ATC Abstracts

American Transplant Congress abstracts

  • Home
  • Meetings Archive
    • 2022 American Transplant Congress
    • 2021 American Transplant Congress
    • 2020 American Transplant Congress
    • 2019 American Transplant Congress
    • 2018 American Transplant Congress
    • 2017 American Transplant Congress
    • 2016 American Transplant Congress
    • 2015 American Transplant Congress
    • 2013 American Transplant Congress
  • Keyword Index
  • Resources
    • 2021 Resources
    • 2016 Resources
      • 2016 Welcome Letter
      • ATC 2016 Program Planning Committees
      • ASTS Council 2015-2016
      • AST Board of Directors 2015-2016
    • 2015 Resources
      • 2015 Welcome Letter
      • ATC 2015 Program Planning Committees
      • ASTS Council 2014-2015
      • AST Board of Directors 2014-2015
      • 2015 Conference Schedule
  • Search

Usefulness of the Assessment of CT-Based Donor Kidney Function Compared with Radionuclide Scintigraphy

K. Park, J. Yoon, H. Kim, C. Baek, S. Park, H. Kim

Division of Nephrology, Department of Internal Medicine, Asan Medical Center, SEOUL, Korea, Republic of

Meeting: 2019 American Transplant Congress

Abstract number: B150

Keywords: Glomerular filtration rate (GFR), Kidney transplantation, Radiologic assessment, Renal function

Session Information

Session Name: Poster Session B: Kidney Donor Selection / Management Issues

Session Type: Poster Session

Date: Sunday, June 2, 2019

Session Time: 6:00pm-7:00pm

 Presentation Time: 6:00pm-7:00pm

Location: Hall C & D

*Purpose: Pretransplant graft volume and function has been demonstrated to be an important factor in subsequent allograft outcomes. Most transplant centers underwent renal split function test to assess functional asymmetry with technetium dimercaptosuccinic acid (99mTc-DMSA) renography and or computed tomography (CT). We evaluated which of the two methods better reflected posttransplant renal function.

*Methods: We analyzed 159 living donors who underwent pretransplant kidney evaluation with both 99mTc-DMSA renography and CT, and their matching recipients. We measured glomerular filtration rate (GFR) in donor with 51Chromium (Cr) plasma clearance and in recipients using the chronic kidney disease epidemiology collaboration formula (CKD-EPI) equation at 1, 6, and 12 months after transplantation. Kidney volumes were calculated using semi-automatic, three-dimensional (3D) CT volumetry methods. Absolute transplanted graft GFR was calculated by donor GFR (ml/min) x the proportion of donated kidney to total kidney (transplanted kidney volume/total kidney volume in CT, and transplanted kidney isotope uptake/total uptake in renography).

*Results: The mean absolute transplanted graft GFR were 53.3±10.6 ml/min by renography and 53.5±10.7 ml/min by CT (p=0.872). Posttransplant graft functions were 84.5±18.6, 72.3±14.1, and 74.9±16.7 ml/min/1.73m2 at 1, 6, and 12 months after transplantation, respectively. Pearson correlation coefficients between absolute transplanted graft GFR and posttransplant GFR were 0.289, 0.362, and 0.256 in renography (all p<0.001), and 0.318, 0.378, and 0.269 (all p<0.001) in CT at 1, 6, and 12 months, respectively. Multiple linear regression analysis adjusted by age and gender demonstrated that a 1 ml/min increase in absolute transplanted graft GFR calculated by 3D CT volume was associated with 0.56±0.13 ml/min/1.73m2 increase in posttransplant GFR, and one year increase in recipient age was associated with a 0.46±0.12 ml/min/1.73m2 reduction of GFR.

*Conclusions: 3D CT volumetry method is more useful to predict renal graft outcome than isotope renography before transplantation.

  • Tweet
  • Click to email a link to a friend (Opens in new window) Email
  • Click to print (Opens in new window) Print

To cite this abstract in AMA style:

Park K, Yoon J, Kim H, Baek C, Park S, Kim H. Usefulness of the Assessment of CT-Based Donor Kidney Function Compared with Radionuclide Scintigraphy [abstract]. Am J Transplant. 2019; 19 (suppl 3). https://atcmeetingabstracts.com/abstract/usefulness-of-the-assessment-of-ct-based-donor-kidney-function-compared-with-radionuclide-scintigraphy/. Accessed June 1, 2025.

« Back to 2019 American Transplant Congress

Visit Our Partner Sites

American Transplant Congress (ATC)

Visit the official site for the American Transplant Congress »

American Journal of Transplantation

The official publication for the American Society of Transplantation (AST) and the American Society of Transplant Surgeons (ASTS) »

American Society of Transplantation (AST)

An organization of more than 3000 professionals dedicated to advancing the field of transplantation. »

American Society of Transplant Surgeons (ASTS)

The society represents approximately 1,800 professionals dedicated to excellence in transplantation surgery. »

Copyright © 2013-2025 by American Society of Transplantation and the American Society of Transplant Surgeons. All rights reserved.

Privacy Policy | Terms of Use | Cookie Preferences