ATC Abstracts

American Transplant Congress abstracts

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  • 2022 American Transplant Congress

    Dietary Sodium Intake And Blood Pressure In Living Kidney Donors (SPLID): Rationale And Design Of A Pilot Single-center Crossover Single-blind Randomized Controlled Trial

    E. Tantisattamo1, U. G. Reddy1, A. J. Ferrey1, H. Ichii2, D. C. Dafoe2, H. Moradi1, C. M. Rhee1, K. Kalantar-Zadeh1

    1Division of Nephrology, Hypertension and Kidney Transplantation, Department of Medicine, University of California Irvine School of Medicine, Orange, CA, 2Division of Kidney and Pancreas Transplantation, Department of Surgery, University of California Irvine School of Medicine, Orange, CA

    *Purpose: Since living kidney donors(LKD) are generally healthy and non-hypertensive individuals, non-pharmacologic interventions are likely to be an acceptable and practical approach to preventing hypertension(HTN).…
  • 2022 American Transplant Congress

    Enhancing Early Nerve Regeneration from Reconstruction of a Segmental Nerve Injury with Polyethylene Glycol

    A. Bernal1, C. Hinshaw1, J. Hinshaw1, C. Yang2, S. Margaux1, W. Zhang1, J. Nuelle1, C. Sabbag1, G. Bittner2, J. Shores3, E. Weitzel1, J. Alderete1

    1RESTOR FUSE Nerve Reconstruction Consortium, US Army Institute of Surgical Research/59th MDW, San Antonio, TX, 2University of Texas at Austin, Austin, TX, 3John Hopkins University, Baltimore, MD

    *Purpose: Despite advancements in understanding and treating peripheral nerve injuries (PNIs), restoration of lost motor and sensory functions remain poor using current methods of clinical…
  • 2022 American Transplant Congress

    Liver Transplantation for Primary Sclerosing Cholangitis (psc): Experience from the Last Three Decades

    J. Zhu1, D. Lim1, L. James1, E. Yoshida2, K. Peltekian1

    1Medicine, Dalhousie University, Halifax, NS, Canada, 2Medicine, University of British Columbia, Vancouver, BC, Canada

    *Purpose: In liver transplantation (LT) for PSC, pre-transplant colectomy may lower the risk of PSC recurrence (rPSC), and well-controlled or lack of IBD may protect…
  • 2022 American Transplant Congress

    Stem Cell Donor-Derived CPRA Better Reflects Sensitization Than Current CPRA

    K. Lindblad1, C. Murphey2, P. Lalli3, J. Lunz4, L. Gragert5

    1UNOS, Richmnd, VA, 2Southwest Immunodiagnostics, Inc., San Antonio, TX, 3Carolinas Medical Center, Charlotte, NC, 4LifeLink Foundation Transplant Immunology Lab, Tampa, FL, 5Tulane University School of Medicine, New Orleans, LA

    *Purpose: The OPTN Histocompatibility Committee proposes replacing the current calculated panel reactive antibody (CPRA), based on HLA haplotype frequencies from ~14,000 deceased kidney donors, with…
  • 2022 American Transplant Congress

    Post-Kidney Transplant Body Mass Index Trajectories Are Associated with Graft Loss and Mortality

    Y. Liu1, V. Bendersky1, X. Chen1, M. Harhay2, D. Segev1, M. McAdams-DeMarco1

    1Johns Hopkins University, Baltimore, MD, 2Drexel University, Philadelphia, PA

    *Purpose: Early post-kidney transplantation (KT) changes in physiology, medications, and health stressors likely impact body mass index (BMI). Hence, we sought to estimate trajectories of…
  • 2022 American Transplant Congress

    Novel Biopsy-Based Clinical Phenotype Clustering to Predict Kidney Transplant Outcomes

    A. Ahmed1, L. Allegretti2, C. Rebello3, B. Kinsella3, K. Guo3, S. Park4, J. Friedewald3

    1Chicago Medical School at Rosalind Franklin University, Chicago, IL, 2University of Wisconsin, Madison, WI, 3Northwestern University, Chicago, IL, 4Transplant Nephrology, Northwestern University, Chicago, IL

    *Purpose: The purpose of this study was to define novel clinical phenotypes based on biopsy results to enhance biomarker discovery.*Methods: Retrospective analysis of kidney biopsy…
  • 2022 American Transplant Congress

    Impact of Delayed Graft Function in Donation After Circulatory Death Kidney Transplantation

    J. Mello Offerni1, H. Brar1, D. Lee1, M. Levine2, M. Mandurah1, S. Rim1, A. Sener1, P. Luke1

    1Urology, Western University, London, ON, Canada, 2Division of Urology, Department of Surgery, University of Alberta, Edmonton, AB, Canada

    *Purpose: Donation after circulatory death (DCD) has been associated with higher rates of delayed graft function (DGF) when compared to donation after brain death (DBD).…
  • 2022 American Transplant Congress

    Dual Deceased Donor Kidney Transplants: Maximizing Utilization of Suboptimal Kidneys

    S. Nagaraju, S. Vaishnav, K. Boggs, T. Cook, A. Jones, J. B. Africa

    Renal Transplant, Charleston Area Medical Center, Charleston, WV

    *Purpose: To demonstrate that dual transplant of marginal kidneys is an underutilized strategy to minimize discard rates and mitigate organ shortage.*Methods: We compared dual kidney…
  • 2022 American Transplant Congress

    Bioink Based on the DECM for 3D-Bioprinting of Bionic Pancreas – First Results of Animal

    M. Klak1, K. Kosowska1, T. Bryniarski1, I. Lojszczyk1, T. Dobrzanski2, G. Tymicki1, A. Filip1, A. A. Szczepankiewicz3, R. Olkowski4, A. Kosowska4, A. Berman1, A. Kaminski4, M. Wszola1

    1Foundation of Research and Science Development, Warsaw, Poland, 2Polbionica LTD, Warsaw, Poland, 3Institute of Experimental Biology M. Nencki PAN, Warsaw, Poland, 4Medical University of Warsaw, Warsaw, Poland

    *Purpose: Tissue engineering is an interdisciplinary field involving activities based on two interrelated areas: developing new methods to repair, regenerate and replace damaged tissues and…
  • 2022 American Transplant Congress

    Donor-Derived Cell-Free DNA Testing in Kidney Transplantation: Do One-Month Values Have Any Prognostic Significance?

    B. K. Sharda1, M. Garner1, A. Farney1, G. Orlando2, J. Rogers2, C. Jay3, A. Daniel1, A. Guiterrez1, N. Sakhovskaya1, R. Stratta1

    1ATRIUM HEALTH Wake Forest Baptist Medical Center, Winston Salem, NC, 2Wake Forest Baptist Medical Center, Winston Salem, NC, 3Wake Forest Baptist Health, Winston-Salem, NC

    *Purpose: Plasma-based donor-derived cell-free DNA (dd-cfDNA) assays have been proposed as an alternative to percutaneous renal allograft biopsy which is the current gold standard for…
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