Strategies to Promote Pediatric Kidney Transplant Program in China – A Coming Opportunity with Development of Pediatric Deceased Donation.
1Organ Transplant Center, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China
2China Organ Transplant Response System Research Center, Shenzhen, China
3Department of Pediatrics, Peking University First Hospital, Beijing, China
4Data Center of Chinese Scientic Registry of Kidney Transplantation, Beijing, China
Meeting: 2017 American Transplant Congress
Abstract number: D162
Keywords: Allocation, Donation, Kidney transplantation, Pediatric
Session Information
Session Name: Poster Session D: Kidney: Pediatric
Session Type: Poster Session
Date: Tuesday, May 2, 2017
Session Time: 6:00pm-7:00pm
Presentation Time: 6:00pm-7:00pm
Location: Hall D1
Introduction
This article demonstrates the opportunity and challenges of current pediatric kidney transplant program in China, based on the analysis study of the national registry data.
Materials and Methods
Registry data was collected from Chinese Scientific Registry of Kidney Transplantation (CSRKT) and China Organ Transplant Response System (COTRS).
Results and Discussion
1278 primary pediatric KTx was performed in 110 transplant units between 2010 to 2015. CDCD program apparently increased annual pediatric KTx number by 2.6 times. The 1- and 5-year graft survival rate was 93.8% and 84.1%. The graft of 73% of CDCD pediatric KTx was from pediatric donation. The 75% of total pediatric KTx was accomplished by 27% of transplant centers.
A total of 1009 KTx from pediatric deceased donation was performed in 74 transplant between 2010 and 2015. There was only 12.6% of pediatric donated kidneys were allocated to pediatric recipients.
The top 10 centers completed 63% of total KTx from pediatric donors. The graft loss rate of pediatric donated kidneys varied from 0% to 50% with a median of 1.4% among individual institutes.
Only 4.6% of ESRD children in hospitals received kidney transplantation in China. Two main obstacles hinder the progress: (1) Insufficient candidates on the waiting list. Many factors including poor income, lacking of insurance coverage, immature social welfare and weak humanitarian aid system drive ESRD children away from registration of waiting list. (2) Low priority for children in organ sharing. Most pediatric kidneys were locally allocated to adult recipients.
Conclusion
Pediatric deceased donation provides potential opportunities for growth of pediatric KTx program in China. Higher priority is demanded for pediatric candidates in allocation of pediatric donated kidneys. A broad cooperative network consisting of pediatric nephrologist, transplant surgeon, social welfare organization and participation of healthcare system will promote rapid progress of pediatric KTx program in China.
CITATION INFORMATION: Liu L, Wang H, Ding J, Shi B, Zhong X, Jiang W, Chen L, Zhang H, Wang C. Strategies to Promote Pediatric Kidney Transplant Program in China – A Coming Opportunity with Development of Pediatric Deceased Donation. Am J Transplant. 2017;17 (suppl 3).
To cite this abstract in AMA style:
Liu L, Wang H, Ding J, Shi B, Zhong X, Jiang W, Chen L, Zhang H, Wang C. Strategies to Promote Pediatric Kidney Transplant Program in China – A Coming Opportunity with Development of Pediatric Deceased Donation. [abstract]. Am J Transplant. 2017; 17 (suppl 3). https://atcmeetingabstracts.com/abstract/strategies-to-promote-pediatric-kidney-transplant-program-in-china-a-coming-opportunity-with-development-of-pediatric-deceased-donation/. Accessed May 13, 2025.« Back to 2017 American Transplant Congress