The Effect of Transplant Center Volume on Survival Outcomes for Patients Listed for Simultaneous Liver and Kidney Transplantation.
1Internal Medicine, The Ohio State University Wexner Medical Center, Columbus, OH
2Anesthesiology and Pain Medicine, Nationwide Children's Hospital, Columbus, OH
3General Surgery, The Ohio State University Wexner Medical Center, Columbus, OH
4Comprehensive Transplant Center, The Ohio State University Wexner Medical Center, Columbus, OH
5Pulmonary Medicine, Nationwide Children's Hospital, Columbus, OH
6Gastroenterology, Hepatology, and Nutrition, The Ohio State University Wexner Medical Center, Columbus, OH
Meeting: 2017 American Transplant Congress
Abstract number: D186
Keywords: Allocation, Kidney/liver transplantation, Outcome
Session Information
Session Name: Poster Session D: Liver - Kidney Issues in Liver Transplantation
Session Type: Poster Session
Date: Tuesday, May 2, 2017
Session Time: 6:00pm-7:00pm
Presentation Time: 6:00pm-7:00pm
Location: Hall D1
This study examines the effect of center volume on survival differences between Simultaneous Liver Kidney Transplantation (SLKT) and liver transplantation alone (LTA).
Methods: The United Network of Organ Sharing database was queried for adult patients listed for SLKT between February 2002 and December 2015. Survival differences for LTA vs. SLKT were evaluated using stratified Cox regression with interaction between transplant type and center volume.
Results: Over the study period 393 of 4580 patients (9%) listed for SLKT underwent a LTA. Overall mortality was more common among LTA recipients (180/393, 46%) than SLKT recipients (1,107/4,187, 26%). 
The Cox model predicted a significant survival disadvantage for receiving LTA vs. SLKT (Hazard Ratio, HR=2.84; 95% CI: 2.21, 3.66; p<0.001) in centers performing at least 30 SLKT over the study period. This disadvantage was attenuated at centers that performed an increased number of SLKT over the study period, with a 3% reduction (HR=0.97; 95% CI: 0.95, 0.99; p=0.010) for every 10 SLKs performed. 
Conclusion: Standardization of SLKT listing criteria may be pertinent for smaller centers with a larger survival disadvantage between SLKT and LTA populations.
CITATION INFORMATION: Modi R, Tumin D, Beal E, Hayes Jr. D, Hanje J, Michaels A, Washburn K, Conteh L, Black S, Mumtaz K. The Effect of Transplant Center Volume on Survival Outcomes for Patients Listed for Simultaneous Liver and Kidney Transplantation. Am J Transplant. 2017;17 (suppl 3).
To cite this abstract in AMA style:
Modi R, Tumin D, Beal E, Jr DHayes, Hanje J, Michaels A, Washburn K, Conteh L, Black S, Mumtaz K. The Effect of Transplant Center Volume on Survival Outcomes for Patients Listed for Simultaneous Liver and Kidney Transplantation. [abstract]. Am J Transplant. 2017; 17 (suppl 3). https://atcmeetingabstracts.com/abstract/the-effect-of-transplant-center-volume-on-survival-outcomes-for-patients-listed-for-simultaneous-liver-and-kidney-transplantation/. Accessed November 21, 2024.« Back to 2017 American Transplant Congress