2018 American Transplant Congress
Assessing the Impact of Flow in Hypothermic Machine Perfusion on Human Venous Endothelium Using a Novel Ex Vivo Model
BACKGROUNDHypothermic machine perfusion (HMP) involves dynamic flow of chilled preservation fluid through an allograft's vasculature. This study describes a simple, reproducible, human model that allows…2018 American Transplant Congress
Human Endothelial-Like Cells Transdifferentiated from Peripheral CD14+ Monocytes Inhibit T Cells in Response to Allo-Stimulation
Gastroenterological and Transplant Surgery, Hiroshima University, Hiroshima, Japan.
We have previously demonstrated that the endothelial cells located in immune-privilege sites, such as livers, suppress T-cells in response to both of direct and indirect…2018 American Transplant Congress
A Novel Endothelial Cell Based Complement Dependent Cytotoxicity Test in Kidney Transplantation
Introduction:Relevant alloantibodies in kidney transplantation comprise anti-HLA antibodies, blood group antibodies (ABO incompatible) and anti-endothelial cell antibodies (AECA) and can initiate antibody-mediated rejection (ABMR). ABMR…2018 American Transplant Congress
Targeting LTβR Classical NFκB Signaling Facilitates Inflammation Resolution
Background:Contact hypersensitivity (CHS) is a reliable model to assess the immune cell-mediated cutaneous inflammatory response, which includes the three phases of priming/sensitization, elicitation, and resolution,…2018 American Transplant Congress
Early Utilization of Telehealth in Kidney Transplantation
Transplant Institute, University Hospitals of Cleveland, Cleveland, OH.
Introduction: Telehealth is an emerging strategy to improve outcomes and decrease emergency department visits and readmissions. Utility of telehealth in kidney transplantation hasn't been much…2018 American Transplant Congress
Malignancies in Kidney Transplant Recipients: A Long-Term Observational Study
Nephrology and Internal Intensive Care, Charite Universitaetsmedizin Berlin, Berlin, Germany.
Background: Previous studies have shown increased incidence of malignancies in patients after kidney transplantation. However, most of the existing data on post-transplant malignancies is limited…2018 American Transplant Congress
Timeline and Histopathological Characteristics of Graft Failure after Kidney Transplantation: What is Preventable and What is Not?
University of Wisconsin, Madison.
Background: There is limited information on the histopathological characteristics of kidney transplant recipients (KTRs) with graft failure at different post-transplant time intervals. Methods:We addressed this…2018 American Transplant Congress
Urine Pellet Podocyte mRNAs Correlate Closely with Late Kidney Allograft Loss-of-Function
1Univ Michigan, Ann Arbor; 2Univ Kansas, Kansas City.
10-year surveillance biopsy studies (Nankivell,2003 & Stegall,2017) and podometric studies are compatible with progressive glomerulosclerosis (GS) contributing to long-term allograft loss-of-function.Thus one would expect to…2018 American Transplant Congress
Does DGF Result in Worse Outcomes in a Second Transplant?
Delayed graft function (DGF) is a risk factor for patient death, kidney allograft loss, reduced allograft function and acute rejection after kidney transplantation. Prior transplant…2018 American Transplant Congress
Comprehensive Assessment of NSAID Use and Potential Nephrotoxicity Risk in Adult Veteran Kidney Transplant Recipients
Ralph H Johnson VAMC, Charleston, SC.
Background: NSAID use is generally recommended to be avoided in kidney transplantation (KTX), but there is paucity in the studies assessing their safety within this…
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