ATC Abstracts

American Transplant Congress abstracts

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  • 2022 American Transplant Congress

    Optimizing Multimodal Pain Control Post Laparoscopic Living Donor Nephrectomy

    J. Francois Whitt1, A. Centeno1, T. Harrison1, P. Cabrera1, S. Zahid1, L. Chen2

    1Jackson Memorial Hospital, Miami, FL, 2University of Miami/Jackson Memorial Hospital, Miami, FL

    *Purpose: The purpose of this study is to examine the use of a multimodal pain regimen in our diverse population to better characterize short and…
  • 2022 American Transplant Congress

    Clusterin Protects Kidney Transplants from Ischemia-Reperfusion Injury by Modulating Neutrophil Infiltration

    Y. Shim1, R. Fan2, N. Dvorina2, K. McCrae1, B. William2

    1Cardiovascular and Metabolic Sciences, Cleveland Clinic Lerner Research Institute, Cleveland, OH, 2Inflammation and Immunity, Cleveland Clinic Lerner Research Institute, Cleveland, OH

    *Purpose: Ischemia-reperfusion injury (IRI) is inevitable during organ transplantation. Clusterin (CLU) has shown to be protective in IRI. Supplementation of storage solution with recombinant CLU…
  • 2022 American Transplant Congress

    Normal Saline vs Electrolyte-a Use Peri- and Post-Operatively in Adult Kidney Transplant Recipients

    K. R. Szempruch, A. D. Martschenko, H. Arora, R. Isaak, R. Prasad, P. Serrano

    UNC Medical Center, Chapel Hill, NC

    *Purpose: 0.9% normal saline (NS) has been used as the standard fluid replacement in kidney transplant recipients (KTRs) to prevent dehydration and to improve renal…
  • 2022 American Transplant Congress

    An Acceptable Challenge for Specialized Transplant Centres: Small Kidney Donors for Small Recipients

    R. Büscher, M. Cetiner, P. F. Hoyer, A. K. Büscher

    Department of Pediatrics II, University Hospital Essen, Essen, Germany

    *Purpose: Kidneys from small donors (SDK, donor weight
  • 2022 American Transplant Congress

    SARS-CoV-2 Infection is Associated with Greater Neutralizing Antibody Response Compared to Three Doses of Mrna-1273 Vaccine in Solid Organ Transplant Recipients

    V. H. Ferreira, V. Hall, T. M. Marinelli, M. Ierullo, V. Kulasingam, A. Humar, D. Kumar

    University Health Network, Toronto, ON, Canada

    *Purpose: Prior studies suggest that two doses of mRNA vaccine in SOTR may result in lower antibody and T-cell responses relative to levels seen following…
  • 2022 American Transplant Congress

    De Novo Focal Segmental Glomerulosclerosis in the Kidney Allograft: Association with Alloimmunity Leading to Poor Outcome

    J. Leon1, J. Duong Van Huyen2, A. Abderrahmane1, D. Anglicheau1, C. Legendre1, M. Rabant2

    1KIDNEY TRANSPLANTATION, Necker Hospital, Paris, France, 2KIDNEY PATHOLOGY, Necker Hospital, Paris, France

    *Purpose: Focal Segmental Glomerulosclerosis (FSGS) can be found de novo (Dn) or as a recurrence in kidney allograft. While FSGS recurrence has been extensively described…
  • 2022 American Transplant Congress

    Unravelling the Stage-Shift of Acute Rejection by Urine QSant

    W. Yazar1, N. Titzler1, R. Sarwal1, M. Sarwal2, S. Ghosh1

    1Nephrosant, Brisbane, CA, 2NephroSant, Brisbane, CA

    *Purpose: Suboptimal performance in current methods for allograft monitoring underscores the unmet need for enhanced immunosurveillance accuracy, to uncover the alloimmunity flux. QSant[Yang et al,…
  • 2022 American Transplant Congress

    Pd-1 Licenses Activated Treg for Lymphatic Migration

    W. Piao1, L. Li1, V. Saxena1, K. Hippen2, M. Shirkey1, B. Blazar2, I. Lape3, y. zhang3, J. Bromberg1

    1Surgery, University of Maryland, Baltimore, MD, 2University of Minnesota, Minneapolis, MN, 3Harvard Medical School, Boston, MA

    *Purpose: In addition to serving as fluid conduits, lymphatic vessels are critical portals for immune cell migration. Lymphatic endothelial cells (LECs) constitutively express high levels…
  • 2022 American Transplant Congress

    MTOR Inhibition Acts Directly on Endothelial Cells to Induce Contact-Independent Immune-Modulation of Allo-Specific T Cell Activation

    H. Xu, L. Wang, V. A. Bendersky, Q. Gao, Q. Li, A. D. Kirk, H. Xu

    Duke University School of Medicine, Durham, NC

    *Purpose: Endothelial cells (ECs) form a barrier between vascularized organ allografts and host immunity and are known to provoke alloimmune responses. The mTOR inhibitor rapamycin…
  • 2022 American Transplant Congress

    Impact of Immunosuppression on T-cell Responses After mRNA-Based Sars-CoV-2 Vaccination

    E. Wong1, N. L. Bert2, H. K. Sran1, A. Lim1, M. D'Costa1, K. Akalya2, S. Hang2, A. Bertoletti2, A. Vathsala1

    1National University Centre for Organ Transplantation, National University Hospital, Singapore, Singapore, 2Programme in Emerging Infectious Diseases, Duke-National University of Singapore Medical School, Singapore, Singapore

    *Purpose: Administration of mRNA-based SARS-CoV-2 vaccines confers protection from SARS-CoV-2 infection and reduces its severity in the general population. It has been suggested that mounting…
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