ATC Abstracts

American Transplant Congress abstracts

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  • 2018 American Transplant Congress

    Graft Perfusion with Alvespimycin, an HSP90 Inhibitor, Suppresses Acute Allograft Rejection and Prolongs Graft Survival in Murine Heart Transplantation

    T. Tanaka, T. Maehana, N. Masumori.

    Department of Urology, Sapporo Medical University, Sapporo, Japan.

    Purpose: We have previously demonstrated that administration of a heat shock protein 90 (HSP90) inhibitor to recipients prolonged the allograft survival in murine skin and…
  • 2018 American Transplant Congress

    Biliary pH, Bicarbonate and Glucose Are Suitable Biomarkers of Bile Duct Viability during Normothermic Machine Perfusion of Human Donor Livers

    A. Matton,1,2 Y. de Vries,1,2 L. Burlage,1,2 R. van Rijn,1,2 A. Gouw,3 V. de Meijer,1 T. Lisman,2 R. Porte.1

    1Department of Surgery, Section Hepatopancreatobiliary Surgery & Liver Transplantation, University Medical Center Groningen, University of Groningen, Groningen, Netherlands; 2Surgical Research Laboratory, University Medical Center Groningen, University of Groningen, Groningen, Netherlands; 3Department of Pathology, University Medical Center Groningen, University of Groningen, Groningen, Netherlands.

    Background: Normothermic machine perfusion (NMP) is rapidly making its way into the clinic and can be used for viability assessment of human donor livers prior…
  • 2018 American Transplant Congress

    Protective Effect of Ceria-Nanoparticle on Renal Ischemia Reperfusion Injury in Rats

    S-.I. Min,1 S. Kim,2 S. Kim,3 J. Ha.1

    1Surgery, Seoul National University College of Medicine, Seoul, Korea; 2Surgery, Kangwon National University Hospital, Seoul, Korea; 3Surgery, Myongji Hospital, Goyang, Korea.

    Introduction: Ischemia-reperfusion injury (IRI) is a commonly encountered problem in organ transplantation. IRI is associated with delayed graft function and acute rejection; therefore IRI adversely…
  • 2018 American Transplant Congress

    Impact of Aberrant Post-Transplant Laboratory and Blood Pressure Values on Graft Survival and Racial Disparities in Kidney Transplant

    D. Taber, Z. Su, J. Fleming, N. Pilch, A. Posadas, V. Rao, P. Mauldin, D. Dubay.

    MUSC, Charleston, SC.

    Objective: The aim of this study was to assess the impact of post-transplant lab and blood pressure (BP) clinical data on graft survival and racial…
  • 2018 American Transplant Congress

    The Value of Serum Dilution on DSA Outcome Analysis in Renal Transplantation

    W. Huang,1 L. Rebellato,2 K. Briley,2 P. Bolin,2 S. Kendrick,3 A. Maldonado,4 D. Leeser,2 C. Haisch,2 M. Everly.1

    1Terasaki Research Institute, Los Angeles, CA; 2East Carolina University, Greenville, NC; 3Eastern Nephrology Associates, Greenville, NC; 4Vidant Medical Center, Greenville, NC.

    Background: Recently, transplant centers have discussed the potential value of sera dilutions in assessment of donor specific anti-HLA antibodies (DSA). However, to date, no data…
  • 2018 American Transplant Congress

    Pilot Study of Health IT Feasibility and Impact on Quality of Life for Young Adult Kidney Transplant Recipients

    C. Blosser, R. Katz, J. Himmelfarb, N. Bansal.

    Nephrology, University of Washington, Seattle, WA.

    Background: Young adult kidney transplant recipients (KTRs) are an at-risk population and long-term survival rates are significantly lower than expected. A large majority of young…
  • 2018 American Transplant Congress

    Using the Remuzzi Score to Guide Single vs. Dual Transplantation Mitigates the Risk of Early Graft Failure

    J. Ayorinde, G. Pettigrew.

    Surgery, University of Cambridge, Cambridge, United Kingdom.

    BackgroundExpanded criteria circulatory death donors (DCD) may represent an underutilised donor pool. Our centre has used urgent pre-implantation biopsy (Remuzzi score) to guide single (SKT)…
  • 2018 American Transplant Congress

    Use of Perfusion Machine after Long Cold Ischemia Time: 3 Years Results

    A. Matos,1 L. Requião-Moura,1 E. Tonato,1 M. Souza-Durão,1,2 M. Borrelli,1 M. Nogueira,1 P. Rubio,1 A. Pacheco-Silva.1,2

    1Transplant, Hospital Israelita Albert Einstein, São Paulo, Brazil; 2Nephrology, Universidade Federal de São Paulo, São Paulo, Brazil.

    The rate of delayed graft function (DGF) in Brazil is very high, reaching 80%. This is due to the long cold ischemia time (TIF) and…
  • 2018 American Transplant Congress

    Clinical Outcomes of HIV-Infected Kidney Transplant Recipients Managed with an Early Corticosteroid Withdrawal Protocol

    A. Al Jurdi, E. Liu, M. Aull, M. Lubetsky, D. Serur, S. Kapur, T. Muthukumar.

    Weill Cornell Medicine / New York Presbyterian Hospital, New York.

    AimAssess the clinical outcomes of HIV-infected kidney transplant recipients managed with an early corticosteroid withdrawal protocol.MethodsSingle center chart review of HIV-infected kidney recipients between 2006…
  • 2018 American Transplant Congress

    Technical Challenges in Living Donor Kidney Transplantation – Diagnosis and Solutions

    R. Öllinger,1 K. Alqasim,1 F. Klein,1 N. Raschzok,1 P. Ritschl,1 S. Chopra,1 N. Otto,2 T. Denecke,3 U. Gerlach,1 M. Schmelzle,1 P. Reinke,2 J. Pratschke.1

    1Department of Surgery, Charité, Berlin, Germany; 2Department of Nephrology, Charité, Berlin, Germany; 3Department of Radiology, Charité, Berlin, Germany.

    IntroductionDue to organ scarcity living donation is becoming a major source of kidneys for transplantation. Besides medical contraindications, anatomy of the kidneys may be a…
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