VCA Deceased Donor Solid Organ Yield
1Research, UNOS, Richmond, VA, 2Policy and Community Relations, UNOS, Richmond, VA, 3New England Donor Services, Waltham, MA, 4Professional Education, UNOS, Richmond, VA, 5Office of Chief Medical Officer, UNOS, Richmond, VA
Meeting: 2019 American Transplant Congress
Abstract number: A72
Keywords: Donation
Session Information
Session Name: Poster Session A: Basic & Clinical Science – VCA
Session Type: Poster Session
Date: Saturday, June 1, 2019
Session Time: 5:30pm-7:30pm
Presentation Time: 5:30pm-7:30pm
Location: Hall C & D
*Purpose: VCA provides life-changing transplants, but the perception exists that VCA procurement complicates the donation process and impedes solid organ donation. This study examined the predicted vs. observed number of solid organs donated by VCA donors.
*Methods: The cohort included VCA donors in the U.S. 1/1/2008-12/31/17 (n=51). We used OPTN data to calculate observed-to-expected (O:E) yield ratios with 2017 SRTR donor yield models.
*Results: O:E ratio for overall organ yield was as predicted. When analyzed by VCA type, donors of unilateral upper limbs, face, or abdominal wall had overall organ yields that were as predicted. Bilateral upper limb and uterus donors had higher than expected organ yields (Figure 1). Almost all VCA donors’ livers (48/51; 94.1%) and kidneys (92/102; 90.2%) were transplanted. Fewer hearts (28/51; 54.9%), lungs (46/102; 45.1%), pancreata (15/51; 29.4%), and intestines (3/51; 5.9%) were transplanted (Figure 2). Liver and lung yields were greater than expected. We found organ yields for kidney and pancreas as predicted. Yields for hearts were lower than predicted, with total expected mean yield=31.4 vs. total actual yield=28. Of the 9 recovered VCA donors who had an expected heart yield greater than 0.5 (>50% chance a similar donor would donate a heart), but were not heart donors, 6 (66.7%) had an LV ejection fraction less than 40, suggesting they were not suitable heart donors.
*Conclusions: Solid organ recovery among VCA donors was as predicted or better for most organs, suggesting that VCA donation does not compromise transplantation of abdominal and thoracic organs.
To cite this abstract in AMA style:
Wainright J, Vece G, Wholley C, Rosendale J, Cherikh W, Curran C, Robinson A, Battista DDi, Klassen D. VCA Deceased Donor Solid Organ Yield [abstract]. Am J Transplant. 2019; 19 (suppl 3). https://atcmeetingabstracts.com/abstract/vca-deceased-donor-solid-organ-yield/. Accessed November 22, 2024.« Back to 2019 American Transplant Congress