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Risk Factors for Failure to Complete Post-Donation Follow-Up among Obese Living Kidney Donors

R. Reed,1 P. MacLennan,1 B. Shelton,1 M. Mustian,1 D. McWilliams,1 D. Sawinski,2 J. Locke.1

1Surgery, University of Alabama at Birmingham, Birmingham, AL
2Medicine, University of Pennsylvania, Philadelphia, PA.

Meeting: 2018 American Transplant Congress

Abstract number: C152

Keywords: Multivariate analysis

Session Information

Session Name: Poster Session C: Kidney Living Donor Issues

Session Type: Poster Session

Date: Monday, June 4, 2018

Session Time: 6:00pm-7:00pm

 Presentation Time: 6:00pm-7:00pm

Location: Hall 4EF

Introduction: Living kidney donors in the United States who were obese at the time of donation are at greater risk of end-stage renal disease than their non-obese counterparts, and may benefit from more intensive post-donation follow-up. Compared to their non-obese counterparts, obese living donors are less likely to have complete follow-up data. It is unknown what factors may be driving greater risk for incomplete follow-up among obese living donors.

Methods: Adult living kidney donors with obesity (body mass index ≥ 30 kg/m2) at donation and reported to the Scientific Registry of Transplant Recipients from January 2005-July 2015 were included (n=13,831). Donor characteristics were compared based on having a recorded serum creatinine at 6-months post-donation, and multilevel logistic regression models were used to estimate odds of 6-month creatinine measurement, with a random intercept for recovery center.

Results: Obese donors who were older, female, Caucasian, married, had a history of hypertension, and were insured at donation were more likely to have a 6-month serum creatinine recorded on unadjusted analyses; obese donors with less than a college education or those biologically related to their recipient were less likely to have a 6-month serum creatinine. After adjustment, older age, female sex, and donation following the implementation of new center follow-up requirements were associated with higher odds of 6-month creatinine, while lower odds of 6-month creatinine were seen for biologically-related donors and donors at centers with higher total living donor volume.

Conclusion: Obese donors biologically related to their recipient or who donated at a high volume living donor center were less likely to have 6-month follow-up. These findings suggest the need for targeted education and intervention both at the patient and center level to increase follow-up among obese living donors.

CITATION INFORMATION: Reed R., MacLennan P., Shelton B., Mustian M., McWilliams D., Sawinski D., Locke J. Risk Factors for Failure to Complete Post-Donation Follow-Up among Obese Living Kidney Donors Am J Transplant. 2017;17 (suppl 3).

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To cite this abstract in AMA style:

Reed R, MacLennan P, Shelton B, Mustian M, McWilliams D, Sawinski D, Locke J. Risk Factors for Failure to Complete Post-Donation Follow-Up among Obese Living Kidney Donors [abstract]. https://atcmeetingabstracts.com/abstract/risk-factors-for-failure-to-complete-post-donation-follow-up-among-obese-living-kidney-donors/. Accessed June 6, 2025.

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