ATC Abstracts

American Transplant Congress abstracts

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  • 2022 American Transplant Congress

    Development and Validation of a Kidney Transplant-Specific Measure of Treatment Burden

    E. Lorenz1, T. Petterson1, I. Zaniletti1, K. Lackore1, B. Johnson1, M. Mai2, S. Nair3, A. Bentall1, K. Yost1, D. Eton1

    1Mayo Clinic, Rochester, MN, 2Mayo Clinic, Jacksonville, FL, 3Mayo Clinic, Scottsdale, AZ

    *Purpose: Treatment burden refers to the work involved in managing one’s health and its impact on well-being. Treatment burden has been associated with nonadherence and…
  • 2022 American Transplant Congress

    EBV+ PTLD Tumor MicroRNAs Detected in Circulating Extracellular Vesicles Are Decreased in Pediatric Transplant Recipients with EBV+ PTLD

    A. Sen1, J. Enriquez1, M. Rao1, M. Glass1, Y. Balachandran1, S. Syed1, C. Twist1, K. Weinberg1, S. D. Boyd1, D. Bernstein1, A. Trickey1, D. Gratzinger1, B. Tan1, M. G. Lapasaran1, M. A. Robien2, M. Brown3, B. Armstrong4, M. Sever4, D. Desai5, G. Mazariegos6, C. Chin7, T. Fishbein8, R. S. Venick9, A. Tekin10, H. Zimmermann11, R. U. Trappe12, C. O. Esquivel1, O. M. Martinez1, S. M. Krams1

    1Stanford U, Palo Alto, CA, 2NIH, Bethesda, MD, 3NIAID, Bethesda, MD, 4Rho, Durham, NC, 5UT Southwestern, Dallas, TX, 6Pittsburgh U, Pittsburgh, PA, 7CCHMC, Cincinnati, OH, 8Georgetown U, Washington, DC, 9UCLA, LA, CA, 10Miami U, Miami, FL, 11DIAKO Ev. Diakonie-Krankenhaus, Bremen, Germany, 12Charité - Universitätsmedizin, Berlin, Germany

    *Purpose: Post-transplant lymphoproliferative disorder (PTLD) is a serious complication of solid organ transplantation. Predisposing factors for PTLD include primary Epstein-Barr virus (EBV) infection in children,…
  • 2022 American Transplant Congress

    Disparities in Liver Transplantation in Patients with HCC Diagnosis

    C. Warren1, A. Zarrinpar2

    1Surgery, University of Florida Shands Health, Gainesville, FL, 2Surgery, University of Florida Health Shands, Gainesville, FL

    *Purpose: Disparities in outcomes of hepatocellular carcinoma (HCC) have not been adequately studied, especially in the context of liver transplantation (LT). We sought to identify…
  • 2022 American Transplant Congress

    Outcomes of Sodium-Glucose Cotransporter 2 Inhibitors and Glucagon-Like Peptide-1 Receptor Agonists in Diabetic Kidney Transplant Recipients

    T. S. Mahmoud1, J. Yagan1, A. Hasan2, O. Gheith1, M. Mostafa1, S. Rida1, N. El-Serwy1, M. Shaker1, M. Khalid1, P. Nair1, T. Alotaibi1

    1Nephrology, Organ Transplant Center, Kuwait, Kuwait, 2Immunometabolism, Dasman Diabetes Center, Kuwait, Kuwait

    *Purpose: The impact of the new glucose lowering therapies, sodium-glucose cotransporter 2 inhibitors (SGLT2i) and Glucagon-like peptide-1 receptor agonists (GLP-1RA), on managing patients with type…
  • 2022 American Transplant Congress

    Early Clinical Experience With Alvr109, A Partially Hla-matched Sars-cov-2 Specific T-cell Therapy, In Immunocompromised Patients With Covid-19

    G. Haidar1, J. Jacobs2, K. Hughes2, K. McCormick2, A. Naqvi2, M. Agha2, T. Bogdanovich2, B. Johnson2, J. Kozar2, E. Lendermon2, C. Marino2, A. Raptis2, F. Silveira2, W. Marshall3, M. Miller3, E. Atillasoy3, J. Mellors2

    1University of Pittsburgh, Pittsburgh, PA, 2UPitt, Pittsburgh, PA, 3Allovir, Waltham, MA

    *Purpose: Therapies for COVID-19 in immunocompromised (IC) patients (pts), including transplant (tx) pts, are limited. We describe our experience with ALVR109, an allogeneic, partially HLA-matched…
  • 2022 American Transplant Congress

    Differences in Strength and Longevity of SARS-CoV-2-Specific Adaptive Immunity Between Convalescent and Vaccinated SOT Patients and Immunocompetent Individuals

    L. Donadeu1, S. Gomez1, A. Fava'2, E. Crespo1, F. Moreso3, M. Lopez3, L. Lladó4, J. González4, I. Campos3, M. Muñoz3, J. Quintero3, J. Esperalba3, O. Bestard3

    1Vall d’Hebron Institut de Recerca (VHIR), Barcelona, Spain, 2Bellvitge University Hospital, L'Hospitalet de Llobregat. Barcelona, Spain, 3Vall d’Hebron University Hospital (HUVH), Barcelona, Spain, 4Bellvitge University Hospital, L'Hospitalet de Llobregat, Spain

    *Purpose: Short-term adaptive immune memory has been reported among immunocompetent (IC) and convalescent Solid Organ Transplant (SOT) individuals following SARS-CoV-2 infection as well as after…
  • 2022 American Transplant Congress

    Outcomes of Living Liver Donors Are Worse Than Those of Matched Healthy Controls: Nationwide Cohort Study

    J. Kim1, J. Choi2, J. Kim3, H. Kim4, J. Joh1

    1Department of Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea, Republic of, 2Department of Surgery, Myongji Hospital, Goyang, Korea, Republic of, 3Department of Urology, Soonchunhyang University Hospital, Soonchunhyang University College of Medicine, Seoul, Korea, Republic of, 4Department of Preventive Medicine, Korea University, Seoul, Korea, Republic of

    *Purpose: Donor death is the most serious complication of living liver donation, but is reported rarely. We investigated the actual mortality of living liver donors…
  • 2022 American Transplant Congress

    Epidemiology of Post Transplant Diabetes Mellitus

    S. Al Rasbi, I. Salmi

    Renal Medicine Department, The Royal Hospital, Bausher, Oman

    *Purpose: Diabetes mellitus (DM) is a common non-communicable disease and have serious metabolic complications that contribute to death, major cardiovascular events, organs failure, and increased…
  • 2022 American Transplant Congress

    Case Times For Brain Dead Donors: Longer Is Not Better, No Impact Of Longer Case Time On Organ Yield Or OPO Performance Tier

    M. J. Moritz1, R. Hasz1, H. Nathan1, E. Hunt2, S. Noreen3, A. Toll4

    1Gift of Life Donor Program, Philadelphia, PA, 2Surgery, Lehigh Valley Health Network, Allentown, PA, 3United Network for Organ Sharing, Richmond, VA, 4Research, United Network for Organ Sharing, Silverdale, WA

    *Purpose: Having observed the steady increase in case times, we wished to examine if this has impacted organ yield*Methods: We conducted a retrospective cohort study…
  • 2022 American Transplant Congress

    The Impact Of Monoclonal Antibody Against Sars-CoV2 And Vaccination On Outcomes In Kidney Transplant Recipients With Covid-19

    N. M. Ali, V. Tatapudi, R. Chand, k. Sureau, S. Mehta, R. Montgomery

    NYU Langone Transplant Institute, New York, NY

    *Purpose: Solid organ transplant recipients are at high risk of morbidity and mortality from coronavirus disease 2019 (COVID-19) with mortality rates as high as 30%…
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