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UNOS Regional Risk Factors for Graft Failure in Kidney Transplantation

E. Molmenti, A. Alex, L. Rosen, E. Sameyah, M. Bhaskaran, J. Nicastro, M. Sachdeva, K. Calderon, R. Morgan, E. Siskind, M. Mendez, R. Schwarz, S. Fishbane, A. Bellucci, G. Coppa

Surgery, Hofstra North Shore-LIJ School of Medicine, Manhasset, NY
Research, Hofstra North Shore-LIJ School of Medicine, Manhasset, NY
Medicine, Hofstra North Shore-LIJ School of Medicine, Manhasset, NY
Administration, Hofstra North Shore-LIJ School of Medicine, New Hyde Park, NY

Meeting: 2013 American Transplant Congress

Abstract number: A768

Aim: To identify UNOS regional variations in graft failure.

Methods: UNOS database of 17,273 adult recipients transplanted from 06-30-2004 to 01-01-2007. Potential risk factors of interest included UNOS transplant region (region 1 – region 11). Factors significantly associated with graft failure at the level of P < 0.10 were included in the multivariate model. Cause-specific Cox (proportional hazards) regression was used to model time until graft failure as a function of transplant region. Age was not of direct interest, but was included in the model as a potential confounder. For purposes of cause-specific analysis, patients who died without experiencing a previous graft failure were considered to be censored along with patients who neither experienced a graft failure nor death.

Results: Table 1

Conclusions: UNOS regional variations in outcome should be further studied and evaluated.

Region   <0.0001
Region 1 1.38 (1.08, 1.77)  
Region 2 1.93 (1.64, 2.27)  
Region 3 1.32 (1.11, 1.57)  
Region 4 1.51 (1.26, 1.83)  
Region 5 Reference  
Region 6 1.16 (0.87, 1.55)  
Region 7 1.50 (1.26, 1.78)  
Region 8 1.19 (0.96, 1.48)  
Region 9 1.61 (1.32, 1.96)  
Region 10 1.31 (1.08, 1.59)  
Region 11 1.48 (1.23, 1.77)  
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To cite this abstract in AMA style:

Molmenti E, Alex A, Rosen L, Sameyah E, Bhaskaran M, Nicastro J, Sachdeva M, Calderon K, Morgan R, Siskind E, Mendez M, Schwarz R, Fishbane S, Bellucci A, Coppa G. UNOS Regional Risk Factors for Graft Failure in Kidney Transplantation [abstract]. Am J Transplant. 2013; 13 (suppl 5). https://atcmeetingabstracts.com/abstract/unos-regional-risk-factors-for-graft-failure-in-kidney-transplantation/. Accessed May 17, 2025.

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