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American Transplant Congress abstracts

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  • 2022 American Transplant Congress

    Incidence of Delayed Graft Function in Kidneys Recovered After Normothermic Regional Perfusion

    L. James1, M. D'Angelo1, J. Carillo1, J. C. Berger1, D. E. Smith1, N. Moazami1, B. Lonze2

    1NYU Langone Health, New York, NY, 2NYU Langone Transplant Institute, New York, NY

    *Purpose: The use of normothermic reperfusion (NRP) following donation after circulatory death (DCD) is an emerging strategy for organ procurement. NRP technique reestablishes circulatory blood…
  • 2022 American Transplant Congress

    Patient Preferences for Waiting Time and Kidney Quality: A Discrete Choice Experiment

    S. Mehrotra

    Industrial Engineering and Management Sciences, Northwestern University, Evanston, IL

    *Purpose: The purpose of this study was to elicit patient preferences involving tradeoffs between a lower quality kidney offered today and a higher quality, future…
  • 2022 American Transplant Congress

    Implications of Accumulated Cold Time for US Kidney Transplantation Offer Acceptance

    M. Barah1, V. Kilambi2, J. Friedewald1, S. Mehrotra1

    1Industrial Engineering and Management Sciences, Northwestern University, Evanston, IL, 2Department of Engineering and Applied Sciences, RAND Corporation, Arlington, VA

    *Purpose: Reducing discard is a current focus in US transplantation of deceased donor kidneys. One cause for the discards is the avoidance of protracted cold…
  • 2022 American Transplant Congress

    Site-Directed Mutagenesis as a Tool to Investigate Immunogenicity of HLA Epitopes for Humoral Alloreactivity

    C. H. Maguire1, P. Crivello2, A. Tambur1

    1Northwestern University, Chicago, IL, 2University Hospital Essen, Essen, Germany

    *Purpose: Molecular mismatch load (MML) analysis has been a proposed approach to assess donor/recipient compatibility in support of organ allocation algorithms. While conceptually appealing, MML…
  • 2022 American Transplant Congress

    A Large-Scale National Cohort Study Assessing the Impact of Diabetes and Obesity on Kidney Transplant Outcomes

    V. Rohan1, M. Casey1, S. Zemin2, P. Baliga2, D. Taber2

    1Surgery, Medical University of South Carolina, Charleston, SC, 2Medical University of South Carolina, Charleston, SC

    *Purpose: Type 2 Diabetes Mellitus (T2DM) is the most common cause of renal failure in patients undergoing kidney transplantation (KT) and highly correlated with obesity.…
  • 2022 American Transplant Congress

    Biopsy Characteristics of Kidneys from a Single Large OPO

    S. Bunnapradist1, T. Seto2, A. Cohen2, T. Rosenthal1, G. Danovitch1

    1David Geffen School of Medicine, Los Angeles, CA, 2One Legacy, Los Angeles, CA

    *Purpose: As deceased donor pool have expanded, kidney biopsy has been increasingly used to help determine organ suitability for transplant. There are concerns that biopsy…
  • 2022 American Transplant Congress

    Outcome of Pre-Emptive Kidney Transplantation in Children Under 6 Years of Age; A Single Center Experience in Japan

    Y. Aoki1, Y. Hamasaki1, J. Hashimoto1, A. Zaitsu2, M. Kubota1, M. Muramatsu1, T. Kawamura1, S. Shishido2, K. Sakai1

    1Nephrology, Toho University Faculty of Medicine, Tokyo, Japan, 2Pediatric Nephrology, Toho University Faculty of Medicine, Tokyo, Japan

    *Purpose: Kidney transplantation (KT) is the preferred treatment for pediatric end stage renal disease, and pre-emptive kidney transplantation (PEKT) may reduce morbidity and mortality. KT…
  • 2022 American Transplant Congress

    Pericardial Effusion: A Potential Late Complication of COVID-19 Infection

    O. Sogbein, A. Rizvi, M. Mujtaba, S. Hussain

    Internal Medicine, Division of Nephrology, University of Texas Medical Branch, Galveston, TX

    *Purpose: COVID-19 infection involves entry of SARS-CoV-2 virus into cells via interaction between its spike protein and angiotensin converting enzyme resulting in an NF-κβ mediated…
  • 2022 American Transplant Congress

    Defects in Kim-1 Do Not Result In Delayed Graft Function After Kidney Transplantation

    R. S. Suri1, J. Lee2, M. Ban3, B. Shrum2, O. Z. Ismail4, S. Leckie5, A. McIntyre3, Q. Xu6, S. H. Lee2, S. de Chickera2, R. A. Hegele2, L. Gunaratnam2

    1Research Institute of the McGill University Health Center, Montreal, QC, Canada, 2Schulich School of Medicine and Dentistry, Western University, Lodnon, ON, Canada, 3Robarts Research Institute, Lodnon, ON, Canada, 4University of Alberta, Edmonton, AB, Canada, 5London Health Sciences Centre, Lodnon, ON, Canada, 6University of Pittsburg Medical Center, Pittsburg, PA

    *Purpose: Tissue repair is critical to restore organ function after ischemia-reperfusion injury (IRI) during transplantation. During renal injury, upregulation of kidney injury molecule-1 (KIM-1) transforms…
  • 2022 American Transplant Congress

    Utility of Four-Point Mycophenolate Mofetil Testing in a Pediatric Kidney Transplant Population

    S. Sadiq, P. Brakeman, J. Brennan, E. Black

    Pediatric Nephrology, UCSF, San Francisco, CA

    *Purpose: While there is randomized, multicenter data in adults that area under the time concentration curve (AUC) measurements for Mycophenolate Mofetil (MMF) can direct dosing…
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