ATC Abstracts

American Transplant Congress abstracts

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  • 2018 American Transplant Congress

    The Prognostic Implications of Renal Function Recovery and Delayed Graft Function in Kidney Transplantation

    S. Sandal, M. Cantarovich, A. Ramankumar, N. Saberi, C. Saw, D. Baran, P. Chaudhury, S. Paraskevas, J. Tchervenkov.

    MUHC, Montreal, Canada.

    Introduction: Lack of renal function recovery (RFR), 90 days after acute kidney injury (AKI) is a contributor to inferior renal outcomes and mortality. Ischemia and…
  • 2018 American Transplant Congress

    Molecular Injury and Repair Assessment in Ex Vivo Perfused Swine Heart Transplants

    N. Herbers, S. Hatami, P. Dromparis, J. Nagendran, M. Mengel, D. Freed, B. Adam.

    University of Alberta, Edmonton, Canada.

    Background: Cardiac transplantation is a life-saving intervention for advanced heart failure but it is unfortunately limited by a critical shortage of suitable donor organs and…
  • 2018 American Transplant Congress

    Survival in Deceased Donor Kidney Transplant by Kidney Donor Profile Index versus Intensive Home Hemodialysis

    A. Nishio-Lucar,1 G. Lyons,2 S. Bose,3 J. Ma,2 K. Awuah,3 R. Lockridge.3

    1Internal Medicine, University of Virginia, Charlottesville, VA; 2Public Health Science, University of Virginia, Charlottesville, VA; 3Lynchburg Nephrology Physicians, Lynchburg, VA.

    In an era of donor scarcity, high Kidney Donor Profile Index (KDPI) >85% organs can serve as a pathway to timely transplant. We previously reported…
  • 2018 American Transplant Congress

    A Phase I/II, Double-Blind, Placebo-Controlled Study Assessing Safety and Efficacy of C1 Esterase Inhibitor for Prevention of Delayed Graft Function in Deceased Donor Kidney Transplant Recipients

    S. Jordan,1 J. Choi,1 O. Aubert,2 M. Haas,3 A. Loupy,2 E. Huang,1 A. Peng,1 I. Kim,1 S. Sethi,1 S. Louie,1 D. Puliyanda,1 A. Vo.1

    1Comprehensive Transplant Center, Cedars-Sinai Medical Center, Los Angeles, CA; 2Paris Translational Research Center for Organ Transplantation, Necker Hospital, Paris, France; 3Pathology, Cedars-Sinai Medical Center, Los Angeles, CA.

    Background: Delayed graft function (DGF)in kidney allograft recipients is traditionally defined as need for dialysis during the first week after transplantation. DGF is related to…
  • 2018 American Transplant Congress

    Does Pre-Operative Angiographic Kidney Embolization Decrease Complications in Allograft Nephrectomy?

    D. Harriman, V. Mujumdar, A. Farney, J. Rogers, G. Orlando, A. Reeves-Daniel, R. Stratta.

    Surgery, Medicine, Wake Forest Baptist Health, Winston-Salem, NC.

    Introduction: Morbidity associated with allograft nephrectomy (AN) for treatment of failed or diseased kidney transplants is well documented. Pre-operative angiographic kidney embolization (PAKE), which induces…
  • 2018 American Transplant Congress

    Urine Podocin mRNA to Nephrin mRNA Ratio as a Marker of "Podocyte Stress" among Kidney Allografts Losing Function

    A. Naik,1 J. Aqeel,1 D. Cibrik,2 M. Samaniego,1 S. Wang,1 M. Chowdhury,1 F. Afshinnia,1 R. Wiggins.1

    1Univ of Michigan, Ann Arbor; 2Univ of Kansas, Kansas City.

    Increasing data supports the hypothesis that long term allograft loss-of-function is associated with progressive glomerulosclerosis (GS). In models of progressive GS the ratio of two…
  • 2018 American Transplant Congress

    Comparison of Outcomes in African-American and White Primary Kidney Transplant Recipients: A Matched-Pair Analysis

    F. Tedla, A. Brar, D. John, N. Sumrani, R. Gruessner, A. Gruessner, M. Salifu.

    SUNY Downstate Medical Center, Brooklyn, NY.

    Background: Racial differences in clinical and sociodemographic characteristics have been well recognized. This study aims to assess outcomes in African-American (AA) and white primary deceased…
  • 2018 American Transplant Congress

    Donor Specific Antibodies Increase the Risk of Preeclampsia in Pregnant Kidney Transplant Recipients

    M. Lubetzky, T. Muthukumar, J. Lee, J. Lee, C. Hartono, L. Mahla, D. Serur, D. Dadhania.

    Weill Cornell-New York Presbyterian, NY, NY.

    Kidney transplant recipients are at an increased risk for pregnancy-associated complications including preeclampsia (PEC). Endothelial injury in the placenta is a hallmark of PEC. The…
  • 2018 American Transplant Congress

    High Calcineurin Inhibitor Intra Patient Variability is Associated with Early Renal Allograft Inflammation, Chronicity and Loss

    A. Sharma,1 A. Cherukuri,2 R. Mehta,1 P. Sood,1 S. Hariharan.1

    1Thomas E. Starzl Transplantation Institute, University of Pittsburgh Medical Center, Pittsburgh, PA; 2Thomas E. Starzl Transplantation Institute, University of Pittsburgh, Pittsburgh, PA.

    High CNI IPV has been associated with poor kidney allograft outcomes, albeit in small limited studies. We evaluated effect of CNI IPV (the degree of…
  • 2018 American Transplant Congress

    Allogeneic Mesenchymal Stem Cells as Induction Therapy Are Safe and Feasible in Renal Allografts: Pilot Results of a Multicenter Randomized Controlled Trial

    Q. Sun,1 F. Han,1 M. Zhao,2 R. Cao,3 D. Zhao,1 Z. Huang,1 L. Hong,1 Y. Peng,1 Q. Sun.1

    1Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, China; 2Zhujiang Hospital, Southern Medical University, Guangzhou, China; 3Second Affiliated Hospital, Guangzhou Traditional Chinese Medicine University, Guangzhou, China.

    Background: Delayed graft function (DGF) and acute rejection lead to adverse effects on graft outcomes. Optimal induction intervention should include both renal structure injury repair…
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