Abstracts Archive - Page 916 of 1683 - ATC Abstracts

2018 American Transplant Congress
A Single Center Outcomes Analysis of UNOS Defined "Hard to Place Kidneys"
Y. Qazi, K. Lee, A. Jones, L. Aguirre, M. Parma, M. Smogorzewski, T. T. Maw, L. Sher.
Keck Medical Center at USC, Los Angeles, CA.
The discard rate of potentially usable kidneys remains dismal despite a critical shortage of organs. The Scientific Registry of Transplant Recipients (SRTR) now provides a…
2018 American Transplant Congress
Defective Innate Immune Response to Opportunistic Pathogens in Cytomegalovirus-Infected Monocytes
P. Sen, A. R. Wilkie, R. Fernandes, R. J. Lane, S. E. Hickman, T. K. Means, E. R. Rosenberg, D. M. Coen, J. A. Fishman, J. El Khoury.
Transplant and Immunocompromised Group, Division of Infectious Diseases, Massachusetts General Hospital, Boston, MA; Department of Biological Chemistry and Pharmacology, Harvard Medical School, Boston, MA.
Human cytomegalovirus (CMV) is the most common infection encountered in transplantation and is an important cause of morbidity and mortality in both solid organ and…
2018 American Transplant Congress
Gastrointestinal Autologous Reconstruction for Management of Chronic Gut Failure in the New Era of Visceral Transplantation
K. M. Abu-Elmagd, S. R. Armanyous, N. R. Parekh, D. McMichael, M. Fujiki, K. Hashimoto, A. Khanna, A. Shatnawei, G. Costa.
Center for Gut Rehabilitation & Transplantaion, Cleveland Clinic Foundation, Cleveland, OH.
OBJECTIVE(S): Chronic gut failure(CGF) is associated with life-threatening complications, impaired life-quality, and burdened healthcare-cost. With recent advances in autologous-reconstruction along with visceral transplantation, evidence-based practical…
2018 American Transplant Congress
Organ Donation and Transplantation in US States and Europe – Is There a Benefit to Opting Out?
R. J. Vela,¹ J. Pruszynski,¹ T. Mone,³ P. Niles,² M. Peltz.¹
¹Cardiovascular & Thoracic Surgery, The University of Texas Southwestern Medical Center, Dallas, TX; ²Southwest Transplant Alliance, Dallas, TX; ³OneLegacy, Los Angeles, CA.
European reports suggest improved transplant rates in countries with Opt-out or presumed consent donation. Legislation to adopt Opt-out donation has been introduced in several US…
2018 American Transplant Congress
Hypothermic Oxygenated Machine Perfusion in Liver and Kidney Transplantation of Extended Criteria Donors: A Phase-1 of Clinical Trial
M. Ravaioli,¹ V. De Pace,¹ M. Cescon,¹ M. Del Gaudio,¹ V. R. Bertuzzo,¹ A. Siniscalchi,¹ A. D'Errico,² G. Comai,² G. La Manna,² A. D. Pinna.¹
¹General Surgery and Transplantation, University of Bologna Sant'Orsola - Malpighi Hospital, Bologna, Emilia Romagna, Italy; ²Experimental Diagnostic and Specialty Medicine, University of Bologna Sant'Orsola- Malpighi Hospital, Bologna, Emilia Romagna, Italy.
In the field of liver (LT) and kidney transplantation (KT), extended criteria donors (ECD) offer an additional organ source that is more vulnerable for early…
2018 American Transplant Congress
Maximizing Utilization in Pancreas Transplantation: Phenotypic CharacteristicsDifferentiating Aggressive from Nonaggressive Transplant Centers
O. K. Serrano,¹ D. M. Vock,² T. B. Dunn,¹ R. Kandaswamy,¹ E. B. Finger.¹
¹Surgery, University of Minnesota, Minneapolis, MN; ²Biostatistics, University of Minnesota, Minneapolis, MN.
OBJECTIVE: Given the increasing shortage of deceased donor pancreas allografts and their declining acceptance rate, maximizing utilization requires a balance between donor selection and transplant…
2018 American Transplant Congress
Depressive Symptoms, Medication Nonadherence, and Clinical Outcomes Following Lung Transplantation
M. C. Chu,¹ P. J. Smith,² G. L. Stonerock,² J. A. Blumenthal.²
¹Duke-NUS Medical School, Singapore, Singapore; ²Department of Psychiatry and Behavioral Science, Duke University Medical Center, Durham, NC.
Background:Elevated depressive symptoms have been associated with worse clinical outcomes following lung transplantation, including mortality. Few studies, however, have examined the mechanisms or clinical correlates…
2018 American Transplant Congress
mRNA Transcript Profiling of 3 Genes in Renal Allograft Biopsies (Bx) Improves Accuracy of Antibody-Mediated Rejection (ABMR) Diagnosis in Transplant Recipients Desensitized with IVIG+Rituximab+Immunoglobulin G-Degrading Enzyme of Streptococcus Pyogenes (IdeS)
H. Zhang,¹ C. Nast,² J. Doldron,² M. Cheung,² A. Vo,³ S. Jordan,³ M. Toyoda.¹
¹Transplant Immunology Laboratory, Cedars-Sinai Medical Center, Los Angeles, CA; ²Pathology and Laboratory Medicine, Cedars-Sinai Medical Center, Los Angeles, CA; ³Comprehensive Transplant Center, Cedars-Sinai Medical Center, Los Angeles, CA.
Background: Multiple molecular signatures specific to ABMR based on gene expression in renal allograft Bx of transplant recipients were reported. Here we assessed mRNA transcript…
2018 American Transplant Congress
Building a Third-Party VST Bank from Scratch- The Cincinnati Experience
A. S. Nelson,¹ D. Heyenbruch,² X. Zhu,³ S. M. Davies,¹ C. Lutzko,³ C. Bollard,⁴ P. Hanley,⁴ T. Leemhuis,² L. Danziger-Isakov,⁵ M. S. Grimley.¹
¹Bone Marrow Transplant & Immune Deficiency, Cincinnati Children's Hospital Medical Center, Cincinnati, OH; ²Hoxworth Blood Center, Univeristy of Cincinnati, Cincinnati, OH; ³Experimental Hematology & Cancer Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH; ⁴Proram for Cell Enhancement and Technologies for Immunotherapy, Children's National Health System, Washington, DC; ⁵Depatment of Infectious Diseases, Cincinnati Children's Hospital Medical Center, Cincinnati, OH.
BackgroundViral infections remain a challenge to treat and significantly contribute to morbidity and mortality. Virus specific T cells (VSTs) have shown clinical efficacy, with minimal…
2018 American Transplant Congress
The AKI-Predict-Score: A New Prediction Model for Acute Kidney Injury after Liver Transplantation
M. Kalisvaart,¹ A. Schlegel,¹ I. Umbro,² K. Roberts,¹ D. Mirza,¹ T. Perera,¹ J. Isaac,¹ A. P. Mitterhofer,² J. de Jonge,³ P. Muiesan.¹
¹Liver Unit, Queen Elizabeth Hospital, Birmingham, United Kingdom; ²Internal Medicine, Sapienza University, Rome, Italy; ³Surgery, Erasmus MC University Medical Center, Rotterdam, Netherlands.
BackgroundPostoperative acute kidney injury (AKI) is a frequent complication after liver transplantation and associated with impaired survival rates, chronic kidney disease and higher costs. Although…