ATC Abstracts

American Transplant Congress abstracts

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  • 2022 American Transplant Congress

    Final Flow and Resistance During Cold Pulsatile Perfusion Preservation Do Have Value in Prediction of Deceased Donor Graft Survival After Adjusting for KDPI

    D. S. Keith, E. Lessmann

    Kidney Transplant, Sacred Heart Hospital, Pensacola, FL

    *Purpose: To determine whether cold pulsatile perfusion preservation (CPPP) parameters of flow and resistance provide additional data regarding deceased donor kidney graft survival after adjusting…
  • 2022 American Transplant Congress

    Regulation of Cell Death During Cold Preservation of Marginal Human Kidneys

    J. R. DiRito1, G. Chickering1, J. Langford1, D. Stern1, D. Qin2, S. Hosgood3, M. Nicholson3, J. Pober4, E. Gavathiotis5, R. Kitsis5, G. Tietjen1

    1Surgery, Yale School of Medicine, New Haven, CT, 2Albert Einstein College of Medicine, Bronx, NY, 3Surgery, University of Cambridge, Cambridge, United Kingdom, 4Immunology, Yale School of Medicine, New Haven, CT, 5Albert Einstein College of Medicine, Bronx, NM

    *Purpose: Each year thousands of kidneys from marginal donors are discarded due to an increased sensitivity to injury during cold storage and consequently a high…
  • 2022 American Transplant Congress

    Stem Cell Donor-Derived CPRA Better Reflects Sensitization Than Current CPRA

    K. Lindblad1, C. Murphey2, P. Lalli3, J. Lunz4, L. Gragert5

    1UNOS, Richmnd, VA, 2Southwest Immunodiagnostics, Inc., San Antonio, TX, 3Carolinas Medical Center, Charlotte, NC, 4LifeLink Foundation Transplant Immunology Lab, Tampa, FL, 5Tulane University School of Medicine, New Orleans, LA

    *Purpose: The OPTN Histocompatibility Committee proposes replacing the current calculated panel reactive antibody (CPRA), based on HLA haplotype frequencies from ~14,000 deceased kidney donors, with…
  • 2022 American Transplant Congress

    Bioink Based on the DECM for 3D-Bioprinting of Bionic Pancreas – First Results of Animal

    M. Klak1, K. Kosowska1, T. Bryniarski1, I. Lojszczyk1, T. Dobrzanski2, G. Tymicki1, A. Filip1, A. A. Szczepankiewicz3, R. Olkowski4, A. Kosowska4, A. Berman1, A. Kaminski4, M. Wszola1

    1Foundation of Research and Science Development, Warsaw, Poland, 2Polbionica LTD, Warsaw, Poland, 3Institute of Experimental Biology M. Nencki PAN, Warsaw, Poland, 4Medical University of Warsaw, Warsaw, Poland

    *Purpose: Tissue engineering is an interdisciplinary field involving activities based on two interrelated areas: developing new methods to repair, regenerate and replace damaged tissues and…
  • 2022 American Transplant Congress

    Dietary Sodium Intake And Blood Pressure In Living Kidney Donors (SPLID): Rationale And Design Of A Pilot Single-center Crossover Single-blind Randomized Controlled Trial

    E. Tantisattamo1, U. G. Reddy1, A. J. Ferrey1, H. Ichii2, D. C. Dafoe2, H. Moradi1, C. M. Rhee1, K. Kalantar-Zadeh1

    1Division of Nephrology, Hypertension and Kidney Transplantation, Department of Medicine, University of California Irvine School of Medicine, Orange, CA, 2Division of Kidney and Pancreas Transplantation, Department of Surgery, University of California Irvine School of Medicine, Orange, CA

    *Purpose: Since living kidney donors(LKD) are generally healthy and non-hypertensive individuals, non-pharmacologic interventions are likely to be an acceptable and practical approach to preventing hypertension(HTN).…
  • 2022 American Transplant Congress

    Normothermic Organ Preservation: The New Standard?

    K. Mistry

    Sanford Health, Fargo, ND

    *Purpose: Normothermic perfusion (NMP) is a new technique that has been introduced into transplantation expanding capacity for organ utilization. NMP has been shown to be…
  • 2022 American Transplant Congress

    Outcomes Following Renal Transplant with Hepatitis C Viremic Donors in an Elderly Veteran Population with Preemptive Mayvret Therapy

    R. Lopez-Soler1, A. Thorndyke1, C. Trotter1, A. Abadier2, M. Samra1

    1Surgery, Transplantation, Edward Hines Jr. Veterans Administration Hospital, Hines, IL, 2Surgery, Loyola University School of Medicine, Maywood, IL

    *Purpose: Overall mortality on the kidney transplant waiting list is higher for older diabetic patients. The average age of waitlisted veteran patients is 64, with…
  • 2022 American Transplant Congress

    QSant, a Novel Urine Test Monitors Recovery of Allograft Injury After DGF

    S. Ghosh1, H. Tedesco2, R. Sarwal1, N. Titzler1, W. Yazar1, M. Nakamura2, J. Pestana2, M. Sarwal1

    1Nephrosant, Brisbane, CA, 2Hospital do Rim, Sao Paolo, Brazil

    *Purpose: We evaluate urine QSant assay to non-invasively monitor recovery of allograft injury, post delayed graft function(DGF).*Methods: 65 HLA-DR matched, renal allograft recipients, on TAC/MMF/prednisone…
  • 2022 American Transplant Congress

    Dual Deceased Donor Kidney Transplants: Maximizing Utilization of Suboptimal Kidneys

    S. Nagaraju, S. Vaishnav, K. Boggs, T. Cook, A. Jones, J. B. Africa

    Renal Transplant, Charleston Area Medical Center, Charleston, WV

    *Purpose: To demonstrate that dual transplant of marginal kidneys is an underutilized strategy to minimize discard rates and mitigate organ shortage.*Methods: We compared dual kidney…
  • 2022 American Transplant Congress

    PACAP-Mediated Autophagy Prevents Liver Ischemia Reperfusion Injury in OLT

    Z. Xue, B. Yang, R. Busuttil, J. Kupiec-Weglinski, H. Ji

    UCLA Medical Center, Los Angeles, CA

    *Purpose: Pituitary adenylate cyclase-activating polypeptide (PACAP) is from vasoactive intestinal peptide-glucagon-secretin family. Our group was the first to demonstrate that neuropeptide PACAP, which innervates the…
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