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American Transplant Congress abstracts

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  • 2022 American Transplant Congress

    Risk Factors for Early Post Transplant Cardiac Dysfunction After Liver Transplantation

    V. Subramanian1, K. Bowers2, H. Kalagotla2, J. Buggs1, N. Kemmer1, K. Dhanireddy1

    1Transplant Institute, Tampa General Hospital, Tampa, FL, 2University of South Florida, Tampa, FL

    *Purpose: Cardiovascular complications after liver transplantation (LTx) are a leading cause of morbidity and mortality. The goal of this study was to evaluate risk factors…
  • 2022 American Transplant Congress

    Sars-cov-2 Antibody and T Cell Response After Vaccination with or without Intensified Immunosuppression Among Pediatric Renal Transplant Recipients

    H. Pizzo1, B. Shin2, P. R. Soni3, S. Nadipuram3, J. Garrison2, R. Zhang2, S. C. Jordan2, D. Puliyanda1

    1Pediatric Nephrology, Cedars-Sinai Medical Center, Los Angeles, CA, 2Comprehensive Transplant Center, Cedars-Sinai Medical Center, Los Angeles, CA, 3Pediatric Infectious Disease, Cedars-Sinai Medical Center, Los Angeles, CA

    *Purpose: Recent data has shown poor antibody response to SARS-CoV-2 vaccination among adult kidney transplant (tx) recipients, with seroconversion ranging between 22%-58% after two mRNA…
  • 2022 American Transplant Congress

    Transition Program for Young Adults with Solid Organ Transplant a Single Center Protocol

    H. Y. Lee

    Program for Pediatric Cardiomyopathy, Heart Failure, and Cardiac Transplantation, Columbia University Irving Medical Center, New York, NY

    *Purpose: The transition process for young adult solid organ transplant patient is an important clinical milestone in a transplant patient's life. Evidenced based research demonstrates…
  • 2022 American Transplant Congress

    De Novo DSA in the Setting of Stable Allograft Function is a Benign Finding

    R. J. Knight, E. A. Graviss, D. T. Nguyen, T. N. Eagar, S. G. Yi, H. Podder, M. Hobeika, R. McMillan, A. O. Gaber

    Houston Methodist Hospital, Houston, TX

    *Purpose: We sought to determine the long-term outcome of renal allografts that developed de novo DSA (dnDSA) in the setting of stable renal function.*Methods: A…
  • 2022 American Transplant Congress

    Recipient Treatment with Anti-CD122 mAb Prolongs Kidney Allograft Survival During Antibody-Mediated Rejection without Impacting NK Cell Activation within the Graft

    D. Okada, S. Miyairi, N. Dvorina, K. S. Keslar, A. Valujskikh, W. Baldwin, R. Fairchild

    Cleveland Clinic, Cleveland, OH

    *Purpose: Dysregulated donor-specific antibody (DSA) responses are induced in B6.CCR5-/- mice transplanted with complete MHC mismatched kidney allografts and are required for rejection of the…
  • 2022 American Transplant Congress

    Treatment Modality and Outcomes of Antibody-Mediated Rejection in Pediatric Kidney Transplant Recipients: The PARAMOUr Study

    R. Engen1, A. Jain2, N. Hayde3, A. Mansuri4, M. Kallash5, S. McEwen6, R. Garro7, C. Peterson8, R. Zahr9, L. Harshman10, D. Puliyanda11, S. Solomon12, K. Twombley13, I. Ashoor14

    1Pediatrics, University of Wisconsin Madison, Madison, WI, 2Wayne State University, Detroit, MI, 3Albert Einstein College of Medicine, New York, NY, 4Augusta University, Augusta, GA, 5The Ohio State University, Columbus, OH, 6University of Minnesota, Minneapolis, MN, 7Emory University, Atlanta, GA, 8University of Utah Health, Salt Lake City, UT, 9The University of Tennessee Health Science Center, Memphis, TN, 10University of Iowa, Iowa City, IA, 11Cedars-Sinai Medical Center, Los Angeles, CA, 12New York Medical College, Valhalla, NY, 13Medical University of South Carolina, Charleston, SC, 14Louisiana State University, New Orleans, LA

    *Purpose: Antibody-mediated rejection (AMR) is the leading cause of graft failure in kidney transplantation, but evidence for effective treatments is limited.*Methods: PARAMOUr is a retrospective…
  • 2022 American Transplant Congress

    Baseline Findings from the UREAACT Trial to Improve Medication Adherence in Youth with Kidney Transplants

    S. Amaral1, P. Kwong2, J. Zhu2, R. George3, N. Rodig4, B. Warady5, J. Smith6, A. Bobrowski7, D. Matossian8, N. Zelikovsky9, L. Schwartz1, P. Reese2, R. Goldfarb Terry1, J. Reason2, A. Chung1, S. Furth1

    1CHOP, Phila, PA, 2UPenn, Phila, PA, 3CHOA, Atlanta, GA, 4Boston Children's, Boston, MA, 5Children's Mercy, Kansas City, MO, 6Seattle Children's, Seattle, WA, 7Cleveland Clinic, Cleveland, OH, 8Lurie Children's, Chicago, IL, 9LaSalle Univ, Phila, PA

    *Purpose: This abstract describes the design and baseline characteristics of participants in the U-REAACT trial, a study to improve medication adherence in youth with kidney…
  • 2022 American Transplant Congress

    Functional Recellularized Patient Derived Endothelium; A Human Vascular Graft Approach

    H. Tejeda Mora1, J. Willemse2, Y. den Hartog1, I. Schurink2, M. M. Verstegen2, J. de Jonge2, R. C. Minnee2, M. W. van den Hoogen2, C. C. Baan1, L. J. van der Laan2, M. J. Hoogduijn1

    1Transplant Institute - Internal Medicine, Erasmus Medical Center, Rotterdam, Netherlands, 2Transplant Institute - Department of Surgery, Erasmus Medical Center, Rotterdam, Netherlands

    *Purpose: In transplantation, the endothelial lining is the first barrier between the donor organ and recipient immune system. Damaged endothelium exposes extracellular matrix (ECM) molecules…
  • 2022 American Transplant Congress

    Steatosis Following Liver Transplantation for Nonalcoholic Steatohepatitis is Associated with a Higher Rate of Cardiovascular Complications

    W. Alhamoudi1, S. Alqahtani2, K. Bzeizi2, A. Albenmousa2, Y. Saleh2, D. Broering2, S. Alghamdi2

    1Medicine, King Saud University, Riyadh, Saudi Arabia, 2Liver Transplantation, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia

    *Purpose: Cirrhosis secondary to Nonalcoholic Steatohepatitis (NASH) is projected to become the leading indication for liver transplantation (LT) worldwide. Objectives: to evaluate the prevalence of…
  • 2022 American Transplant Congress

    Characteristics and Outcomes of Anhepatic Patients Listed for Liver Retransplantation

    R. G. Kathawate1, T. Ibeabuchi2, P. Abt2, T. Bittermann2

    1University of Michigan, Ann Arbor, MI, 2University of Pennsylvania, Philadelphia, PA

    *Purpose: The frequency and outcomes of anhepatic patients listed for transplantation in the United States has not been previously described. The United Network for Organ…
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