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Pulmonary Complications in Living Liver Donors

D. Esendagli1, E. Ayvazoglu Soy2, E. Kupeli1, A. Akdur2, S. Yildirim2, A. Torgay3, S. Boyacioglu4, M. Haberal2

1Pulmonary Diseases, Baskent University, Ankara, Turkey, 2Transplantation, Baskent University, Ankara, Turkey, 3Anesthesiology, Baskent University, Ankara, Turkey, 4Gastroenterology, Baskent University, Ankara, Turkey

Meeting: 2019 American Transplant Congress

Abstract number: B343

Keywords: Liver grafts

Session Information

Session Name: Poster Session B: Liver: Living Donors and Partial Grafts

Session Type: Poster Session

Date: Sunday, June 2, 2019

Session Time: 6:00pm-7:00pm

 Presentation Time: 6:00pm-7:00pm

Location: Hall C & D

*Purpose: Due to the shortage of deceased donors, living donor liver transplantation has been the main treatment option for the end – stage liver disease. The possible complications that might come out postoperatively may be one of the main drawbacks for donation. Many studies related to the pulmonary complications seen in solid organ transplantation have been focused in organ recipients rather than donors. This study aims to analyze the pulmonary complications encountered after liver donation.

*Methods: Since 1988, we performed 611 liver transplantations in our centers. This study was performed retrospectively by analyzing the data of the living liver donors who underwent surgery between January 2013 to October 2018 in Baskent University.

*Results: A total of 157 liver transplantations were performed in the specified timeline. 121 (77%) of the donors were living ones whereas 36 (23%) of them were deceased. The average age of donors was 36.3 ± 14.8 years. The living donors were all evaluated pre-operatively and only 5 (4%) of them had a diagnosed lung disease mainly asthma and COPD. 8 (6.6%) donors were found to have latent tuberculosis upon a positive Quantiferon test and isoniazide prophylaxis was recommended to the organ recipients post-operatively. 51.2 % of the living donors were either active or ex-smokers with an average of 14 package/year. Only 9 (7.4%) donors developed pulmonary complications in the post-operative period; 6 patients had plevral effusion, 4 patients had atelectasia, 2 patients developed pneumonia and 2 of them had a pulmonary embolism in the 2nd day after operation. The incidence of pulmonary complications in our center in living liver donors found to be lower than literature.

*Conclusions: In living donation; donor morbidity and mortality should be minimum. Ideal evaluation of donor candidates is essential to assess graft function for safety of both donor and recipient.

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To cite this abstract in AMA style:

Esendagli D, Soy EAyvazoglu, Kupeli E, Akdur A, Yildirim S, Torgay A, Boyacioglu S, Haberal M. Pulmonary Complications in Living Liver Donors [abstract]. Am J Transplant. 2019; 19 (suppl 3). https://atcmeetingabstracts.com/abstract/pulmonary-complications-in-living-liver-donors/. Accessed May 12, 2025.

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