*Purpose: Equipping patients and donors with in-depth information about kidney paired donation (KPD) processes, risks, benefits, and protections is necessary for informed decision-making and comfort. Since the National Kidney Registry (NKR) was founded, it has completed 3600 paired exchanges through a network of 85 transplant centers. This study examined the specific educational content domains discussed with recipients (7 topics) and potential donors (24 topics) and compared the content delivered in NKR-centers with high (>62 KPDs) and low KPD (≤62 KPDs) volumes.

*Methods: 90 transplant coordinators, 68% of whom were dedicated KPD coordinators, from 68 centers (80% response rate) completed an educational practices survey (86% female, 82% white).

*Results: For potential donors, >80% discussed what NKR does, definitions of key KPD terms (e.g., chain, bridge donor), how matching works, the benefits and risks of KPD, the process of transporting kidneys, and long-term follow-up requirements (Table). For recipients, nearly all providers (>80%) discussed the opportunity of KPD when their donor was incompatible, the need to wait for a match, and the possibility of not meeting their actual donor; fewer covered payment of complex, out of state costs or financial protections.

*Conclusions: Compared to centers with low KPD volumes, centers with higher KPD volumes were more likely to discuss and educate potential donors about 8 KPD topics compared to lower volume centers (Table). While high volume centers are doing a more comprehensive job educating about KPD topics, greater standardization of KPD educational content for both potential donors and recipients across all NKR-affiliated centers is still needed.

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