2018 American Transplant Congress
Alloreactive B Cells Acquire Cell-Intrinsic Hyporesponsiveness in Tolerant Recipients
Donor-specific transplantation tolerance has long been an aspiration of clinical transplantation. Recently, we have reported that multiple mechanisms are required to reinforce profound hyporesponsiveness of…2018 American Transplant Congress
Molecular Assessment of Pre-Implantation Donor Biopsies: Effects of Prolonged Cold Ischemia Time and Development of Delayed Graft Function
Background: Deceased-donor (DD) kidneys are at higher risk for ischemia/reperfusion injury leading to increased inflammatory mediators and innate immune response. We aimed to investigate the…2018 American Transplant Congress
Impact of the Kidney Allocation System on Young Pediatric Recipients
1University of Chicago, Chicago, IL; 2Stanford University, Palo Alto, CA.
Purpose: The Kidney Allocation System (KAS) altered the priority of pediatric candidates for deceased donor kidney transplantation. Before long-term graft outcomes can be assessed, Delayed…2018 American Transplant Congress
Proton-Pump Inhibitor Utilization is Associated with Higher Rates of Clostridium difficile Infection and Hypomagnesemia after Kidney Transplant
The purpose of this project was to identify how many kidney transplant patients were taking a proton pump inhibitor (PPI) after kidney transplant at our…2018 American Transplant Congress
Inflammation in Scarred Areas (i-IF/TA): Defining the Response to Standard Treatment of T Cell-Mediated Rejection in Kidney Recipients
Paris Translational Research Center for Organ Transplantation, Paris, France.
The 2017 Banff meeting has focused on the importance of defining the potential role of i-IF/TA as a component of the T cell-mediated rejection (TCMR)…2018 American Transplant Congress
A Calculator for Kidney Transplant Waitlist Outcomes under the New Kidney Allocation System
1HCMC, Minneapolis; 2SRTR, Minneapolis; 3Univ of Minnesota, Minneapolis.
BACKGROUND: Outcomes on the kidney transplant waiting list vary markedly by region and patient characteristics, and the new kidney allocation system (KAS) changed the probability…2018 American Transplant Congress
Glycogen Synthase Kinase 3 beta Regulates Liver Inflammation Activation and Resolution by Controlling AMPK Activities
Background & Aims: Glycogen synthase kinase 3β (Gsk3β) is ubiquitously expressed with distinctive functions in different types of cells. Although its roles in regulating innate…2018 American Transplant Congress
Confirmation of the Feasibility of Ex Vivo Creation of a Novel Human Multi-Chimeric Cells Therapy for Tolerance Induction in Vascularized Composite Allotransplantation
Orthopaedics, University of Illinois at Chicago, Chicago, IL.
Purpose:Various stem cell-based therapies have been proposed as supportive treatments for patients following solid organ and vascularized composite allotransplantation (VCA) to achieve donor-specific tolerance and…2018 American Transplant Congress
Expression of the Senescence Marker P16/INK4A in Kidney Implantation Biopsies is Uniquely Associated with Poor Late Graft Function
University of Alberta, Edmonton, Canada.
With the aging donor population, accurate assessment of tissue quality of deceased donor kidneys is required to determine the intermediate and long term graft performance,…2018 American Transplant Congress
The Impact of Aorto-Iliac Calcifications on Patient and Graft Survival in Renal Transplant Recipients Using the TASC II Classification
Introduction: Kidney transplantation (KTx) is the therapy of choice in patients with end-stage renal disease. Aorto-iliac calcifications (AIC) are a relative contra-indication for KTx, even…
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