ATC Abstracts

American Transplant Congress abstracts

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  • 2022 American Transplant Congress

    Humoral Response After a Third Dose of Sars-CoV-2 mRNA Vaccine in Transplant Recipients

    A. E. Woolley, N. Sharma, G. Zhou, A. Kim, E. Ryan, M. Joyce, H. Goldberg, M. Givertz, M. Mehra, E. Woodcome, V. Durney, S. Marshall, K. Townsend, A. Coppolino, S. Tullius, S. Malek, H. Mallidi, L. Baden, A. Chandraker

    Brigham & Women's Hospital, Boston, MA

    *Purpose: Prior studies demonstrated an increased immune response post-3rd COVID-19 vaccine dose when given 1-month post-2nd dose in solid organ transplant recipients (SOT). This study…
  • 2022 American Transplant Congress

    Changes in Cold Ischemia Time and Transplantation Practices with the Concentric Model of Kidney Allocation

    C. M. Puttarajappa1, P. Sood1, A. Tevar1, V. Gunabushanam1, S. Hariharan1, S. Mohan2

    1University of Pittsburgh Medical Center, Pittsburgh, PA, 2Columbia University, New York, NY

    *Purpose: Evaluate impact of the new concentric kidney allocation system (KAS250) on kidney utilization, allocation practices and cold ischemia time (CIT).*Methods: Using data from the…
  • 2022 American Transplant Congress

    Organs from Donors with Positive SARS-CoV-2 NAT+ Testing: A Report from the Ad Hoc Disease Transmission Advisory Committee

    L. Danziger-Isakov1, J. D. Goldman1, A. Wooley1, S. Pouch1, A. Agarwal1, G. Berry1, K. Dunn1, S. Ho1, M. Kittleson1, D. H. Lee1, D. Levine1, C. Marboe1, G. Marklin1, R. Razonable1, S. Taimur1, H. Te1, C. Fox2, C. Jett2, S. Booker2, D. Klassen2, R. LaHoz1

    1OPTN, Richmond, VA, 2UNOS, Richmond, VA

    *Purpose: Decision to transplant organs from SARS-CoV-2 NAT+ donors(N+D) balances risk of donor-derived infection with the scarcity of available organs to meet the needs of…
  • 2022 American Transplant Congress

    Barriers and Facilitators to Care for Patients with Failed Kidney Transplants

    A. Huml1, K. Berg2, A. Perzynski2, C. Sullivan2, A. Sehgal2

    1Department of Kidney Medicine, Cleveland Clinic, Cleveland, OH, 2Population Health Research Institute, The MetroHealth System, Cleveland, OH

    *Purpose: To understand the barriers and facilitators to care for patients with failed kidney transplants from the perspective of providers.*Methods: Qualitative study employed focus groups…
  • 2022 American Transplant Congress

    Rapid Formalin-Fixed Deceased Donor Kidney Biopsy Protocol – A Proof Of Concept

    M. R. Marvin1, G. Chen2, A. Kotru1, C. Koo1, P. Sanghi3, M. Moritz4, J. Clarke4, R. Hasz4

    1Transplant, Geisinger Medical Center, Danville, PA, 2Pathology, Geisinger Medical Center, Danville, PA, 3Transplant Nephrology, Geisinger Medical Center, Danville, PA, 4Gift of Life Donor Program, Philadelphia, PA

    *Purpose: Reducing kidney discard is a major priority for the transplant community. While frozen section biopsies are the current standard, they are fraught with technical…
  • 2022 American Transplant Congress

    “ABO-Adjusted CPRA”: A Unified Metric for Immunologic Compatibility in Kidney Transplantation

    L. Gragert1, M. Kadatz2, J. Alcorn3, D. Stewart3, D. Chang2, J. Gill2, R. Liwski4, H. Gebel5, E. Kransdorf6, J. Gill2, J. Lan2

    1Tulane University, New Orleans, LA, 2University of British Columbia, Vancouver, BC, Canada, 3UNOS, Richmond, VA, 4Dalhousie University, Halifax, NS, Canada, 5Emory University, Atlanta, GA, 6Cedars-Sinai, Beverly Hills, CA

    *Purpose: Implementation of the kidney allocation system in 2014 greatly reduced access disparity due to HLA sensitization. To address persistent disparities among both candidate cPRA…
  • 2022 American Transplant Congress

    Incidence of Delayed Graft Function in Kidneys Recovered After Normothermic Regional Perfusion

    L. James1, M. D'Angelo1, J. Carillo1, J. C. Berger1, D. E. Smith1, N. Moazami1, B. Lonze2

    1NYU Langone Health, New York, NY, 2NYU Langone Transplant Institute, New York, NY

    *Purpose: The use of normothermic reperfusion (NRP) following donation after circulatory death (DCD) is an emerging strategy for organ procurement. NRP technique reestablishes circulatory blood…
  • 2022 American Transplant Congress

    Patient Preferences for Waiting Time and Kidney Quality: A Discrete Choice Experiment

    S. Mehrotra

    Industrial Engineering and Management Sciences, Northwestern University, Evanston, IL

    *Purpose: The purpose of this study was to elicit patient preferences involving tradeoffs between a lower quality kidney offered today and a higher quality, future…
  • 2022 American Transplant Congress

    Implications of Accumulated Cold Time for US Kidney Transplantation Offer Acceptance

    M. Barah1, V. Kilambi2, J. Friedewald1, S. Mehrotra1

    1Industrial Engineering and Management Sciences, Northwestern University, Evanston, IL, 2Department of Engineering and Applied Sciences, RAND Corporation, Arlington, VA

    *Purpose: Reducing discard is a current focus in US transplantation of deceased donor kidneys. One cause for the discards is the avoidance of protracted cold…
  • 2022 American Transplant Congress

    Site-Directed Mutagenesis as a Tool to Investigate Immunogenicity of HLA Epitopes for Humoral Alloreactivity

    C. H. Maguire1, P. Crivello2, A. Tambur1

    1Northwestern University, Chicago, IL, 2University Hospital Essen, Essen, Germany

    *Purpose: Molecular mismatch load (MML) analysis has been a proposed approach to assess donor/recipient compatibility in support of organ allocation algorithms. While conceptually appealing, MML…
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