2018 American Transplant Congress
Increased Expression of CEACAM1 is Cytoprotective during Ischemia-Reperfusion Injury in Human Orthotopic Liver Transplantation
Background T cell exhaustion has recently been proposed as an alternative mechanism to prevent memory development and tissue damage arising during ischemia-reperfusion injury (IRI) in…2018 American Transplant Congress
A Phase I/II, Double-Blind, Placebo-Controlled Study Assessing Safety and Efficacy of C1 Esterase Inhibitor for Prevention of Delayed Graft Function in Deceased Donor Kidney Transplant Recipients
Background: Delayed graft function (DGF)in kidney allograft recipients is traditionally defined as need for dialysis during the first week after transplantation. DGF is related to…2018 American Transplant Congress
Comprehensive Assessment of NSAID Use and Potential Nephrotoxicity Risk in Adult Veteran Kidney Transplant Recipients
Ralph H Johnson VAMC, Charleston, SC.
Background: NSAID use is generally recommended to be avoided in kidney transplantation (KTX), but there is paucity in the studies assessing their safety within this…2018 American Transplant Congress
A Novel, Dose-Adjusted Tacrolimus Intrapatient Variability Model Identifies High-Risk Kidney Transplant Recipients Better Than Existing Methodologies
Astellas Pharma Global Development, Inc., Northbrook.
Intrapatient variability (IPV) of tacrolimus trough concentration (TTC) is a risk factor for inferior transplant outcomes. However, assessing IPV is problematic, relying on fixed dose…2018 American Transplant Congress
Complement Activating HLA Class 2 Antibodies Are Associated with Poor Renal Allograft Survival; Multicentre Study
IntroductionRole of Class I and II pre-formed complement activating antibodies on renal outcomes is not well defined. In this multicentre study, we looked at the…2018 American Transplant Congress
New Factors Predicting Delayed Graft Function: A Multi-Center Cohort Study Based on Kidney Donation after Brain Death Followed by Circulatory Death
Background. Delayed graft function (DGF) is a common complication following kidney transplantation that exerts an adverse impact on graft outcomes. Donation after brain death followed…2018 American Transplant Congress
Having Your Cake and Eating It Too: An Aggressive Protocol for DSA Treatment Does Not Doom Patients to High Infectious Risk
Medstar Georgetown Transplant Institute, Medstar Georgetown University Hospital, Washington, DC.
Introduction: Antibody mediated rejection (AMR) is one of the most difficult complications to treat in kidney transplantation. We previously reported on our experience with an…2018 American Transplant Congress
CMV Viremia and Development of CMV-Specific Cytotoxic T-Cells (CMV-Tc) in Pediatric Renal Transplant Recipients
Comprehensive Transplant Center, Cedars-Sinai Medical Center, Los Angeles, CA.
Background: The use of lymphocyte depleting agents (LDA) for induction immunosuppression among renal transplant (tx) recipients raises concern for the increased susceptibility to viral infections,…2018 American Transplant Congress
Impact of Cigarette Smoking on Living Kidney Donor
Introduction: Smoking is known to result in the decline of renal allograft function and survival of recipients. However, effect of smoking on living kidney donor…2018 American Transplant Congress
Results of UNOS Survey on Diagnosis, Treatment and Follow-Up Evaluation of Clinical and Sub-Clinical TCMR and ABMR in Kidney Transplant Recipients
1University of Pittsburgh Medical Center, Pittsburgh; 2UNOS, Richmond.
Management strategies for treatment of rejection post ktx vary among centers. Controlling minor degrees of inflammation can prevent chronic allograft scarring. To study the diverse…
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