.
Older patients are more often being considered for kidney transplantation, however many candidates are on the waitlist for several years. We sought to evaluate the…
2018 American Transplant Congress
Anticoagulation in Pediatric Liver Transplantation; the Pros and Cons
M. Werner,¹ R. de Kleine,¹ M. de Boer,¹ V. de Meijer,¹ R. Scheenstra,² H-.J. Verkade,² F. Bodewes,² S. Bontemps,³ T. Lisman,¹ R. Porte.¹
¹HPB Surgery & Liver Transplantation, University Medical Center Groningen, Groningen, Netherlands; ²Pediatric Gastroenterology & Hepatology, University Medical Center Groningen, Groningen, Netherlands; ³Pediatric Intensive Care, University Medical Center Groningen, Groningen, Netherlands.
Background: Hepatic artery thrombosis (HAT) and portal vein thrombosis (PVT) are serious causes of morbidity and mortality after pediatric orthotopic liver transplantation (OLT). To minimize…
2018 American Transplant Congress
Pancreas Transplant Alone (PTA) Outcome is Best in Brittle Diabetic Patients without Advanced Nephropathy
M. Laftavi,¹ A. Gruessner,² O. Pankewycz,¹ B. Kaylene,² S. Sidharth,² R. Gruessner.
¹SUNY Upstate Medical University, Syracuse, NY; ²SUNY Downstate Medical Center, Brooklyn, NY.
Introduction: Although the overall number of pancreas transplants in combination with or after a kidney transplant have declined, the number of PTA has remained relatively…
2018 American Transplant Congress
Lab Turnaround Times: A Performance Improvement Project in Post Kidney/Pancreas Transplant Clinic
M. Farrell, S. Kapadia.
Comprehensive Transplant Center, Cedars Sinai Medical Center, Los Angeles; Comprehensive Transplant Center, Cedars Sinai Medical Center, Los Angeles.
Purpose:Patients' routine labs, including immunosuppression drug levels, are drawn with each clinic visit starting at 6am.Because the drug levels are not reported by the time…
2018 American Transplant Congress
A Transcriptomic Signature in PBMC from Kidney Transplant Recipients at Baseline Predicts Early Acute Rejection
W. Zhang,¹ Z. Yi,¹ P. Cravedi,¹ L. Li,¹ K. Keung,² C. Wei,¹ M. Menon,¹ J. Dudley,¹ P. O'Connell,² B. Murphy.¹
¹Medicine, Icahn School of Medicine at Mount Sinai, New York, NY; ²Medicine, The University of Sydney, Sydney, Australia.
Background: Our multi-center study (Genomics of Chronic Allograft Rejection, GoCAR) revealed that early acute rejection (EAR, developed before 6 months post-transplant) is associated with later…
2018 American Transplant Congress
Skeletons in the Closet? An Insight into Donor Liver Discards in the US
K. Halazun, A. Rana, G. Roll, P. Tabrizian, V. Agopian, B. Samstein, R. Brown, J. Emond.
Weill Cornell Medicine, NY, NY.
Background Liver discards are poorly investigated. Among these discarded livers are potentially useable grafts that could save the lives of many of the 2500-3000 who…
2018 American Transplant Congress
Natural History and Determinants of Infectious Complications after Kidney Transplantation: A Nationwide Prospective Population Based Cohort
A. Scelma, M. Perrier, O. Lortholary, S. Girerd, C. Kerleau, V. Garrigues, F. Buron, N. Kamar, C. Legendre, Y. Bouatou, C. Lefaucheur, M. Giral, A. Loupy.
Paris Transplant Group, Paris, France.
Background: Although Infectious complications are a major cause of morbidity and mortality in KTR, little is known about their natural history and determinants at a…
2018 American Transplant Congress
Identification of Noninvasive and Mechanistically-Informative Biomarkers Predictive of Reversal of Acute Cellular Rejection (ACR) in Kidney Allografts
D. Luan,¹ J. Schwartz,² R. Ding,² T. Muthukumar,² D. Dadhania,² M. Suthanthiran.²
¹University of Michigan, Ann Arbor, MI; ²Weill Cornell Medical College, New York City, NY.
Objective: We determined whether urinary cell mRNAs predict response to anti-rejection therapy in kidney allograft recipients with Banff grade IA or higher ACR biopsies.Methods: We…