Am J Transplant, Volume 18, Suppl 3 Archives - Page 105 of 211 - ATC Abstracts

2018 American Transplant Congress
Prevalence of Metabolic Syndrome (MetS) and Insulin Resistance in Living Kidney Donors
I. Agboli, L. Moore, D. Nguyen, E. Graviss, H. Ibrahim, A. Gaber, A. Sadhu.
Houston Methodist Hospital, Houston, TX.
Living kidney donors (LD) are routinely evaluated for components of MetS such as diabetes (T2D), hypertension (HTN), and hyperlipidemia (HLD). MetS is associated with T2D,…
2018 American Transplant Congress
Belatacept-Refractory CD8⁺CD28^–CD38^hi Effector/Memory T Cells Are Targeted by mTOR Inhibition Leading to a Preferential Loss of CD40L
C. Castro Rojas,¹ A. Godarova,¹ A. Rike Shields,² R. Alloway,² M. Jordan,³ E. Woodle,² D. Hildeman.¹
¹Division of Immunobiology, Cincinnati Children's Hospital, University of Cincinnati College of Medicine, Cincinnati, OH; ²Division of Transplantation, University of Cincinnati College of Medicine, Cincinnati, OH; ³Division of Bone Marrow Transplant and Immune Deficiency, Cincinnati Children's Research Foundation, Cincinnati, OH.
Calcineurin inhibitors (CNIs) and corticosteroids (CSS) have substantial untoward side effects, most notably nephrotoxicity. Consequently, the FDA approved belatacept for maintenance immunosuppression. We recently completed…
2018 American Transplant Congress
Assesment of a Novel Chronic Kidney Disease Educational and Goal Setting Tool among Liver Transplant Recipients
R. Leek,¹ J. Park,¹ C. Koerschner,² J. Mawby,³ J. Wright Nunes,⁴ C. Sonnenday,³ P. Sharma.²
¹College of Pharmacy, University of Michigan, Ann Arbor; ²Gastroenterology and Hepatology, University of Michigan, Ann Arbor; ³Transplantation Surgery, University of Michigan, Ann Arbor; ⁴Nephrology, University of Michigan, Ann Arbor.
Background: Stage 4-5 chronic kidney disease(CKD) among liver transplant(LT) recipients is common and associated with diminished patient and graft outcomes. Our previous study showed that…
2018 American Transplant Congress
Occupational and Financial Outcomes of Directed and Non-Directed Living Liver Donors
J. Steel, M. Dulovich, K. Kingsley, S. Ganesh, O. Ola, A. Lai, S. Shen, N. Zharichenko, S. Nawaz, A. Tevar, C. Hughes, A. Humar.
Surgery, University of Pittsburgh, Pittsburgh, PA.
Background: Few transplant centers accept directed and non-directed living liver donors. The aims of this study were to compare the occupational and financial outcomes of…
2018 American Transplant Congress
Treatment and Outcomes of Orthotopic Liver Transplant Patients Secondary to Hepatitis C Virus: A Single Center Experience
T. Chen,¹ M. Moaddab,¹ B. Pierce,¹ R. Ghobrial.²
¹Department of Pharmacy, Houston Methodist Hospital, Houston, TX; ²Department of Surgery, Houston Methodist Hospital, Houston, TX.
Background: Treatment of acute cellular rejection (ACR) in patients with orthotopic liver transplantation (OLT) secondary to hepatitis C virus (HCV) remains a major challenge due…
2018 American Transplant Congress
Prostate Cancer Characteristics in Men on Immunosuppressive Medications
M. Eltemamy, A. Elshafei, A. Salah, Y. Nyame, H. Arora, A. Wee, V. Krishnamurthi, S. Jones.
Cleveland Clinic, Cleveland.
INTRODUCTION: To assess the prevalence of prostate cancer (PCa) in men receiving immunosuppressive medications undergoing transrectal ultrasound guided (TRUS) prostate biopsy.METHODS: A total of 468…
2018 American Transplant Congress
Hypothermic Oxygenated Machine Perfusion in Liver and Kidney Transplantation of Extended Criteria Donors: A Phase-1 of Clinical Trial
M. Ravaioli,¹ V. De Pace,¹ M. Cescon,¹ M. Del Gaudio,¹ V. R. Bertuzzo,¹ A. Siniscalchi,¹ A. D'Errico,² G. Comai,² G. La Manna,² A. D. Pinna.¹
¹General Surgery and Transplantation, University of Bologna Sant'Orsola - Malpighi Hospital, Bologna, Emilia Romagna, Italy; ²Experimental Diagnostic and Specialty Medicine, University of Bologna Sant'Orsola- Malpighi Hospital, Bologna, Emilia Romagna, Italy.
In the field of liver (LT) and kidney transplantation (KT), extended criteria donors (ECD) offer an additional organ source that is more vulnerable for early…
2018 American Transplant Congress
Is Kidney Transplantation Safe in Patients over 71 Years Old?
G. Andani, P. Tulissi, M. Gropuzzo, S. Crestani, C. Vallone, U. Baccarani, D. Montanaro, A. Risaliti.
Department of Kidney & Liver Transplantation, ASUIUD, Udine, Italy.
Introduction: Kidney transplantation in elderly patients is superior over dialysis as therapy for end stage renal disease (ESRD). We analyzed different parameters to evaluate patient…
2018 American Transplant Congress
Early versus Late Cytomegalovirus Prophylaxis after Kidney Transplant
M. Harris, J. Byrns, J. Gommer, M. Laub, M. Ellis.
Duke University Hospital, Durham, NC.
Background: Prophylaxis against cytomegalovirus (CMV) is recommended in high-risk patients (CMV D+/R-) and those who are CMVR+ and getting T-cell depletional therapy. It is unclear…
2018 American Transplant Congress
Early Blockade of Toll-Like Receptor 4 Reduces Ischemia-Reperfusion Injury and Improves Islet Transplantation Outcomes
C. Chang,¹ M. Lawrence,² R. Kane,¹ B. Naziruddin.³
¹Institute of Biomedical Studies, Baylor University, Waco; ²Baylor Scott & White Research Institute, Dallas; ³Baylor Simmons Transplant Institute, Dallas.
Purpose: Inflammatory damage to islets during isolation is a major hurdle for success in transplantation. We investigated the safety and therapeutic potential of pharmacological blockade…