Abstracts Archive - Page 98 of 1683 - ATC Abstracts

2022 American Transplant Congress
Rapid Formalin-Fixed Deceased Donor Kidney Biopsy Protocol – A Proof Of Concept
M. R. Marvin¹, G. Chen², A. Kotru¹, C. Koo¹, P. Sanghi³, M. Moritz⁴, J. Clarke⁴, R. Hasz⁴
¹Transplant, Geisinger Medical Center, Danville, PA, ²Pathology, Geisinger Medical Center, Danville, PA, ³Transplant Nephrology, Geisinger Medical Center, Danville, PA, ⁴Gift of Life Donor Program, Philadelphia, PA
*Purpose: Reducing kidney discard is a major priority for the transplant community. While frozen section biopsies are the current standard, they are fraught with technical…
2022 American Transplant Congress
“ABO-Adjusted CPRA”: A Unified Metric for Immunologic Compatibility in Kidney Transplantation
L. Gragert¹, M. Kadatz², J. Alcorn³, D. Stewart³, D. Chang², J. Gill², R. Liwski⁴, H. Gebel⁵, E. Kransdorf⁶, J. Gill², J. Lan²
¹Tulane University, New Orleans, LA, ²University of British Columbia, Vancouver, BC, Canada, ³UNOS, Richmond, VA, ⁴Dalhousie University, Halifax, NS, Canada, ⁵Emory University, Atlanta, GA, ⁶Cedars-Sinai, Beverly Hills, CA
*Purpose: Implementation of the kidney allocation system in 2014 greatly reduced access disparity due to HLA sensitization. To address persistent disparities among both candidate cPRA…
2022 American Transplant Congress
Incidence of Delayed Graft Function in Kidneys Recovered After Normothermic Regional Perfusion
L. James¹, M. D'Angelo¹, J. Carillo¹, J. C. Berger¹, D. E. Smith¹, N. Moazami¹, B. Lonze²
¹NYU Langone Health, New York, NY, ²NYU Langone Transplant Institute, New York, NY
*Purpose: The use of normothermic reperfusion (NRP) following donation after circulatory death (DCD) is an emerging strategy for organ procurement. NRP technique reestablishes circulatory blood…
2022 American Transplant Congress
Patient Preferences for Waiting Time and Kidney Quality: A Discrete Choice Experiment
S. Mehrotra
Industrial Engineering and Management Sciences, Northwestern University, Evanston, IL
*Purpose: The purpose of this study was to elicit patient preferences involving tradeoffs between a lower quality kidney offered today and a higher quality, future…
2022 American Transplant Congress
Implications of Accumulated Cold Time for US Kidney Transplantation Offer Acceptance
M. Barah¹, V. Kilambi², J. Friedewald¹, S. Mehrotra¹
¹Industrial Engineering and Management Sciences, Northwestern University, Evanston, IL, ²Department of Engineering and Applied Sciences, RAND Corporation, Arlington, VA
*Purpose: Reducing discard is a current focus in US transplantation of deceased donor kidneys. One cause for the discards is the avoidance of protracted cold…
2022 American Transplant Congress
Site-Directed Mutagenesis as a Tool to Investigate Immunogenicity of HLA Epitopes for Humoral Alloreactivity
C. H. Maguire¹, P. Crivello², A. Tambur¹
¹Northwestern University, Chicago, IL, ²University Hospital Essen, Essen, Germany
*Purpose: Molecular mismatch load (MML) analysis has been a proposed approach to assess donor/recipient compatibility in support of organ allocation algorithms. While conceptually appealing, MML…
2022 American Transplant Congress
A Large-Scale National Cohort Study Assessing the Impact of Diabetes and Obesity on Kidney Transplant Outcomes
V. Rohan¹, M. Casey¹, S. Zemin², P. Baliga², D. Taber²
¹Surgery, Medical University of South Carolina, Charleston, SC, ²Medical University of South Carolina, Charleston, SC
*Purpose: Type 2 Diabetes Mellitus (T2DM) is the most common cause of renal failure in patients undergoing kidney transplantation (KT) and highly correlated with obesity.…
2022 American Transplant Congress
Biopsy Characteristics of Kidneys from a Single Large OPO
S. Bunnapradist¹, T. Seto², A. Cohen², T. Rosenthal¹, G. Danovitch¹
¹David Geffen School of Medicine, Los Angeles, CA, ²One Legacy, Los Angeles, CA
*Purpose: As deceased donor pool have expanded, kidney biopsy has been increasingly used to help determine organ suitability for transplant. There are concerns that biopsy…
2022 American Transplant Congress
Outcome of Pre-Emptive Kidney Transplantation in Children Under 6 Years of Age; A Single Center Experience in Japan
Y. Aoki¹, Y. Hamasaki¹, J. Hashimoto¹, A. Zaitsu², M. Kubota¹, M. Muramatsu¹, T. Kawamura¹, S. Shishido², K. Sakai¹
¹Nephrology, Toho University Faculty of Medicine, Tokyo, Japan, ²Pediatric Nephrology, Toho University Faculty of Medicine, Tokyo, Japan
*Purpose: Kidney transplantation (KT) is the preferred treatment for pediatric end stage renal disease, and pre-emptive kidney transplantation (PEKT) may reduce morbidity and mortality. KT…
2022 American Transplant Congress
Pericardial Effusion: A Potential Late Complication of COVID-19 Infection
O. Sogbein, A. Rizvi, M. Mujtaba, S. Hussain
Internal Medicine, Division of Nephrology, University of Texas Medical Branch, Galveston, TX
*Purpose: COVID-19 infection involves entry of SARS-CoV-2 virus into cells via interaction between its spike protein and angiotensin converting enzyme resulting in an NF-κβ mediated…