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American Transplant Congress abstracts

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  • 2022 American Transplant Congress

    Improving Efficiency in Kidney Distribution: A Comparison of UNet Deceased Donor Criteria to Actual Kidney Acceptance Practices

    L. B. Zeiser, J. Ruck, D. Segev, A. Massie

    Johns Hopkins University, Baltimore, MD

    *Purpose: Efficient utilization of UNet deceased-donor criteria could help streamline kidney allocation by reducing the number of unwanted offers made to transplant centers. We compared…
  • 2022 American Transplant Congress

    Impact of Donor Quality on Outcomes for AKI and Non-AKI Kidneys with and without DGF

    C. Jadlowiec1, P. Budhiraja2, R. Butterfield1, M. Smith3, A. K. Mathur1, A. Moss1, H. Khamash2, K. Reddy1, R. Heilman2

    1Mayo Clinic Arizona, Phoenix, AZ, 2Division of Transplant Nephrology, Mayo Clinic Arizona, Phoenix, AZ, 3Division of Anatomic Pathology, Mayo Clinic Arizona, Phoenix, AZ

    *Purpose: The relevance of DGF, and whether it is clinically significant, continues to be debated. Our aim was to compare post-transplant outcomes between AKI and…
  • 2022 American Transplant Congress

    A Third Dose of SARS-CoV-2 Vaccine Increases Neutralizing Antibodies Against Variants of Concern in Solid Organ Transplant Recipients

    A. H. Karaba1, X. Zhu1, T. Ling1, K. H. Wang1, A. G. Rittenhouse1, O. Akinde1, Y. Eby1, J. E. Ruff1, J. N. Blankson1, A. T. Abedon1, J. L. Alejo1, A. L. Cox1, J. R. Bailey1, E. A. Thompson1, S. L. Klein1, D. S. Warren1, J. M. Garonzik-Wang2, B. J. Boyarsky1, I. Sitaras1, A. Pekosz1, D. L. Segev1, A. A. Tobian1, W. A. Werbel1

    1Johns Hopkins University, Baltimore, MD, 2University of Wisconsin School of Medicine and Health, Madison, WI

    *Purpose: Vaccine-induced SARS-CoV-2 antibody responses are attenuated in solid organ transplant recipients (SOTRs) and breakthrough infections are more common. Additional SARS-CoV-2 vaccine doses increase anti-spike…
  • 2022 American Transplant Congress

    Graft and Patient Outcomes of Kidney Transplant Tourism: A Single-Center Experience

    A. Altheaby1, R. Algain2, R. Salem2, A. Alotaibi2, K. Owaidah2, M. Tawahri1, M. Shaheen3, Z. Arabi4

    1Nephrology, King Abdulaziz Medical City-NGHA, Riyadh, Saudi Arabia, 2Internal Medicine, King Abdulaziz Medical City-NGHA, Riyadh, Saudi Arabia, 3King Saud Bin Abdulaziz for Health Sciences, Riyadh, Saudi Arabia, 4Renal Transplant, King Abdulaziz Medical City-NGHA, Riyadh, Saudi Arabia

    *Purpose: The expanding supply-demand mismatch between organs available for transplantation and patients in need led to the growth of transplant tourism. In our study, we…
  • 2022 American Transplant Congress

    An Acceptable Challenge for Specialized Transplant Centres: Small Kidney Donors for Small Recipients

    R. Büscher, M. Cetiner, P. F. Hoyer, A. K. Büscher

    Department of Pediatrics II, University Hospital Essen, Essen, Germany

    *Purpose: Kidneys from small donors (SDK, donor weight
  • 2022 American Transplant Congress

    The Impact of Frailty Syndrome on Humoral Response to SARS-CoV-2 mRNA Vaccines in Older Kidney Transplant Recipients

    M. Schmalz1, H. Vankova2, S. Rajnochova-Bloudickova1, P. Hruba3, M. Fialova4, J. Gurka5, M. Magicova1, I. Striz4, I. Zahradka1, O. Viklicky1

    1Department of Nephrology, Institute for Clinical and Experimental Medicine, Prague, Czech Republic, 2The Third Faculty of Medicine, Charles University, Prague, Czech Republic, 3Transplantation Laboratory, Institute for Clinical and Experimental Medicine, Prague, Czech Republic, 4Department of Immunology, Institute for Clinical and Experimental Medicine, Prague, Czech Republic, 5Department of Information Technology, Institute for Clinical and Experimental Medicine, Prague, Czech Republic

    *Purpose: Advanced age is associated with impaired humoral immune response to SARS-CoV-2 mRNA vaccines in kidney transplant recipients (KTR), however mechanisms are poorly understood. Frailty…
  • 2022 American Transplant Congress

    The Effect of Adoption of Acuity Circles on Hepatocellular Carcinoma Transplantation Rates at a Single High Acuity Center

    D. W. Victor III, J. Corkrean, S. Kodali

    Sherrie and Allan Conover Center for Liver disease and Transplantation, Houston Methodist Hospital, Houston, TX

    *Purpose: Transplantation for selected patient with HCC has been prioritized with a MELD exception since 2002. Further changes have decreased the maximum exception for HCC.…
  • 2022 American Transplant Congress

    National Attitudes Towards Early Liver Transplantation for Alcoholic Liver Disease

    J. Mitchell1, K. Nijhar1, K. Herrick-Reynolds2, H. Sung1, P. Chen1, D. L. Segev1, E. King1, A. Cameron1

    1Department Of Surgery, Johns Hopkins University, Baltimore, MD, 2Department Of Surgery, Walter Reed National Military Medical Center, Bethesda, MD

    *Purpose: Pre-transplant abstinence requirements, notably the 6-month sobriety guideline, limit access to liver transplant for patients with severe alcoholic hepatitis (SAH). This study examines the…
  • 2022 American Transplant Congress

    Low-Quality Kidney Allograft Use in Kidney Transplantation is Associated with a Prolonged Post-Transplant Length of Stay

    J. A. Kahla1, C. R. Goff1, J. A. Goss2, A. A. Rana2

    1Department of Student Affairs, Baylor College of Medicine, Houston, TX, 2Division of Abdominal Transplantation, Michael E DeBakey Department of General Surgery, Baylor College of Medicine, Houston, TX

    *Purpose: The purpose of this study is to determine the effect of low-quality kidney allografts on recipient hospital length of stay following transplant using five…
  • 2022 American Transplant Congress

    HLA-II Subclasses Behave Differently Between Themselves and Between Humans: Cues to Understand Alloreactivity

    S. Beland, O. Desy, M. Marcoux, M. Thivierge, J. Desgagnes, S. A. De Serres

    Transplantation Unit, Renal Division, University Health Center of Quebec, Faculty of Medicine, Universite Laval, Quebec, QC, Canada

    *Purpose: De novo anti-HLA-II DSAs (dnDSA) are associated with antibody-mediated rejection. However, some patients with anti-HLA-II DSAs will not develop rejection, suggesting that the development…
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