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Potential Living Kidney Donors’ Interest in Kidney Paired and Non-Directed Donation

D. R. Helfer1, A. D. Love1, J. M. Konel1, J. Stanton2, M. G. Bowring1, K. Kumar1, S. R. Weeks1, M. L. Henderson1, D. L. Segev1, A. M. Cameron1, J. M. Garonzik Wang1

1Johns Hopkins University, Baltimore, MD, 2East Carolina University, Greenville, NC

Meeting: 2019 American Transplant Congress

Abstract number: 128

Keywords: Donation, Kidney transplantation, Renal failure

Session Information

Session Name: Concurrent Session: Kidney Living Donor: Quality and Selection

Session Type: Concurrent Session

Date: Sunday, June 2, 2019

Session Time: 4:30pm-6:00pm

 Presentation Time: 5:18pm-5:30pm

Location: Ballroom A

*Purpose: Kidney Paired (KPD) and Non-Directed Donation (NDD) are avenues to increase living donation and address organ shortage. We investigated interest in KPD and NDD among potential living donors (PLDs).

*Methods: We retrospectively identified 712 PLDs who completed the Kidney Donor Questionnaire (KDQ) and initiated donor evaluation at our center between 3/2016-6/2018. Responses to questions related to KPD and NDD were used to determine PLD interest. Multivariable logistic regression was used to quantify the association between PLD characteristics and interest in KPD and NDD.

*Results: Among surveyed PLDs, 73% were interested in KPD (Table 1A). These individuals were more likely to be unrelated to the recipient, have no family history of kidney disease, and able to take time-off post-donation (Table 1A). Conversely, 34% of PLDs were interested in NDD (Table 1B). PLDs interested in NDD were more likely to be White or Caucasian, unrelated to the recipient, have no family history of kidney disease, and able to take time-off post-donation (p<0.05, Table 1B). After adjusting for PLD characteristics, PLDs who felt pressured to donate had lower odds of being interested in either KPD (aOR: 0.160.380.92, Table 2A) or NDD (aOR: 0.050.221.00, Table 2B).

*Conclusions: Prior to evaluation, the majority of PLDs were interested in KPD, but not NDD. Additionally, racial/ethnic background, relationship to the recipient, ability to receive time-off, and perceived pressure to donate were factors influencing their interest.

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To cite this abstract in AMA style:

Helfer DR, Love AD, Konel JM, Stanton J, Bowring MG, Kumar K, Weeks SR, Henderson ML, Segev DL, Cameron AM, Wang JMGaronzik. Potential Living Kidney Donors’ Interest in Kidney Paired and Non-Directed Donation [abstract]. Am J Transplant. 2019; 19 (suppl 3). https://atcmeetingabstracts.com/abstract/potential-living-kidney-donors-interest-in-kidney-paired-and-non-directed-donation/. Accessed May 17, 2025.

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