Renal Allograft Outcomes with Renal Artery Angioplasty and/or Stenting in Transplant Renal Artery Stenosis.

E. Tantisattamo,¹ A. Chokechanachaisakul,² S. Pitukweerakul,³ P. Ratanasrimetha,⁴ A. Shetty,² O. Traitanon,⁵ L. Gallon.²

¹Oakland University William Beaumont School of Medicine, Royal Oak, MI
²Northwestern University, Chicago, IL
³Presence St. Francis Hospital, Evanston, IL
⁴Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand
⁵Thammasart University Hospital, Pathumthani, Thailand.

Meeting: 2016 American Transplant Congress

Abstract number: B230

Keywords: Angiography, Hypertension, Renal artery stenosis, Renal dysfunction

Session Information

Session Name: Poster Session B: Kidney: Cardiovascular and Metabolic

Session Type: Poster Session

Date: Sunday, June 12, 2016

Session Time: 6:00pm-7:00pm

Presentation Time: 6:00pm-7:00pm

Location: Halls C&D

Background: The renal allograft function and blood pressure (BP) control after renal artery angioplasty±stenting for transplant renal artery stenosis (TRAS) is unclear. We aim to identify these outcomes after this procedure.

Methods: A computerized search of medical records from 2008 through 2015 yielded 1,905 kidney transplant recipients in whom angiography-proven TRAS was diagnosed in 19. Each 19 patients were individually matched to 2 subjects without TRAS based on age, gender, diabetes, and year of kidney transplantation.

Results: Mean age was 50.3+3.5 and 36.8% had diabetes. The onset of TRAS was 3.3+3.4 months. (range:0.4-63.2). The majority of patients were Caucasian (37%) and African American (32%) and 84% were male. At the time of angioplasty, SBP (157.3+4.6 vs. 138.3+ 3.7, p=0.003) and DBP (84.1+3.5 vs. 74.4+1.8, p=0.0074) were significantly higher in TRAS group while serum creatinine (SCr) did not differ. Mean SBP within 1 month after transplant renal artery angioplasty±stenting was significantly lower than pre-procedure SBP (137.9±6.7 vs. 157.3±4.6 mmHg, p=0.0186). However, mean DBP (77.4±2.9vs.84.1±3.5mmHg, p=0.0605) and SCr (1.7±0.2 and 2.4±0.6 mg/dL, p=0.6800) were not significantly different (Figure1). Mean duration of follow up after diagnosed TRAS was 2.1±0.4 years (range:0.02-6.3). There was no improvement in SBP, DBP, and SCr at the time of the most recent followed-up compared to those before angioplasty. Three-year renal allograft survivals were 94.7 and 92.1% in TRAS and non-TRAS groups, respectively. One patient (5%) had arterial dissection during the procedure.

Conclusions: Although decreasing BP in short-term, renal artery angioplasty±stenting may not improve BP and renal allograft function in the long-term follow-up with potential procedure-related complications.

CITATION INFORMATION: Tantisattamo E, Chokechanachaisakul A, Pitukweerakul S, Ratanasrimetha P, Shetty A, Traitanon O, Gallon L. Renal Allograft Outcomes with Renal Artery Angioplasty and/or Stenting in Transplant Renal Artery Stenosis. Am J Transplant. 2016;16 (suppl 3).

To cite this abstract in AMA style:

Tantisattamo E, Chokechanachaisakul A, Pitukweerakul S, Ratanasrimetha P, Shetty A, Traitanon O, Gallon L. Renal Allograft Outcomes with Renal Artery Angioplasty and/or Stenting in Transplant Renal Artery Stenosis. [abstract]. Am J Transplant. 2016; 16 (suppl 3). https://atcmeetingabstracts.com/abstract/renal-allograft-outcomes-with-renal-artery-angioplasty-andor-stenting-in-transplant-renal-artery-stenosis/. Accessed November 22, 2024.

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