2018 American Transplant Congress
Incidence of BK Viraemia and BK Virus Associated Nephropathy with Standard vs. Augmented Immunosuppression
Renal Transplant, University Hospitals of Coventry and Warwickshire, Coventry, United Kingdom.
Introduction:It has been long established that over-immunosuppressed state leads to BK virus reactivation. BK viraemia (BKV) can progress to BK virus associated nephropathy (BKVAN) which…2018 American Transplant Congress
Ethnic and Age Disparities in Outcomes among Liver Transplant Waitlist Candidates
1University of Alabama at Birmingham, Birmingham; 2Department of Veterans Affairs, Washington DC.
Background: Despite the increasing prevalence of end-stage liver disease (ESLD) in older adults, there is no consensus to determine suitability for liver transplantation (LT) in…2018 American Transplant Congress
Hospitalization and Life Support before Liver Transplantation – Easily Available Predictors for Post-Transplant Patient Survival
IntroductionCurrently liver allocation -in contrast to allocation of other organs- is based on urgency in many countries and survival benefit is not included. Aim of…2018 American Transplant Congress
Clinical Utility of CMV-Specific CD8+ T-Cell Immune Competence Score in Lung and Heart-Lung Transplant Recipients at Risk of Cytomegalovirus Infection
Introduction: Cytomegalovirus (CMV) is a common infection that causes significant morbidity among lung and heart-lung (LHL) transplant recipients. We determined the clinical utility of global…2018 American Transplant Congress
Successful Desensitization with Carfilzomib-Based Regimen to Facilitate Lung Transplantation: Initial Experience
1University of Pittsburgh, Pittsburgh, PA; 2Temple University, Philadelphia, PA.
Purpose:We describe the successful desensitization of highly sensitized lung transplant candidates (LTCs) using plasma exchange (PLEX),intravenous immunoglobulin G(IVIg),and carfilzomib.Methods:5-patient case series of successful desensitization of…2018 American Transplant Congress
Preventing of Rejection of Vascularized Composite Allografts by Targeting T Cell Metabolism
[Background] Upon antigen recognition and co-stimulation, T lymphocytes upregulate the metabolic machinery necessary to proliferate and sustain effector function. This metabolic reprogramming in T cells…2018 American Transplant Congress
Evaluation of the Use of Oral Valganciclovir for the Treatment of Cytomegalovirus Infections in Pediatric Intestinal Transplant Recipients: A Single Center Review
Purpose: To evaluate the safety and efficacy of oral valganciclovir in treating cytomegalovirus (CMV) infections in pediatric intestinal transplant recipients (pITR).Methods: This retrospective review included…2018 American Transplant Congress
Impact of Influenza Vaccine Implementation by Transplant Pharmacy in Solid Organ Transplant Recipients
1Children's Healthcare of Atlanta, Atlanta, GA; 2Emory University School of Medicine, Atlanta, GA.
Background: In solid organ transplant (SOT) recipients, influenza infection can lead to subsequent graft dysfunction and mortality. In an effort to increase vaccination rates, transplant…2018 American Transplant Congress
T2Candida for Diagnosis of Candidemia in Solid Organ Transplant Recipients
University of Alabama at Birmingham, Birmingham, AL.
Purpose: Candidemia is a critical contributor to morbidity following solid organ transplantation (SOT). The purpose of this study is to evaluate the T2Candida assay (T2)…2018 American Transplant Congress
Analysis of Circulating CD38+/CD138+ Plasma Cells during Development of De Novo Donor Specific Antibody Responses
CTC/Surgery, Cedars-Sinai Medical Center, Los Angeles, CA.
Purpose: Donor specific antibodies (DSA) that emerge following transplantation are indicative of allogenic sensitization and a predisposing factor for antibody mediated rejection. Though various methods…
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