ATC Abstracts

American Transplant Congress abstracts

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  • 2018 American Transplant Congress

    Temporal Changes in Impact of HLA Mismatch among Pediatric Kidney Transplant Recipients

    J. Ruck, A. Massie, N. Desai, D. Segev, J. Garonzik-Wang.

    Johns Hopkins University School of Medicine, Baltimore, MD.

    U.S. pediatric deceased-donor kidney transplantation (pDDKT) allocation now deemphasizes HLA matching to improve equality in access to transplantation, but other national systems still consider HLA…
  • 2018 American Transplant Congress

    Informatics Tools for Mapping Molecular HLA Typing Data to UNOS Antigen Equivalencies

    N. Kaur,1 E. Kransdorf,2 M. Pando,3 M. Maiers,4 L. Gragert.1,4

    1Tulane University School of Medicine, New Orleans; 2Cedars-Sinai Heart Institute, Los Angeles; 3Baylor Scott and White, Temple; 4National Marrow Donor Program / Be The Match, Minneapolis.

    Introduction:Molecular HLA typing must be converted to antigen equivalencies for entry into the UNOS database, UNet. Maintaining an up-to-date mapping table for this purpose has…
  • 2018 American Transplant Congress

    Immunosuppression and the Risk of Dementia among Older Kidney Transplant Recipients

    M. McAdams DeMarco,1 C. Haugen,1 S. Bae,1 K. Lentine,2 D. Segev.1

    1JHU, Baltimore; 2SLU, St. Louis.

    Background: Older recipients have a high burden of dementia after kidney transplantation (KT). Factors contributing to post-KT dementia may include long-standing kidney disease, comorbid vascular…
  • 2018 American Transplant Congress

    Optimal Anti-Thymocyte Globulin Dose for Induction Immunosuppression in Kidney Transplantation

    A. Mitrokhin, J. Goldman, B. Trivedi, V. Vidyasagar, N. Vadivel, M. Hart.

    Organ Transplant Program, Swedish Medical Center, Seattle, WA.

    Anti-thymocyte globulin (ATG) is used as induction immunosuppression in kidney transplantation to prevent allograft rejection. ATG causes dose-dependent lymphocyte depletion, yet optimal dose is unknown.…
  • 2018 American Transplant Congress

    Radioisotopic Evaluation of Glomerular Filtration Rate (GFR) before and 1 Year after Kindey Donation for Transplantation: The Concept of Estimated Renal Functional Reserve (eRFR)

    V. Cantaluppi,1 G. Guglielmetti,1 M. Mora,1 A. Airoldi,1 F. Orsini,2 M. Quaglia,1 G. Sacchetti,2 C. Ronco.3

    1Nephrology and Kidney Transplantation Unit, University of Piemonte Orientale (UPO), Novara, Italy; 2Nuclear Medicine Unit, Maggiore della Carità University Hospital, Novara, Italy; 3Nephrology, Dialysis and Kidney Transplantation Unit, International Renal Research Institute (IRRIV), Vicenza, Italy.

    Kidney donors (KD) develop a partial loss of renal function defined as Acute Kidney Injury (AKI). Recovery from AKI is due to renal functional reserve…
  • 2018 American Transplant Congress

    High Prevalence of Kidney Transplant-Associated Thrombotic Microangiopathy after ABO-Incompatible Kidney Transplantation: Risk Factors, Rapid Clinical Diagnosis, and Prompt Successful Treatment

    K. Tanabe,1 M. Okumi,1 K. Unagami,2 Y. Kakuta,1 M. Inui,1 H. Ishida.1

    1Urology, Tokyo Women's Medical University, Tokyo, Japan; 2Nephrology, Tokyo Women's Medical University, Tokyo, Japan.

    BackgroundKidney transplant-associated thrombotic microangiopathy (KTA-TMA) is a multifactorial inflammatory disorder and thrombotic disease of the microvasculature. It is characterized by hemolytic anemia, thrombocytopenia, and acute…
  • 2018 American Transplant Congress

    Transplantation Tourism and Recipients Perspectives and Experience

    F. Al Rahbi, I. Al Salmi.

    The Renal Medicine Department, The Royal Hospital, Muscat, Oman.

    Background: In view of shortages of available organs, long wait times for possible transplantation and strict regulation, many patients opt for commercial transplantation. This study…
  • 2018 American Transplant Congress

    Urinary Proteomics as a Dignostic Mean for Chronic Humoral Rejection after Pediatric Kidney Transplantation

    L. Pape, A. Melk, P. Zürbig, N. Kanzelmeyer.

    Pediatric Nephrology, Hannover Medical School, Hannover, Germany; Mosaqiues Diagnostics, Hanonver, Germany.

    Chronic antibody-mediated rejection (cAMR) is the main cause of long-term graft loss and presents a diagnostic challenge in renal transplantation medicine. Late-stage diagnosis is made…
  • 2018 American Transplant Congress

    Creatinine Monitoring by Remote Blood Spot Testing in Pediatric Kidney Transplant Recipients

    J. Dickerson,1 K. Jacot,2 M. Sinkey,2 J. Smith.3

    1Laboratory Medicine, Seattle Children's, Seattle; 2Transplant, Seattle Children's, Seattle; 3Pediatrics, University of Washington, Seattle.

    Introduction: Pediatric kidney transplant patients are monitored frequently with laboratory testing to assess kidney transplant function and to optimize therapeutic drug levels. Challenges to timely…
  • 2018 American Transplant Congress

    Re-Hospitalization after Pediatric Kidney Transplantation in Steroid Avoidance Protocols

    P. Verghese, S. Chinnakotla, D. Berglund, A. Matas, B. Chavers.

    University of Minnesota, Minneapolis.

    Data on re-hospitalization rates in steroid avoidance protocols is limited. We performed a single-center, retrospective cohort study of pediatric kidney transplant recipients between 2006 and…
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