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Pancreas Transplants in Asian Recipients

A. Gruessner, C. Gruessner, S. Saggi, J. Renz

SUNY Downstate Medical Center, Brooklyn, NY

Meeting: 2020 American Transplant Congress

Abstract number: D-249

Keywords: Outcome, Pancreas transplantation

Session Information

Session Name: Poster Session D: Pancreas and Islet: All Topics

Session Type: Poster Session

Date: Saturday, May 30, 2020

Session Time: 3:15pm-4:00pm

 Presentation Time: 3:30pm-4:00pm

Location: Virtual

*Purpose: Over the years, a change in patients receiving a pancreas transplant could be observed. While in the beginning the standard pancreas transplant recipient was white with type 1 diabetes mellitus, over the year the number of transplants in minorities increase. The purpose of this study was to describe Asian recipients and compare the outcomes of these transplants to outcomes in African American recipients.

*Methods: Between 1994 and 2018 a total of 304 primary adult pancreas transplants were reported to UNOS/IPTR in the US. Most of the transplants were SPKs (n=281 (92%)). Therefore, this study will concentrate on SPKs transplant. At the same time period, 3,729 primary pancreas transplants were performed in African American recipients were also the majority were SPKs (91%). Comprehensive uni-and multivariate analyses were performed to describe patient and graft survival in the Asian population.

*Results: Table 1 shows the basic characteristics of the 2 minority groups. The majority of Asian SPK recipients reported type 1 diabetes mellitus as reason for the transplant (70%) but with 30% is the rate of patients with type 2 diabetes twice as high compared to African American recipients. Asian recipients are slightly older which is the impact of the higher rate of type 2 diabetes mellitus, but the rate of obese recipients is just one third of the rate in AfricanAmericans. More Asian women received a transplant but age at transplant was comparable.

Overall patient and graft survival was excellent in both groups and no differences could be detected (p=0.79). One year patient survival reached both 97% in both groups (p=0.8). One year pancreas and also kidney graft survival were with 89% and 96% excellent. The diabetes type also had no impact on patient or graft survival in the 2 groups. The multivariate analysis confirmed that there was no difference in outcome between Asian and AfricanAmerican pancreas transplant recipient. In both groups was female gender, young age long preservation time old donor age a significant risk factor for graft survival.

*Conclusions: This study showed that pancreas transplantation can also be considered for Asian recipient with excellent outcome in patient and graft survival. This is especially an option for the slim Asians with type 2 diabetes mellitus.

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To cite this abstract in AMA style:

Gruessner A, Gruessner C, Saggi S, Renz J. Pancreas Transplants in Asian Recipients [abstract]. Am J Transplant. 2020; 20 (suppl 3). https://atcmeetingabstracts.com/abstract/pancreas-transplants-in-asian-recipients/. Accessed May 10, 2025.

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