ATC Abstracts

American Transplant Congress abstracts

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  • 2022 American Transplant Congress

    De Novo Focal Segmental Glomerulosclerosis in the Kidney Allograft: Association with Alloimmunity Leading to Poor Outcome

    J. Leon1, J. Duong Van Huyen2, A. Abderrahmane1, D. Anglicheau1, C. Legendre1, M. Rabant2

    1KIDNEY TRANSPLANTATION, Necker Hospital, Paris, France, 2KIDNEY PATHOLOGY, Necker Hospital, Paris, France

    *Purpose: Focal Segmental Glomerulosclerosis (FSGS) can be found de novo (Dn) or as a recurrence in kidney allograft. While FSGS recurrence has been extensively described…
  • 2022 American Transplant Congress

    Association Between CT Measurements of Body Composition Before Liver Transplantation and Post-Transplantation Outcomes

    Y. Liu1, O. Shafaat1, K. Jackson1, J. Motter1, B. Boyarsky1, M. Latif1, F. Yuan1, E. King1, A. Zaheer1, R. Summers2, D. Segev1, M. McAdams-DeMarco1, C. Weiss1

    1Johns Hopkins University, Baltimore, MD, 2NIH Clinical Center, Bethesda, MD

    *Purpose: Various methods exist for measuring body composition using computed tomography (CT) scans; however, it is unclear which components best predict post-liver transplantation (LT) outcomes.…
  • 2022 American Transplant Congress

    Defining the Characteristics and Graft Outcomes of Kidney Transplant Recipients with Pre-Transplant Elevated Plasma Oxalate Levels

    D. Khan, N. Zhang, M. Keddis

    Mayo Clinic, Scottsdale, AZ

    *Purpose: The objective of this study is to compare graft outcomes for patients with pre-transplant elevated plasma oxalate (Pox) compared to a matched cohort.*Methods: Kidney…
  • 2022 American Transplant Congress

    Invasive Fungal Infections Associated with COVID-19 Infections in Solid Organ Transplant Recipients

    R. Alameer, M. Nguyen, P. Samanta

    Infectious Diseases, University of Pittsburgh Medical Center, Pittsburgh, PA

    *Purpose: Invasive fungal infection (IFI) complicating Coronavirus disease of 2019 (COVID-19) has been increasingly recognized. IFI is a common opportunistic infection in solid organ transplant…
  • 2022 American Transplant Congress

    The Impact of Frailty Syndrome on Humoral Response to SARS-CoV-2 mRNA Vaccines in Older Kidney Transplant Recipients

    M. Schmalz1, H. Vankova2, S. Rajnochova-Bloudickova1, P. Hruba3, M. Fialova4, J. Gurka5, M. Magicova1, I. Striz4, I. Zahradka1, O. Viklicky1

    1Department of Nephrology, Institute for Clinical and Experimental Medicine, Prague, Czech Republic, 2The Third Faculty of Medicine, Charles University, Prague, Czech Republic, 3Transplantation Laboratory, Institute for Clinical and Experimental Medicine, Prague, Czech Republic, 4Department of Immunology, Institute for Clinical and Experimental Medicine, Prague, Czech Republic, 5Department of Information Technology, Institute for Clinical and Experimental Medicine, Prague, Czech Republic

    *Purpose: Advanced age is associated with impaired humoral immune response to SARS-CoV-2 mRNA vaccines in kidney transplant recipients (KTR), however mechanisms are poorly understood. Frailty…
  • 2022 American Transplant Congress

    Practices and Perceptions of Living Donor Liver Transplant, Non-Directed Donation, and Liver Paired Exchange: A National Survey

    A. Kaplan1, R. Rosenblatt1, W. Jackson2, R. Brown1, B. Samstein1

    1New York Presbyterian Weill Cornell, New York, NY, 2University of Colorado Denver, Denver, CO

    *Purpose: Living donor liver transplant (LDLT) remains under-utilized in the United States. The aim of this study, therefore, was to assess the perceptions and practices…
  • 2022 American Transplant Congress

    Improving Efficiency in Kidney Distribution: A Comparison of UNet Deceased Donor Criteria to Actual Kidney Acceptance Practices

    L. B. Zeiser, J. Ruck, D. Segev, A. Massie

    Johns Hopkins University, Baltimore, MD

    *Purpose: Efficient utilization of UNet deceased-donor criteria could help streamline kidney allocation by reducing the number of unwanted offers made to transplant centers. We compared…
  • 2022 American Transplant Congress

    Early Post-Operative Thrombotic Microangiopathy in Deceased Donor Kidney Transplant: A Retrospective Case Series

    R. Seneriz1, A. Mattiazzi1, G. Guerra1, T. Harrington2, M. Velasquez3

    1Miami Transplant Institute, Miami, FL, 2University of Miami, Miami, FL, 3Jackson Memorial Hospital, Miami, FL

    *Purpose: Transplant associated thrombotic microangiopathy (TA-TMA) is characterized by endothelial injury along with thrombocytopenia, microangiopathic hemolytic anemia (MAHA) and kidney graft dysfunction. It can be…
  • 2022 American Transplant Congress

    Natural Killer Cell NKG2D Receptor Mediates Airway Cell Hypoxic Injury Through Recognition of Stress Molecules

    T. Tsao1, E. Aminian1, A. Shemesh1, L. Tran1, P. Wang1, F. Deiter1, J. R. Greenland2, D. R. Calabrese1

    1University of California, San Francisco, San Francisco, CA, 2Medicine, University of California, San Francisco, CA

    *Purpose: Primary graft dysfunction (PGD), the clinical syndrome of pulmonary hypoxia and reperfusion, occurs afer 1/3 of all lung transplants, and accounts for excess mortality.…
  • 2022 American Transplant Congress

    Longitudinal Analysis of Donor-Derived Cell-Free DNA (dd-cfDNA) in En-Bloc Kidney Transplantation

    S. K. Akkina1, J. Klein2, A. Khalil3, G. Shekhtman4, S. Patel4, N. Agrawal4, M. Fei4, N. Singh5, A. Desai1

    1Loyola University Medical Center, Maywood, IL, 2University of Kansas Medical Center, Kansas City, KS, 3Dallas Nephrology Associates, Dallas, TX, 4CareDx, Brisbane, CA, 5Willis Knighton Health System, Shreveport, LA

    *Purpose: The longitudinal dd-cfDNA patterns in en-bloc kidney transplant recipients have not been studied. It is unknown how the initial smaller mass of the two…
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