Racial and Socioeconomic Influences on Kidney Transplantation. A 10 Year Retrospective Study
Recanati/Miller Transplantation Institute, The Mount Sinai Hospital, New York, NY.
Meeting: 2018 American Transplant Congress
Abstract number: A309
Keywords: African-American, Kidney transplantation, Outcome
Session Information
Session Name: Poster Session A: Non-Organ Specific: Disparities to Outcome and Access to Healthcare
Session Type: Poster Session
Date: Saturday, June 2, 2018
Session Time: 5:30pm-7:30pm
Presentation Time: 5:30pm-7:30pm
Location: Hall 4EF
Introduction: Racial disparities in kidney transplantation are a widely discussed topic. Studies have shown less access to listing and transplantation, and worse graft survival in African Americans compared to Caucasians.
In our institution, African Americans comprise the highest percentage of our listed and transplanted patients; 41% of our listed patients and 42% of our diseased donor recipients are African Americans. Nationally, these percentages are 33% and 25% respectively.
Methods: We studied 1333 African American and Caucasian patients who had kidney transplant in our institution from 1/1/2005-12/31/2014.The primary end points of our study were differences in graft survival, patient survival, cause of graft loss, and incidence of rejection. The secondary end points were differences in access to listing and transplantation.
Results: We found no difference between African Americans and Caucasians in patient survival. We found lower graft survival in African Americans, but when we adjusted for socioeconomic status there was no difference between the two groups. However, the incidence of rejection was higher among African Americans throughout all socioeconomic levels.
We found no difference in access to listing and transplantation.
Caucasians N=696 | African Americans N=637 | ||
Mean time to listing (days) | 85.35 | 93.84 | P=0.19 |
Median time from listing to transplant (days) | 1544.8 | 1725.42 | P=0.14 |
Patient survival
3 year 5 year 10 year |
90%
87% 68% |
91%
86% 69% |
P=0.2 |
Graft Survival (adjusted for socioeconomic status)
1 year 3 year 5 year 10 year |
94%
90.5% 82.3% 64% |
95.5%
85.5% 79.3% 63.2% |
P=0.655 |
Rejection | 3.8% | 8.6% | P=0.001 |
Discussion: Most studies show lower graft survival in African Americans vs Caucasians. In our institution we did not find such difference when we compared similar socioeconomic groups. However, we did find lower graft survival in patients with lower socioeconomic status irrespective of race.
CITATION INFORMATION: Arvelakis A., Lerner S., Wadhera V., Delaney V., Ames S., Shegal V., Kent R., DeBoccardo G., Singh N., Florman S., Shapiro R. Racial and Socioeconomic Influences on Kidney Transplantation. A 10 Year Retrospective Study Am J Transplant. 2017;17 (suppl 3).
To cite this abstract in AMA style:
Arvelakis A, Lerner S, Wadhera V, Delaney V, Ames S, Shegal V, Kent R, DeBoccardo G, Singh N, Florman S, Shapiro R. Racial and Socioeconomic Influences on Kidney Transplantation. A 10 Year Retrospective Study [abstract]. https://atcmeetingabstracts.com/abstract/racial-and-socioeconomic-influences-on-kidney-transplantation-a-10-year-retrospective-study/. Accessed November 21, 2024.« Back to 2018 American Transplant Congress