Background

Simultaneous cadaveric pancreas and living-donor kidney transplantation(SPLK) is an attractive approach for uremic Type I diabetic patients, due to its distinct advantages from living kidney donation and shorter waiting time for simultaneous deceased pancreas and kidney transplantation(SPK). However it needs to be defined whether the graft survival of SPLK is comparable to SPK.

Methods

Among the total 262 pancreas transplantation performed in Asan Medical Center, 29(11.1%) SPLK have been done between September 2009 and Sep 2014.

Result

The patients with SPLK were 14 males with a mean age of 37.5±6.5years. Median waiting time for pancreas transplantation 62 days [IQR 30-200] in SPLK compared with 1045 days [413-1430] in SPK.

Preemptive transplantation was performed in 10 (34.5%) patients. Sibling was most frequent kidney donor (n=13, 44.8%).

3 year pancreas, kidney graft and patient survival rates were 100%. During 910 days follow up, one pancreas rejection and 5 kidney rejection developed diagnosed by urine amylase and renal biopsy; all events were reversed by steroid pulse therapy.

ConclusionIn the case when living kidney donation is available, SPLK shortened the waiting time for pancreas transplantation and expanded the organ donor pool by the same pattern of pancreas transplantation alone in which donor pool for pancreas transplantation alone is not many in our country. As a single procedure, SPLK has obvious advantages like SPK or living donor kidney transplantation alone with comparable graft survival of both pancreas and kidney.

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