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Pancreas Organ Underutilization: 15-Year Analysis.

S. Siddiqi, J. Almario, K. Villaroel-Gomez, J. Yoo, C. Blackburn, R. Batra, D. DiSabato, A. Lu, S. Akkina, A. Desai, R. Garcia-Roca.

Department of Surgery, Loyola University Medical Center, Maywood, IL

Meeting: 2017 American Transplant Congress

Abstract number: C208

Keywords: Allocation, Donation, Pancreas transplantation

Session Information

Session Name: Poster Session C: Pancreas and Islet (Auto and Allo) Transplantation

Session Type: Poster Session

Date: Monday, May 1, 2017

Session Time: 6:00pm-7:00pm

 Presentation Time: 6:00pm-7:00pm

Location: Hall D1

Pancreas recovery has declined by 32% over 15yrs. We analyzed national pancreas utilization rates for donors with suitable criteria for pancreas retrieval to understand this trend

METHODS

Using UNOS database from 2000-14, we identified 31,960 potential suitable pancreas donors. Exclusion criteria: age>40, BMI>30kg/m2, diabetes or alcohol history, positive serologies, liver/pancreas enzymes>500 and KDPI>85%. We compared pancreas utilization in 3 periods of 5yrs

RESULTS

Transplant rates have declined from 45.8 to 37.2% over time. Discard reasons that increased statistically include: donor quality(24.4 to 28.6%), unavailable recipients(9.1 to 12.6%) and DCD(2.5 to 5.5%). Other reasons remained similar: organ anatomy, no consent, CIT, shared vasculature, operational and CDT. Donor variables were statistically similar in the 3 periods

2000-04 2005-09 2010-14
N 10010 10853 10097
SEX(F%) 68 69 69
COD(%)
Anoxia 13.5 19.5 29
Trauma 67.8 63.8 55.6
CVA 15.5 13.3 11.9
Other 3.1 3.5 3.4
BMI 22.5±4 22.8±4 22.9±4
WIT 17.8±13 12.5±13 19.1±12
CDT 18.1±15 21.2±18 21.5±19
AMYLASE 137±235 140±265 118±192
CREATININE 1.1±1.1 1.2±1.1 1.2±1.3

DISCUSSION

“Donor quality” for refusal code has significantly increased despite acceptable pancreas donation parameters. Possibly, some relevant information in “donor highlight” and “medical history” comments in donornet may not be captured in other discrete fields, including HbA1C. Calculated travel time may be a significant reason to refuse organs after retrieval. Kidney sharing for thoracic and abdominal teams may limit organs to PTA recipients making allocation difficult

CONCLUSION

Declining pancreas transplant rates may be due DCD refusal, donor quality and increased difficulty in organ allocation. Improvement in donornet documentation with discrete fields may help understand organ underutilization.

CITATION INFORMATION: Siddiqi S, Almario J, Villaroel-Gomez K, Yoo J, Blackburn C, Batra R, DiSabato D, Lu A, Akkina S, Desai A, Garcia-Roca R. Pancreas Organ Underutilization: 15-Year Analysis. Am J Transplant. 2017;17 (suppl 3).

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To cite this abstract in AMA style:

Siddiqi S, Almario J, Villaroel-Gomez K, Yoo J, Blackburn C, Batra R, DiSabato D, Lu A, Akkina S, Desai A, Garcia-Roca R. Pancreas Organ Underutilization: 15-Year Analysis. [abstract]. Am J Transplant. 2017; 17 (suppl 3). https://atcmeetingabstracts.com/abstract/pancreas-organ-underutilization-15-year-analysis/. Accessed May 13, 2025.

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