Abstracts Archive - Page 77 of 1683 - ATC Abstracts

2022 American Transplant Congress
Gsk3beta Regulates the Resolution of Liver Ischemia Reperfusion Injury via MerTK
H. Zhang¹, M. Ni², J. Zhang¹, R. Busuttil¹, J. Kupiec-Weglinski¹, W. Li³, X. Wang², Y. E. Zhai¹
¹Dumont-UCLA Transplant Center, Los Angeles, CA, ²The First Affiliated Hospital of Nanjing Medical University, Nanjing, China, ³China-Japan Union Hospital of Jilin University, JiLing, China
*Purpose: We have shown previously that glycogen synthase kinase β (Gsk3β) regulates liver inflammatory activation against ischemia/reperfusion injury (IRI). The question of whether it also…
2022 American Transplant Congress
A Multicenter Randomized Controlled Trial To Compare The Efficacy Of Ex-vivo Machine Perfusion With Static Cold Storage In Human Liver Transplantation: The University Of Maryland Experience
J. Avruch¹, N. Goussous², S. Malik¹, M. Pinedo¹, R. Meier¹, C. Bhati¹, D. Maluf¹, R. Barth³, J. Alvarez-Casas¹
¹Transplant Surgery, University of Maryland School of Medicine, Baltimore, MD, ²Transplant Surgery, University of California Davis Health, Davis, CA, ³University of Chicago, Chicago, IL
*Purpose: There is accumulating clinical evidence of the benefit of normothermic ex-vivo machine perfusion (NMP) compared with traditional static cold storage of liver allografts prior…
2022 American Transplant Congress
Mortality and Cardiovascular Outcomes in Adult Non-Liver Solid Organ Transplant Patients with Non-Alcoholic Steatohepatitis
N. Dutta¹, N. Marka², J. Lake¹, N. Lim¹
¹Medicine, University of Minnesota, Minneapolis, MN, ²Clinical and Translational Sciences Institute, University of Minnesota, Minneapolis, MN
*Purpose: Despite the increasing incidence of non-alcoholic steatohepatitis (NASH) worldwide, its impact on mortality or major adverse cardiovascular events (MACE) in non-liver solid organ transplant…
2022 American Transplant Congress
Sodium-Glucose Cotransporter 2 Inhibitors to Treat Diabetes Mellitus After Kidney Transplant
H. M. Brokmeier¹, S. B. Leung¹, A. Kukla², K. C. Mara³, P. Shah⁴, Y. Kudva⁴, G. K. Mour⁵, H. M. Wadei⁶, J. M. Hill⁷, M. D. Stegall⁸, A. Lemke¹
¹Pharmacy, Mayo Clinic, Rochester, MN, ²Division of Nephrology and Hypertension, Mayo Clinic, Rochester, MN, ³Health Sciences Research, Mayo Clinic, Rochester, MN, ⁴Endocrinology, Diabetes, Metabolism, and Nutrition, Mayo Clinic, Rochester, MN, ⁵Nephrology Transplant, Mayo Clinic, Phoenix, AZ, ⁶Nephrology, Mayo Clinic, Jacksonville, FL, ⁷Transplant, Mayo Clinic, Rochester, MN, ⁸Division of Transplant Surgery, Mayo Clinic, Rochester, MN
*Purpose: This study describes experience prescribing sodium-glucose cotransport 2 inhibitors (SGLT2i) after kidney transplant to evaluate safety and effectiveness.*Methods: This is a retrospective, institutional review…
2022 American Transplant Congress
Costs Associated with Induction Therapy for Pediatric Kidney Transplantation
N. M. Rodig¹, H. Pizzo², D. Levy Erez³, T. Richardson⁴, M. Somers¹
¹Boston Children's Hospital, Boston, MA, ²Cedars-Sinai Medical Center, Los Angeles, CA, ³Children’s Hospital of Philadelphia, Philadelphia, PA, ⁴Children's Hospital Association, Lenexa, KS
*Purpose: Choice of induction agent for pediatric kidney transplantation (KTx) is often based upon patient characteristics and center practice; costs associated with this choice have…
2022 American Transplant Congress
Predictive Value of Abnormal Hemodynamic Response to Dobutamine Stress Echocardiography in Liver Transplant Recipients
M. Groose, A. Peotter, L. Hammel
University of Wisconsin Hospitals and Clinics, Madison, WI
*Purpose: Dobutamine stress echocardiography (DSE) is an effective tool for perioperative cardiac risk stratification in patients without end-stage liver disease (ESLD). However, DSE is frequently…
2022 American Transplant Congress
Association Between Allograft Gene Expression and Acute Cellular Rejection Grade in Heart Transplant Recipients
A. Kao¹, K. Haffey², K. T. Gondi³, J. Linard², C. Knutson², K. Morgan², L. Teterina², S. Williams², K. Oreschak⁴, H. Zhang⁴
¹St. Luke's Health System Kansas City Mid America Heart Institute, Kansas City, MO, ²St. Luke's, Kansas City, MO, ³University of Michigan, Ann Arbor, MI, ⁴CareDx, South San Francisco, CA
*Purpose: Endomyocardial biopsy (EMB) remains the gold standard in acute rejection (AR) surveillance in heart transplantation (HT) despite interpretation subjectivity and low concordance rates between…
2022 American Transplant Congress
Reducing Financial Burden for Living Donors: A Single Center Experience of Increased National Living Donor Assistance Center (NLDAC) Support
T. Klair, K. Throgmorton, D. Oviedo, E. Cepeda
Transplant Center, University of Texas Health San Antonio, San Antonio, TX
*Purpose: National Living Donor Assistance Center (NLDAC) offers assistance to overcome some of the financial barriers associated with Living Donation. From 2015 to 2020, an…
2022 American Transplant Congress
Cold Ischemic Time and Kidney Graft Failure; Mediation Through Delayed Graft Function
J. Miller¹, W. Irish², D. Sawinski³, A. Massie⁴, J. Snyder¹
¹Scientific Registry of Transplant Recipients, Minneapolis, MN, ²Department of Surgery, East Carolina University, Greenville, NC, ³Division of Nephrology and Hypertension, Weill Cornell Medical College, New York, NY, ⁴Division of Surgery, Johns Hopkins School of Medicine, Baltimore, MD
*Purpose: Delayed graft function (DGF) has been associated with decreased graft survival and prolonged cold ischemia time (CIT) has been proposed as a modifiable DGF…
2022 American Transplant Congress
EBV+ PTLD Tumor MicroRNAs Detected in Circulating Extracellular Vesicles Are Decreased in Pediatric Transplant Recipients with EBV+ PTLD
A. Sen¹, J. Enriquez¹, M. Rao¹, M. Glass¹, Y. Balachandran¹, S. Syed¹, C. Twist¹, K. Weinberg¹, S. D. Boyd¹, D. Bernstein¹, A. Trickey¹, D. Gratzinger¹, B. Tan¹, M. G. Lapasaran¹, M. A. Robien², M. Brown³, B. Armstrong⁴, M. Sever⁴, D. Desai⁵, G. Mazariegos⁶, C. Chin⁷, T. Fishbein⁸, R. S. Venick⁹, A. Tekin¹⁰, H. Zimmermann¹¹, R. U. Trappe¹², C. O. Esquivel¹, O. M. Martinez¹, S. M. Krams¹
¹Stanford U, Palo Alto, CA, ²NIH, Bethesda, MD, ³NIAID, Bethesda, MD, ⁴Rho, Durham, NC, ⁵UT Southwestern, Dallas, TX, ⁶Pittsburgh U, Pittsburgh, PA, ⁷CCHMC, Cincinnati, OH, ⁸Georgetown U, Washington, DC, ⁹UCLA, LA, CA, ¹⁰Miami U, Miami, FL, ¹¹DIAKO Ev. Diakonie-Krankenhaus, Bremen, Germany, ¹²Charité - Universitätsmedizin, Berlin, Germany
*Purpose: Post-transplant lymphoproliferative disorder (PTLD) is a serious complication of solid organ transplantation. Predisposing factors for PTLD include primary Epstein-Barr virus (EBV) infection in children,…